About LA-3 by Live Cell Research

LA-3 by Live Cell Research is a nutritional supplement that promises to boost your AMPK levels, resulting in increased energy, clearer thinking, decreased abdominal fat, and a “stronger, healthier body.” For these reasons, Live Cell Research calls LA-3 a “longevity activator.”

How? According to the company, LA-3 contains three different ingredients that have never been combined before, which can provide maximum benefits after just a few months of continuous use:

  • Days 1-7: You may begin experiencing increased energy and reduced appetite and cravings.
  • Days 7-30: Because you’re eating less, you might notice your abdominal fat melting away, further increasing your energy.
  • 1 Month+: After this time, we’re told your AMPK levels should be elevated sufficiently so that your thoughts become clearer and your mind less forgetful. You might also notice that your body is becoming stronger and healthier, along with a continued change in your shape.

To achieve these benefits, Live Cell Research states you'll just need to take two capsules of LA-3 with water per day, with or without food. They also promise that LA-3 can work for anyone, is safe to use with no known side effects, and is third-party tested for safety, purity, and potency.

If you didn’t know better, Live Cell Research’s LA-3 supplement might sound like some fountain of youth and an incredible weight loss program rolled into one.

But what does science have to say about many of the company's claims? Will this supplement work? Is it worth the money? Keep reading to find out what we uncovered during our research.

What is AMPK? How Does It Work?

5' AMP-activated protein kinase (or AMPK for short) is “an enzyme that plays a role in cellular energy homeostasis,” and is concentrated in a number of areas throughout the human body, including the brain, liver, and skeletal muscle. AMPK itself is made up of three proteins: STE-related adaptor (STRAD), mouse protein 25 (MO25), and LKB1.

Live Cell Research calls AMPK a “master switch” because this enzyme regulates several key systems within the body, such as increasing cellular energy, stimulating the oxidation of fatty acids and glucose transport, and more.

While the exact details are far outside the scope of this review (and they might make you go cross-eyed), the thing about AMPK is that some fairly specific conditions need to be present for the enzyme to be activated—the primary method of which is muscle contraction (i.e. working out).

Once AMPK is activated, there is some clinical evidence showing it may increase blood supply to muscles, help transport glucose (simple sugars), boost fatty acid metabolism (thereby creating more energy for the cell), and more.

What if you don't want to hit the gym to boost your AMPK levels? Can you accomplish the same thing by popping a couple of LA-3 pills?

Will LA-3’s Ingredients Boost Your AMPK Levels?

According to their supplement label, LA-3 contains the following ingredients:

Of these, WebMD indicates that 30mg daily of gynostemma may be effective for reducing cholesterol. So, at 450mg per dose, LA-3 delivers significantly more than this, although there doesn’t seem to be any clinical evidence indicating that increased gynostemma consumption results in more obvious benefits.

Is ActivAMP a Clinically Proven Ingredient?

Important note: The gynostemma pentaphyllum found in LA-3 is part of a proprietary ingredient named ActivAMP, which is manufactured by a company named Gencor Pacific.

According to their website, in a 12-week randomized clinical trial, ActivAMP was shown to decrease body fat mass and body fat percentage, reduce body weight and BMI, and shrink the total abdominal area.

To see the results for ourselves, we reached out to Gencor Pacific and obtained some of their clinical evidence for ActivAMP, which consists of seven different trials. Here is just a handful:

  • A 2013, 23-week randomized, double-blind, placebo-controlled clinical trial that concluded ActivAMP might be useful for treating obese individuals.
  • A 2012, 8-week study that showed mice “decreased body weight gain, liver weight, and blood cholesterol levels with AMPK activation in the soleus muscle.”
  • A 2011 study showing the ingredient may be effective for improving glucose and lipid metabolism.
  • A 2008 study showing that ginsenosides may have an anti-obesity effective. All results were obtained via cells in a controlled laboratory setting.

Now, we’re not medical experts (which is why we rely on authoritative sites to determine whether or not an ingredient is classified as “effective”), so we have no reason to doubt the findings in Gencor Pacific’s research.

Just keep in mind that results obtained through experiments conducted on mice and cells don’t necessarily mean you, as a human, will experience the same thing.

And even if these studies were conducted on humans, it would require dozens (or perhaps even hundreds) of reproducible, double-blind, placebo controlled, peer reviewed studies before if could be considered “proven” to work as advertised.

For more about this topic, be sure to read Think That Clinical Study Is Legit?

LA-3’s Other Ingredients

Moving on, WebMD also tells us that 1,000mg daily of quercetin (commonly known as jiaogulan) might help alleviate prostate pain and inflammation. But at just 100mg per dose, there doesn’t appear to be enough in LA-3 to provide these benefits.

Finally, WebMD indicates that berberine might also be effective at reducing cholesterol, as well as blood sugar levels in diabetes patients.

Bringing It All Together Regarding LA-3’s Ingredients: What Can You Realistically Expect?

As we can see, there are clearly some clinically validated benefits for the ingredients found in LA-3.

However, according to authoritative websites like WebMD, there doesn’t appear to be enough clinical evidence showing that these ingredients—whether on their own or in combination—can elevate AMPK levels.

Granted, there is some promising research related to AMPK, although most clinical studies have been conducted on mice (including one of the studies for ActivAMP).

So, based on what we learned after reaching out to Live Cell Research, there seems to be little clinical proof that these same protocols will work in humans.

Are There Any Potential Side Effects From LA-3?

Despite the limited evidence showing that these ingredients can boost AMPK levels, the good news is that they’re generally considered safe.

However, WebMD notes that gynostemma pentaphyllum “can cause some side effects such as severe nausea and increased bowel movements.” Also, it’s unknown if taking quercetin for more than 12 weeks is considered safe.

How much will you pay for LA-3’s three-ingredient formulation?

How Much Does LA-3 Longevity Activator Cost?

Live Cell Research’s LA-3 supplement is available in the following quantities:

  • 1 Bottle: $46.99
  • 3 Bottles: $117
  • 6 Bottles: $216

Like all Live Cell Research products, LA-3 comes with a 90-day refund policy, less S&H charges. To request one, you'll need to contact customer service at (844) 650-5933 or support@LiveCellResearch.com.

Based on these prices, are LA-3’s customers generally satisfied with what they get for their money?

What Can We Learn From LA-3 Customer Reviews?

Since conducting our original research, 19 LA-3 customers have written about their experience on HighYa, giving the supplement an average rating of 3.8 stars.

Here, most compliments seem to reference effective results, including reduced belly fat, increased energy, improved weight loss, and decreased appetite and cravings.

On the other hand, as is the case with many other nutritional supplements, the most common customer complaint about LA-3 seems related to ineffective (or non-existent) results. In fact, even among those who experienced positive results, several noted that it took several weeks to achieve any effects and that they were fairly mild.

Granted, all of this relates to LA-3 as a product. What about the company who manufactures it?

Who is Live Cell Research? Are They Reputable?

Live Cell Research is based out of Southern California, where they manufacture a line of popular supplements, including Niagen, Cerastim, Midogen, Vital Stem, and more.

Overall, the company’s supplements seem to come with mostly positive online customer reviews, with common compliments citing effective results. On the flip side, common complaints reference failure to work/achieve results and difficult customer service experiences.

Unfortunately, the company wasn’t listed with the Better Business Bureau at the time of our research. Let’s bring it all together, shall we?

Is LA-3 the Right Nutritional Supplement for You?

On the one hand, with many of the Live Cell Research products we’ve written about in the past, authoritative websites like WebMD note that the clinical evidence supporting many of the company’s claims is lacking.

On the other hand, many customers claim to have experienced positive results with the company’s supplements—LA-3 included—clinical evidence notwithstanding.

Does this mean you should hand over your hard-earned money for Live Cell Research’s LA-3 supplement? Like any other nutritional supplement, what works fantastically for you might be a total flop for someone else, and vice versa.

The seemingly good news is that Live Cell Research offers a 90-day refund window on all of their products, which you can take advantage of if you’re not fully satisfied. Just keep in mind that you'll be out a few dollars for return shipping and handling.

Finally, if you type the phrase “AMPK supplement” or “AMPK activator” into your favorite search engine, you’ll be met with dozens of supplements making many of the same claims as LA-3, including Life Extension.

Sure, they might not be formulated exactly like LA-3, but their claims (and general lack of clinical support) are much the same.

Were you pleased with LA-3’s performance? Or, do you feel it was a waste of money? Whatever your experience, we want to hear about it—be sure to leave a review below!

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272 Customer Reviews for LA-3 by Live Cell Research

Average Customer Rating: 4.1
Rating Snapshot:
5 star: 134 4 star: 86 3 star: 21 2 star: 9 1 star:  22
Bottom Line: 86% would recommend it to a friend
Showing 1-11 of 272
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  • 0 out 1 people found this review helpful

    LA-3 is worthless

    • North Dakota,
    • Jun 20, 2017
    • Verified Reviewer

    I purchased four bottles of LA-3 after watching the promo video hoping that it would work. After receiving the product, I started using it daily following the dosage listed on the product. Nothing happened. While taking LA-3, I followed a low carb diet and got adequate exercise. After two weeks, nothing changed, and with no decrease in belly fat (as determined by measurement). After the first bottle, no change.

    Hoping that my body needed more time to adjust to LA-3, I continued to take LA-3 as directed. Now, after four bottles (all I ordered) nothing happened. It appears that I fell for another weight scheme. I should know better. Don't waste your money on this junk.

    Bottom Line: No, I would not recommend this to a friend

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  • 2 out 2 people found this review helpful

    Unexpected bad side effect

    I was very excited to start this product. One week in, I became extremely depressed, crying all the time, couldn't get myself in motion. Not me at all. I accidentally forgot to take them for two days and felt better. I didn't make the connection but felt my old self again. I started taking them again for another week and got the same depression, so then I decided it might be this product. I stopped and felt better. I did this one more time to just be sure, and sure enough.

    This is likely unusual but worth noting in the event that anyone experiences similar effects. I am disappointed it didn't work for me.

    Bottom Line: No, I would not recommend this to a friend

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  • 5 out 6 people found this review helpful

    LA-3

    • Waikato, New Zealand,
    • Jun 16, 2017
    • Verified Reviewer

    I have been taking LA-3 for six weeks now with absolutely no sign of any weight or waist loss, nor any noticeable improvement in energy levels. I will finish the second bottle, and it looks like claiming a refund will be my next move unless a miracle happens in the next two weeks.

    Bottom Line: No, I would not recommend this to a friend

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  • 4 out 5 people found this review helpful

    Feeling 15 years younger

    • Omaha, NE,
    • Jun 10, 2017
    • Verified Reviewer

    I went on and on about my positive experiences with this product. Apparently, I exceeded the number of characters allowed, because all my comments are eliminated!

    To sum up: I feel 15 years younger, both mentally and physically! I want more of this product. I've been using it for six months.

    Bottom Line: Yes, I would recommend this to a friend

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  • 2 out 4 people found this review helpful

    Side affects

    • Jun 9, 2017
    • Verified Reviewer

    Hello, my name is Nelly, and I started taking the LA-3 on Monday, June 5th, 2017, and since Tuesday I have been feeling dizzyness, vertigo, and nausea. I am not sure if this is the pills, but I was fine before taking them. I am off to see my doctor about this. Also, my eyes feel kind of heavy and I have redness to them. Please advice. Thank you.

    Bottom Line: No, I would not recommend this to a friend

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    • Jun 9, 2017

      Live Cell Research Rep, Customer Relations Manager

      Hello Nelly, thank you for leaving us a review of your experience with one of our best selling products, LA-3. We always recommend speaking to your primary physician, when taking any new supplements to ensure that they will not have any adverse effects on or interfere with anything else you may already be taking. Please be assured that we always stand by our 90-day money back guarantee on all of our products. If you wish to return the LA-3 for a full refund, please email me personally at aurora@livecellresearch.com. Thank you Nelly.

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  • 4 out 5 people found this review helpful

    Best product

    I saw an increase of energy in the second day, started losing body fat after the first week, had no more foggy memory, and I sleep better. I am in the fourth week of taking them, and I love it. I would recommend it to anyone.

    Bottom Line: Yes, I would recommend this to a friend

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  • 16 out 18 people found this review helpful

    LA-3 actually works

    • Sarasota, FL,
    • Jun 2, 2017
    • Verified Reviewer

    I have tried every diet pill and gimmick out there spending a lot of money, and nothing ever worked! I have hit menopause and struggled with the weight gain. I worked out and wasted a lot of money on pills and diets that never worked. I cannot believe how GREAT this product is. I have dropped 4 lbs in two weeks. I can see the difference, and I would recommend this product to anyone. I would stand behind this product. Good luck. If you don't try this product, you will lose!

    Thank you LA-3. Love this!

    Bottom Line: Yes, I would recommend this to a friend

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  • 11 out 11 people found this review helpful

    More energy

    LA-3 has helped me up my energy level. It has helped with being able to sleep better and wake up refreshed most every day. I have fibromyalgia and the constant fatigue made it very hard some days to be able function at my full potential.

    With fibro you have anxiety and LA-3 has helped bring that down with keeping my energy level up. I feel like I have lost some weight.

    I know it will take some time to see better results losing the weight that I would like to loose. I am curious to see what difference I see and feel at the end of two months.

    Bottom Line: Yes, I would recommend this to a friend

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  • 11 out 13 people found this review helpful

    Not happy about this at all

    • New Jersey,
    • May 27, 2017
    • Verified Reviewer

    I've been using LA-3 for three weeks now, and I've gained weight! I don't know if its just water weight, but I am NOT happy about this at all. Is this happening to others? I work out, eat fairly well, so I would not expect to put on seven pounds in such a short period of time. What the heck is going on?

    Bottom Line: No, I would not recommend this to a friend

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    Comments (3)
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    • May 30, 2017

      Live Cell Research Rep, Customer Relations Manager

      Hello Gerry, Aurora here with Live Cell Research. I am sorry to hear that you did not receive the results you had expected from using LA-3. While a majority of our customers see results within the first month of using our product, we understand that everyone is different. This is why we always offer our 90-day money back guarantee. I would like to hear more about your time with LA-3 so that I can help you experience all of its great benefits. Please email me directly at aurora@livecellresearch.com so I can help, thanks Gerry!

    • Jun 10, 2017

      Janis Larson

      I didn't lose weight and now I'm on my second bottle. It still does not work. I had a stroke, so I hope to reduce my blood pressure I took blood work at the lab, and now it's 30 percent higher. That's my problem with LA-3, I think I should mail you the pills back so I can get refunded. I have six bottles. They are not working.

    • Jun 15, 2017

      Live Cell Research Rep, Customer Relations Manager

      Hello Janis, thank you for providing us with your feedback. Please keep in mind that it is very important to consult your physician prior to starting any new supplement, especially if prior medical conditions occur. LA-3 is not intended for people with high blood pressure or history of strokes. Please discontinue use immediately. I would be more than happy to issue you a full refund. Email me at Aurora@livecellresearch.com, and I would be more than happy to take care of this for you right away. Thank you!

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  • 16 out 20 people found this review helpful

    Horrible stuff, does not work

    • Peyton, CO,
    • May 20, 2017
    • Verified Reviewer

    I have been taking this for about four months, and the only thing I have experienced is a horrible case of exhaustion. We have figured out this is the ONLY thing that has changed, so it has to be this. It is a great medication for a sleep. I tried to get a hold of them for a refund, and you got it, no one would help me out, and now it is too late. Don’t waste your money.

    Bottom Line: No, I would not recommend this to a friend

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    • May 30, 2017

      Live Cell Research Rep, Customer Relations Manager

      Hello Lori, thank you for taking the time to leave a valuable review on your experience with LA-3. I am sorry to hear that you did not enjoy the product. I would be more than happy to assist you with your refund. Please email me personally at aurora@livecellresearch.com, so that I can look into this and issue you a refund for all of your purchased items. Thank you again Lori, I look forward to hearing from you.

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  • 18 out 22 people found this review helpful

    Great unexpected result

    • Clarkston, WA,
    • May 16, 2017
    • Verified Reviewer

    The third week into the first month, I noticed that my skin felt firmer and my neck looked better. I did not get the afternoon sweet craving and felt overall lighter in my midsection. My fingernails are so much stronger as well. I ordered my second month and anticipate even more great happenings within my body.

    Bottom Line: Yes, I would recommend this to a friend

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    • Jun 10, 2017

      Andrea

      Cheryl how do you feel now?

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