About LA-3 by Live Cell Research

LA-3 by Live Cell Research is a nutritional supplement that promises to boost your AMPK levels, resulting in increased energy, clearer thinking, decreased abdominal fat, and a “stronger, healthier body.” For these reasons, Live Cell Research calls LA-3 a “longevity activator.”

How? According to the company, LA-3 contains three different ingredients that have never been combined before, which can provide maximum benefits after just a few months of continuous use:

  • Days 1-7: You may begin experiencing increased energy and reduced appetite and cravings.
  • Days 7-30: Because you’re eating less, you might notice your abdominal fat melting away, further increasing your energy.
  • 1 Month+: After this time, we’re told your AMPK levels should be elevated sufficiently so that your thoughts become clearer and your mind less forgetful. You might also notice that your body is becoming stronger and healthier, along with a continued change in your shape.

To achieve these benefits, Live Cell Research states you'll just need to take two capsules of LA-3 with water per day, with or without food. They also promise that LA-3 can work for anyone, is safe to use with no known side effects, and is third-party tested for safety, purity, and potency.

If you didn’t know better, Live Cell Research’s LA-3 supplement might sound like some fountain of youth and an incredible weight loss program rolled into one.

But what does science have to say about many of the company's claims? Will this supplement work? Is it worth the money? Keep reading to find out what we uncovered during our research.

What is AMPK? How Does It Work?

5' AMP-activated protein kinase (or AMPK for short) is “an enzyme that plays a role in cellular energy homeostasis,” and is concentrated in a number of areas throughout the human body, including the brain, liver, and skeletal muscle. AMPK itself is made up of three proteins: STE-related adaptor (STRAD), mouse protein 25 (MO25), and LKB1.

Live Cell Research calls AMPK a “master switch” because this enzyme regulates several key systems within the body, such as increasing cellular energy, stimulating the oxidation of fatty acids and glucose transport, and more.

While the exact details are far outside the scope of this review (and they might make you go cross-eyed), the thing about AMPK is that some fairly specific conditions need to be present for the enzyme to be activated—the primary method of which is muscle contraction (i.e. working out).

Once AMPK is activated, there is some clinical evidence showing it may increase blood supply to muscles, help transport glucose (simple sugars), boost fatty acid metabolism (thereby creating more energy for the cell), and more.

What if you don't want to hit the gym to boost your AMPK levels? Can you accomplish the same thing by popping a couple of LA-3 pills?

Will LA-3’s Ingredients Boost Your AMPK Levels?

According to their supplement label, LA-3 contains the following ingredients:

Of these, WebMD indicates that 30mg daily of gynostemma may be effective for reducing cholesterol. So, at 450mg per dose, LA-3 delivers significantly more than this, although there doesn’t seem to be any clinical evidence indicating that increased gynostemma consumption results in more obvious benefits.

Is ActivAMP a Clinically Proven Ingredient?

Important note: The gynostemma pentaphyllum found in LA-3 is part of a proprietary ingredient named ActivAMP, which is manufactured by a company named Gencor Pacific.

According to their website, in a 12-week randomized clinical trial, ActivAMP was shown to decrease body fat mass and body fat percentage, reduce body weight and BMI, and shrink the total abdominal area.

To see the results for ourselves, we reached out to Gencor Pacific and obtained some of their clinical evidence for ActivAMP, which consists of seven different trials. Here is just a handful:

  • A 2013, 23-week randomized, double-blind, placebo-controlled clinical trial that concluded ActivAMP might be useful for treating obese individuals.
  • A 2012, 8-week study that showed mice “decreased body weight gain, liver weight, and blood cholesterol levels with AMPK activation in the soleus muscle.”
  • A 2011 study showing the ingredient may be effective for improving glucose and lipid metabolism.
  • A 2008 study showing that ginsenosides may have an anti-obesity effective. All results were obtained via cells in a controlled laboratory setting.

Now, we’re not medical experts (which is why we rely on authoritative sites to determine whether or not an ingredient is classified as “effective”), so we have no reason to doubt the findings in Gencor Pacific’s research.

Just keep in mind that results obtained through experiments conducted on mice and cells don’t necessarily mean you, as a human, will experience the same thing.

And even if these studies were conducted on humans, it would require dozens (or perhaps even hundreds) of reproducible, double-blind, placebo controlled, peer reviewed studies before if could be considered “proven” to work as advertised.

For more about this topic, be sure to read Think That Clinical Study Is Legit?

LA-3’s Other Ingredients

Moving on, WebMD also tells us that 1,000mg daily of quercetin (commonly known as jiaogulan) might help alleviate prostate pain and inflammation. But at just 100mg per dose, there doesn’t appear to be enough in LA-3 to provide these benefits.

Finally, WebMD indicates that berberine might also be effective at reducing cholesterol, as well as blood sugar levels in diabetes patients.

Bringing It All Together Regarding LA-3’s Ingredients: What Can You Realistically Expect?

As we can see, there are clearly some clinically validated benefits for the ingredients found in LA-3.

However, according to authoritative websites like WebMD, there doesn’t appear to be enough clinical evidence showing that these ingredients—whether on their own or in combination—can elevate AMPK levels.

Granted, there is some promising research related to AMPK, although most clinical studies have been conducted on mice (including one of the studies for ActivAMP).

So, based on what we learned after reaching out to Live Cell Research, there seems to be little clinical proof that these same protocols will work in humans.

Are There Any Potential Side Effects From LA-3?

Despite the limited evidence showing that these ingredients can boost AMPK levels, the good news is that they’re generally considered safe.

However, WebMD notes that gynostemma pentaphyllum “can cause some side effects such as severe nausea and increased bowel movements.” Also, it’s unknown if taking quercetin for more than 12 weeks is considered safe.

How much will you pay for LA-3’s three-ingredient formulation?

How Much Does LA-3 Longevity Activator Cost?

Live Cell Research’s LA-3 supplement is available in the following quantities:

  • 1 Bottle: $46.99
  • 3 Bottles: $117
  • 6 Bottles: $216

Like all Live Cell Research products, LA-3 comes with a 90-day refund policy, less S&H charges. To request one, you'll need to contact customer service at (844) 650-5933 or support@LiveCellResearch.com.

Based on these prices, are LA-3’s customers generally satisfied with what they get for their money?

What Can We Learn From LA-3 Customer Reviews?

Since conducting our original research, 19 LA-3 customers have written about their experience on HighYa, giving the supplement an average rating of 3.8 stars.

Here, most compliments seem to reference effective results, including reduced belly fat, increased energy, improved weight loss, and decreased appetite and cravings.

On the other hand, as is the case with many other nutritional supplements, the most common customer complaint about LA-3 seems related to ineffective (or non-existent) results. In fact, even among those who experienced positive results, several noted that it took several weeks to achieve any effects and that they were fairly mild.

Granted, all of this relates to LA-3 as a product. What about the company who manufactures it?

Who is Live Cell Research? Are They Reputable?

Live Cell Research is based out of Southern California, where they manufacture a line of popular supplements, including Niagen, Cerastim, Midogen, Vital Stem, and more.

Overall, the company’s supplements seem to come with mostly positive online customer reviews, with common compliments citing effective results. On the flip side, common complaints reference failure to work/achieve results and difficult customer service experiences.

Unfortunately, the company wasn’t listed with the Better Business Bureau at the time of our research. Let’s bring it all together, shall we?

Is LA-3 the Right Nutritional Supplement for You?

On the one hand, with many of the Live Cell Research products we’ve written about in the past, authoritative websites like WebMD note that the clinical evidence supporting many of the company’s claims is lacking.

On the other hand, many customers claim to have experienced positive results with the company’s supplements—LA-3 included—clinical evidence notwithstanding.

Does this mean you should hand over your hard-earned money for Live Cell Research’s LA-3 supplement? Like any other nutritional supplement, what works fantastically for you might be a total flop for someone else, and vice versa.

The seemingly good news is that Live Cell Research offers a 90-day refund window on all of their products, which you can take advantage of if you’re not fully satisfied. Just keep in mind that you'll be out a few dollars for return shipping and handling.

Finally, if you type the phrase “AMPK supplement” or “AMPK activator” into your favorite search engine, you’ll be met with dozens of supplements making many of the same claims as LA-3, including Life Extension.

Sure, they might not be formulated exactly like LA-3, but their claims (and general lack of clinical support) are much the same.

Were you pleased with LA-3’s performance? Or, do you feel it was a waste of money? Whatever your experience, we want to hear about it—be sure to leave a review below!

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56 Customer Reviews for LA-3 by Live Cell Research

Average Customer Rating: 4.2
Rating Snapshot:
5 stars: 23 4 stars: 26 3 stars: 3 2 stars: 1 1 stars: 3
Bottom Line: 89% would recommend it to a friend
Showing 1-11 of 56
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  • I love this product, and my husband does too!

    II love this LA-3, it was such a simple, great product to use.

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 2 people found this review helpful

    Over all improvement.

    • Homosassa, FL,
    • Jan 16, 2017

    It has been approximately 4-5 weeks since starting LA-3, and I am very happy so far with my energy level. My mental clarity is improved, and I've had a weight loss of almost 10 lbs. I have ordered a three-month supply in hopes that this progress continues. Will keep you all posted!

    Bottom Line: Yes, I would recommend this to a friend

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  • 3 out 3 people found this review helpful

    Good product

    This product has greatly curbed my appetite and has boosted my metabolism. I have lost my desire for sweets and have lost five lbs so far in the two weeks I have been using it.

    Bottom Line: Yes, I would recommend this to a friend

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  • 4 out 4 people found this review helpful

    Progress

    It's been 26 days and I have seen shrinkage of my belly. Also, a slight increase in energy. I eat the same and have not increased my activity.

    Bottom Line: Yes, I would recommend this to a friend

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  • 6 out 7 people found this review helpful

    LA-3 1st day

    I wrote a review earlier but forgot to mention that my feet always ache and not only did my sinuses open and breathing become clear, but I immediately felt the pain in both feet leave. When I woke up the next morning, my breathing was still better, and my feet do not hurt. All from just taking only two capsules my first day. This is really true, no one told me to say this, I cannot wait to take today's dose.

    Bottom Line: Yes, I would recommend this to a friend

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  • 5 out 5 people found this review helpful

    It works as advertised!

    • Lake Charles, LA,
    • Jan 14, 2017

    I have been taking two pills each morning and my stomach has gone down considerably, and I haven't finished the first bottle yet.

    Bottom Line: Yes, I would recommend this to a friend

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  • 3 out 3 people found this review helpful

    LA-3 1st day

    After I took two of the capsules my breathing became clear and I felt good. I know it was my first time but I truly did feel good.

    Bottom Line: Yes, I would recommend this to a friend

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  • 2 out 2 people found this review helpful

    I want to run around with my granddaughters

    I am 65 years old and I see the changes already. I am going to place an order for more.

    Bottom Line: Yes, I would recommend this to a friend

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  • 2 out 2 people found this review helpful

    Like this product

    So far I have been happy with this product. I have noticed a change in my appetite, and I have more energy. I have only used it for 30 days and look forward to continued use to see more effects.

    Bottom Line: Yes, I would recommend this to a friend

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  • 5 out 5 people found this review helpful

    Worked

    • Franklin Square, NY,
    • Jan 13, 2017

    I have been using it for three weeks. I have no appetite, I force myself to eat, but I used to eat nonstop.

    Bottom Line: Yes, I would recommend this to a friend

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  • 5 out 5 people found this review helpful

    I see a difference

    I have missed a couple of days but its because of my schedule, and I also have fibro and bad arthritis, which makes regular exercise a challenge. But that being said, I have noticed a slight difference in my appearance and general well-being.

    The winter cold hits me hard so I tend to sleep more, and and the holidays don't help with so many goodies readily available, but I think I have been doing well since LA-3 has definitely helped my cravings and curb my appetite. I will continue to use it and try to be patient for more changes.

    Bottom Line: Yes, I would recommend this to a friend

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Showing 1-11 of 56

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