About LA-3 by Live Cell Research

LA-3 by Live Cell Research is a nutritional supplement that promises to boost your AMPK levels, resulting in increased energy, clearer thinking, decreased abdominal fat, and a “stronger, healthier body.” For these reasons, Live Cell Research calls LA-3 a “longevity activator.”

How? According to the company, LA-3 contains three different ingredients that have never been combined before, which can provide maximum benefits after just a few months of continuous use:

  • Days 1-7: You may begin experiencing increased energy and reduced appetite and cravings.
  • Days 7-30: Because you’re eating less, you might notice your abdominal fat melting away, further increasing your energy.
  • 1 Month+: After this time, we’re told your AMPK levels should be elevated sufficiently so that your thoughts become clearer and your mind less forgetful. You might also notice that your body is becoming stronger and healthier, along with a continued change in your shape.

To achieve these benefits, Live Cell Research states you'll just need to take two capsules of LA-3 with water per day, with or without food. They also promise that LA-3 can work for anyone, is safe to use with no known side effects, and is third-party tested for safety, purity, and potency.

If you didn’t know better, Live Cell Research’s LA-3 supplement might sound like some fountain of youth and an incredible weight loss program rolled into one.

But what does science have to say about many of the company's claims? Will this supplement work? Is it worth the money? Keep reading to find out what we uncovered during our research.

What is AMPK? How Does It Work?

5' AMP-activated protein kinase (or AMPK for short) is “an enzyme that plays a role in cellular energy homeostasis,” and is concentrated in a number of areas throughout the human body, including the brain, liver, and skeletal muscle. AMPK itself is made up of three proteins: STE-related adaptor (STRAD), mouse protein 25 (MO25), and LKB1.

Live Cell Research calls AMPK a “master switch” because this enzyme regulates several key systems within the body, such as increasing cellular energy, stimulating the oxidation of fatty acids and glucose transport, and more.

While the exact details are far outside the scope of this review (and they might make you go cross-eyed), the thing about AMPK is that some fairly specific conditions need to be present for the enzyme to be activated—the primary method of which is muscle contraction (i.e. working out).

Once AMPK is activated, there is some clinical evidence showing it may increase blood supply to muscles, help transport glucose (simple sugars), boost fatty acid metabolism (thereby creating more energy for the cell), and more.

What if you don't want to hit the gym to boost your AMPK levels? Can you accomplish the same thing by popping a couple of LA-3 pills?

Will LA-3’s Ingredients Boost Your AMPK Levels?

According to their supplement label, LA-3 contains the following ingredients:

Of these, WebMD indicates that 30mg daily of gynostemma may be effective for reducing cholesterol. So, at 450mg per dose, LA-3 delivers significantly more than this, although there doesn’t seem to be any clinical evidence indicating that increased gynostemma consumption results in more obvious benefits.

Is ActivAMP a Clinically Proven Ingredient?

Important note: The gynostemma pentaphyllum found in LA-3 is part of a proprietary ingredient named ActivAMP, which is manufactured by a company named Gencor Pacific.

According to their website, in a 12-week randomized clinical trial, ActivAMP was shown to decrease body fat mass and body fat percentage, reduce body weight and BMI, and shrink the total abdominal area.

To see the results for ourselves, we reached out to Gencor Pacific and obtained some of their clinical evidence for ActivAMP, which consists of seven different trials. Here is just a handful:

  • A 2013, 23-week randomized, double-blind, placebo-controlled clinical trial that concluded ActivAMP might be useful for treating obese individuals.
  • A 2012, 8-week study that showed mice “decreased body weight gain, liver weight, and blood cholesterol levels with AMPK activation in the soleus muscle.”
  • A 2011 study showing the ingredient may be effective for improving glucose and lipid metabolism.
  • A 2008 study showing that ginsenosides may have an anti-obesity effective. All results were obtained via cells in a controlled laboratory setting.

Now, we’re not medical experts (which is why we rely on authoritative sites to determine whether or not an ingredient is classified as “effective”), so we have no reason to doubt the findings in Gencor Pacific’s research.

Just keep in mind that results obtained through experiments conducted on mice and cells don’t necessarily mean you, as a human, will experience the same thing.

And even if these studies were conducted on humans, it would require dozens (or perhaps even hundreds) of reproducible, double-blind, placebo controlled, peer reviewed studies before if could be considered “proven” to work as advertised.

For more about this topic, be sure to read Think That Clinical Study Is Legit?

LA-3’s Other Ingredients

Moving on, WebMD also tells us that 1,000mg daily of quercetin (commonly known as jiaogulan) might help alleviate prostate pain and inflammation. But at just 100mg per dose, there doesn’t appear to be enough in LA-3 to provide these benefits.

Finally, WebMD indicates that berberine might also be effective at reducing cholesterol, as well as blood sugar levels in diabetes patients.

Bringing It All Together Regarding LA-3’s Ingredients: What Can You Realistically Expect?

As we can see, there are clearly some clinically validated benefits for the ingredients found in LA-3.

However, according to authoritative websites like WebMD, there doesn’t appear to be enough clinical evidence showing that these ingredients—whether on their own or in combination—can elevate AMPK levels.

Granted, there is some promising research related to AMPK, although most clinical studies have been conducted on mice (including one of the studies for ActivAMP).

So, based on what we learned after reaching out to Live Cell Research, there seems to be little clinical proof that these same protocols will work in humans.

Are There Any Potential Side Effects From LA-3?

Despite the limited evidence showing that these ingredients can boost AMPK levels, the good news is that they’re generally considered safe.

However, WebMD notes that gynostemma pentaphyllum “can cause some side effects such as severe nausea and increased bowel movements.” Also, it’s unknown if taking quercetin for more than 12 weeks is considered safe.

How much will you pay for LA-3’s three-ingredient formulation?

How Much Does LA-3 Longevity Activator Cost?

Live Cell Research’s LA-3 supplement is available in the following quantities:

  • 1 Bottle: $46.99
  • 3 Bottles: $117
  • 6 Bottles: $216

Like all Live Cell Research products, LA-3 comes with a 90-day refund policy, less S&H charges. To request one, you'll need to contact customer service at (844) 650-5933 or support@LiveCellResearch.com.

Based on these prices, are LA-3’s customers generally satisfied with what they get for their money?

What Can We Learn From LA-3 Customer Reviews?

Since conducting our original research, 19 LA-3 customers have written about their experience on HighYa, giving the supplement an average rating of 3.8 stars.

Here, most compliments seem to reference effective results, including reduced belly fat, increased energy, improved weight loss, and decreased appetite and cravings.

On the other hand, as is the case with many other nutritional supplements, the most common customer complaint about LA-3 seems related to ineffective (or non-existent) results. In fact, even among those who experienced positive results, several noted that it took several weeks to achieve any effects and that they were fairly mild.

Granted, all of this relates to LA-3 as a product. What about the company who manufactures it?

Who is Live Cell Research? Are They Reputable?

Live Cell Research is based out of Southern California, where they manufacture a line of popular supplements, including Niagen, Cerastim, Midogen, Vital Stem, and more.

Overall, the company’s supplements seem to come with mostly positive online customer reviews, with common compliments citing effective results. On the flip side, common complaints reference failure to work/achieve results and difficult customer service experiences.

Unfortunately, the company wasn’t listed with the Better Business Bureau at the time of our research. Let’s bring it all together, shall we?

Is LA-3 the Right Nutritional Supplement for You?

On the one hand, with many of the Live Cell Research products we’ve written about in the past, authoritative websites like WebMD note that the clinical evidence supporting many of the company’s claims is lacking.

On the other hand, many customers claim to have experienced positive results with the company’s supplements—LA-3 included—clinical evidence notwithstanding.

Does this mean you should hand over your hard-earned money for Live Cell Research’s LA-3 supplement? Like any other nutritional supplement, what works fantastically for you might be a total flop for someone else, and vice versa.

The seemingly good news is that Live Cell Research offers a 90-day refund window on all of their products, which you can take advantage of if you’re not fully satisfied. Just keep in mind that you'll be out a few dollars for return shipping and handling.

Finally, if you type the phrase “AMPK supplement” or “AMPK activator” into your favorite search engine, you’ll be met with dozens of supplements making many of the same claims as LA-3, including Life Extension.

Sure, they might not be formulated exactly like LA-3, but their claims (and general lack of clinical support) are much the same.

Were you pleased with LA-3’s performance? Or, do you feel it was a waste of money? Whatever your experience, we want to hear about it—be sure to leave a review below!

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242 Customer Reviews for LA-3 by Live Cell Research

Average Customer Rating: 4.2
Rating Snapshot:
5 stars: 122 4 stars: 78 3 stars: 17 2 stars: 7 1 stars: 18
Bottom Line: 87% would recommend it to a friend
Showing 1-11 of 242
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  • 1 out 1 people found this review helpful

    LA-3

    This product has improved my energy and I feel that also maybe my digestion. In the mornings, if I don't eat something right away after I wake up, my stomach goes crazy. With LA-3, It soothes it and I can wait and do my exercises before I eat, so maybe it will help me loose weight!

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 1 people found this review helpful

    Still Testing

    I've been using LA-3 for just under a month now. I've lost a few pounds, maybe 5-7 pounds, and I haven't really changed my eating habits. I've also lost about an inch around my belly. I have noticed that my appetite is more "in check". I don't feel hungry a lot and I feel satisfied quicker while eating, so I'm not eating as much (no seconds). I'll have a better idea of the effectiveness of the product in another month or so, but seems to be helping so far.

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 2 people found this review helpful

    Personal Experience

    After watching the video of LA-3, I got to thinking that a lot of what they were saying was true. So I said what have I got to lose but money and I have lost that before on things that didn't work. After it came in, I began taking it the next day. I started noticing more energy and little by little, weight began coming off. Nothing major but slow, the way it should be. I'm on my second bottle now and love it.

    Bottom Line: No, I would not recommend this to a friend

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  • 1 out 1 people found this review helpful

    Excellent product

    I have had a wonderful experience with LA-3 . The first week I took two tablets in the morning and I felt good during the whole day. I was more alert no down time as far as getting sleepy during the day. I am more energetic and more at peace. Thank you for coming up with a great product.

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 1 people found this review helpful

    LA-3

    Really amazing product. I was buying for my husband who experienced significant body changes and abdominal fat loss in the first week of using LA-3.

    He will be using the product in the future and I hope to have an even better result overall.

    Thank you

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 1 people found this review helpful

    Just Try It

    I am just finishing up my first bottle of LA3. Because I started several new supplements and one new medication at around the same time, I cannot be totally sure what has made the difference but it seems that my clothes are fitting better.

    I am afflicted with many medical ailments but it seems that the most annoying are weight issues and Lipidema (the disease they call fat) and Lymphedema which cause swelling and tenderness. Since starting this product, it seems as if my legs are less fluid filled, my torso is less tender and rigid which I attribute to a change in the fat cells. If you are not familiar with Lipidema, it is when the fat cells expand to the point of being like and overfilled water balloon and become painful to the touch. These fat cells do not reduce with dieting. I have noticed a change for the better since starting LA3 and hope to see more results in the coming months.

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 1 people found this review helpful

    LA-3

    • Texas,
    • Apr 24, 2017

    First week, I used to have to take a morning nap, now I can stay awake. I've had trouble losing weight, but I noticed some inches lost on my upper torso, on the sides. I was surprised.

    Energy has improved, went camping and didn't feel exhausted afterward. Able to exercise longer. I'm 61 years old and I'm still trying to see how it goes.

    Small changes but I have to admit, something is going on.

    Bottom Line: Yes, I would recommend this to a friend

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  • 2 out 2 people found this review helpful

    LA-3 works great for me

    I started taking LA-3 on March 25, 2017. I "cold turkeyed" my one coke a day and started drinking sparkling water. I gave up my sugar addiction and gave up bread. I was so desperate to lose 100 lbs. My doctor would do NOTHING for me except preach exercise. Grr, exercise, good if you can do it. I can't, I have fibromyalgia, osteoarthritis, and have to use a walker and cane as my left hip is full of arthritis and I can't even step on it. I'm 66 years old and feel 166; so stiff and sore and in pain all the time.

    I have not been hungry and have absolutely NO cravings. I have energy back and I feel there is hope for me. This product works for me. I been telling all my family and friends that you need this. It is SO amazing to me. "Wow" is all I can say. Wow, it works for me!

    I wanted my old active life back, and I am going to make it back to 166 lbs with this product's help. I am 266 lbs now and have lost 16 lbs. I have been eating fish and chicken, and drinking lots of water with apple cider vinegar in it.

    I wish you all the good luck as I have been having with LA-3.

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 1 people found this review helpful

    Great product

    I have been on LA-3 for three weeks and have lost three inches off my waist and 26 pounds. My energy level is way up and I couldn't ask for anything more.

    Bottom Line: Yes, I would recommend this to a friend

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  • 4 out 5 people found this review helpful

    After two month's use

    This product has made a big difference in my health and weight control efforts. Both were like a "yo-yo" up and down all the time.

    With the start of LA-3, everything stabilized. I feel better all the time. I rarely feel hungry. I don't over eat. Slowly the fat is dropping off, and I can feel it as my range of motion increases. I have a ways to go to be down to a healthy weight.

    With LA-3 I think I will finally have the stable weight loss and better health to return to a more active lifestyle.

    Bottom Line: Yes, I would recommend this to a friend

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  • 5 out 5 people found this review helpful

    Awesome results!

    • Oneida, NY,
    • Apr 22, 2017

    I am in my first month, and I feel a big difference in my body. I have more energy, and my cravings for salty foods have diminished. I am able to work out more, lift weights and do cardio. I can see my belly is shrinking as well. I am able to follow a healthy diet because I feel more motivated. I can't wait to see the changes next month!

    Bottom Line: Yes, I would recommend this to a friend

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