About Nucific Deep Cell Activator
Nucific Deep Cell Activator is a nutritional supplement that promises to activate the AMPK enzyme, leading to “dramatically” improved energy, clearer thinking, decreased abdominal fat, and a “stronger, healthier” body.
To accomplish this, Nucific tells us you’ll need to take two capsules of Deep Cell Activator with a glass of water, with or without food. Within the first 7 days of regular use, the company claims you’ll begin feeling increased energy and reduced appetite, while you could experience reduced abdominal fat within a couple weeks.
Then, after about a month of taking Deep Cell Activator, Nucific tells us that anyone can become less forgetful and begin experiencing improved overall health and strength.
While Nucific promises that each of their ingredients are subject to third-party laboratory testing to ensure the highest quality, you’re here because you want to know if they’ll deliver on the company’s claims. We’ll get to that shortly, but let’s first take a closer look at AMPK.
What Is AMPK? How Does It Work?
Discovered in the late 1970s, AMPK (also known as 5' adenosine monophosphate-activated protein kinase) is an enzyme that that’s found in a number of tissues throughout the body, including the liver, brain, and skeletal muscle. According to Wikipedia, AMPK serves a variety of key roles in the body, including regulating the cellular uptake of glucose, “the β-oxidation of fatty acids and the biogenesis of glucose transporter 4 (GLUT4) and mitochondria.”
Specifically, they note that, “Upon activation, AMPK increases cellular energy levels by inhibiting anabolic energy consuming pathways (fatty acid synthesis, protein synthesis, etc.) and stimulating energy producing, catabolic pathways (fatty acid oxidation, glucose transport, etc.).”
Because of this, some research on mice has shown that inhibiting AMPK can lead to reduced appetite and weight loss, or when activated, to increased appetite and weight gain. It’s also been shown to increase blood flow to muscles during exercise, extend the life of roundworms, boost fatty acid metabolism, and even treat some aspects of diabetes and cancer.
On the flip side, overproduction of AMPK has been linked with Alzheimer’s disease.
In a nutshell, while AMPK certainly seems to play several key roles in the body, there’s still a lot the medical community doesn’t understand about the enzyme, and much of the clinical evidence (especially related to improved exercise performance) is contradictory.
Nonetheless, will can of Deep Cell Activator’s ingredients boost AMPK levels or provide any other kinds of benefits?
Are Deep Cell Activator’s Ingredients Effective for Boosting AMPK?
According to the supplement’s label, Deep Cell Activator contains only three ingredients:
- Gynostemma Pentaphyllum (Jiaogulan) leaf extract 450mg
- Quercetin dihydrate 100mg
- Berberine HCl 100mg
Note: Since we’re not medical professionals here at HighYa, we generally rely on WebMD’s summarization of the clinical evidence to let us know whether an ingredient is “effective,” “possible effective,” and so forth for a given claim.
With this said, jiaogulan contains a moderate amount of Ginsenosides (one of the active ingredients thought to provide Panax ginseng with many of its benefits), although the medical community doesn’t fully understand all of its active compounds. As a result, WebMD lists 30mg of Jiaogulan daily as possibly effective for reducing cholesterol levels, although they indicate there’s insufficient clinical evidence showing that it’s effective for any other conditions.
Quercetin is a flavonoid commonly found in many different plants and foods, including red wine, green tea, apples, ginkgo biloba, and more. WebMD lists 500mg of quercetin daily as possibly effective for reducing prostate pain and inflammation, but not for any other conditions.
Similarly, WebMD indicates that 1,000 to 1,500mg of berberine per day may help slightly reduce blood sugar levels in diabetics and reduce high blood pressure.
Outside of this, however, we didn’t encounter any body of clinical evidence indicating any of these ingredients will help boost AMPK levels, or provide any of the other benefits promoted by Nucific.
Will Deep Cell Activator’s Ingredients Cause Any Side Effects?
In most cases, WebMD indicates that if you experience any side effects at all from Deep Cell Activator’s ingredients, it likely won’t be anything worse that mild digestive upset.
However, they note that in some instances, jiaogulan can cause severe nausea and increased bowel movements.
How Much Does Deep Cell Activator Cost?
Nucific offers Deep Cell Activator in the following packages:
- 1 Bottle: $46.99 + $4.95 S&H
- 3 Bottles: $117 + free S&H
- 6 Bottles: $216 + free S&H
Regardless of which option you choose, each is a one-time payment, without any recurring monthly charges.
All Deep Cell Activator purchases come with a 90-day money back guarantee, less S&H. In order to request one, Nucific’s customer service department can be reached at (888) 679-5520 or email@example.com.
Are There Any Online Customer Reviews for Deep Cell Activator?
Deep Cell Activator was too new at the time of our research to have garnered any online customer feedback, although one of the company’s other supplements, BIO X4, had a 4.2-star average rating here on HighYa based on 237 reviews. Most of the compliments referenced positive results, including improved digestion, boosted energy, reduced appetite, and more.
On the other hand, common complaints referenced no results and customer service issues. Whenever a complaint was left, the company seemed to respond quickly.
Obviously, this is a completely different supplement, so we’re not saying you’ll experience the same with Deep Cell Activator. However, it can help provide you with a broader perspective of the overall situation.
From a company perspective, Nucific was founded in 2015 and is based out of Los Angeles, CA. The company manufactures several other supplements, including CL X3, Digest, Krill Oil, and a probiotic.
Are There Other AMPK Supplements Like Deep Cell Activator?
Type the phrase “AMPK supplement” into any search engine, and you’ll quickly find dozens (perhaps even hundreds) of other supplements that promise to deliver many of the same benefits as Deep Cell Activator (including one from Life Extension). While many of these feature different formulations than Deep Cell Activator, you’ll find much of the same if you search only for the ingredient “Gynostemma Pentaphyllum.”
Now, we already discussed the clinical evidence for many of these ingredients above, and the same holds true whether they’re found in Deep Cell Activator or the supplement’s competitors. But from a price perspective, some of these third-party AMPK-boosting supplements can be purchased for as little as $15.
One more thing before wrapping up: who is Dr. Amy Lee?
What Do We Know About Dr. Amy Lee?
Dr. Amy Lee is a triple-board certified bariatric physician based out of Los Angeles, CA, who has appeared in numerous publications and seems to maintain a positive online patient reputation. Prior to becoming a physician, Dr. Lee earned her medical degree at the University of Illinois, Urbana-Champaign, and attended a Fellowship in Clinical Nutrition and Weight Management at the University of Southern California.
Today, Dr. Lee specializes in nutritional therapy and her integrative healthcare approach focuses on obesity and chronic inflammation. She is also the founder of the MDietician brand and the Performance LA health center in downtown Los Angeles.
What Kinds of Benefits Can You Expect From Deep Cell Activator?
We didn’t test Nucific’s Deep Cell Activator supplement ourselves, which means we ultimately have to rely on WebMD’s summary of the available clinical evidence. And from this vantage point, they indicate there isn’t enough to indicate that any of the supplement’s ingredients will reliably boost AMPK levels, or provide benefits other than slightly reducing blood sugar and cholesterol.
What does this mean for you? You work hard for your money, so you get to decide where it’s spent. But based on the clinical evidence, it appears you might get much more bang for your buck by speaking with your doctor about energy, blood sugar, cholesterol, or other concerns, versus purchasing a bottle of Deep Cell Activator.
On the other hand, Nucific seems to stand behind Deep Cell Activator with a 90-day refund policy if you feel like giving it a try, although you’ll be out a few bucks in return shipping.
Did Deep Cell Activator deliver on its promises? Tell us about your experience by writing a review below!