About Vital Stem

Vital Stem is a nutritional supplement that promises to boost stem cell levels in your body and reverse many of the side effects of aging. And by working at the cellular level, the company tells us that Vital Stem could help you experience improved cognitive function, enhanced joint and muscle strength, and increased longevity.

According to the manufacturer, all you have to do is mix one scoop of Vital Stem with a 12-oz glass of water and drink first thing in the morning on an empty stomach. From there, we’re told the supplement’s blend of five potent, fully bioavailable ingredients will get to work, without any known side effects.

You probably noticed that there are a whole lot of science-y words floating around on the Vital Stem website, so let’s make things easy by breaking it all down into everyday language. This way, you can make as informed a decision as possible.

First? Let’s lay a solid foundation by talking about stem cells.

Stem Cell Basics

If there was ever a “holy grail” of aging, stem cells would probably fit the bill. But why?

In humans, these cells possess the amazing ability to “develop into many different cell types in the body during early life and growth,” and well as to “serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive.”

However, not all stem cells are created equal. Embryonic stem cells can become any other type of cell within the body (a state known as pluripotent), while adult stem cells are limited to their original tissue type. Also, embryonic stem cells can be grown in the lab fairly easily, while adult ones still can’t be grown in a culture.

Here are a couple simplistic examples: A pluripotent stem cell remains undifferentiated and can turn into anything; a heart cell, a liver cell, a red blood cell, and so forth. On the other hand, an adult stem cell—from the lungs, for instance—can only become a cell of the same tissue type.

The Problem With Stem Cells

Despite the potential held by stem cells, they’re not perfect. How?

First, although embryonic stem cells could have the potential to massively improve modern medicine (including anti-aging), there’s a big ethical debate going on. After all, these cells are obtained from 3-5-day old embryos (technically called blastocysts, which are a collection of about 150 individual cells), destroying the embryo in the process.

Second, even if this ethical dilemma was removed by focusing only on adult stem cells (more about this next), the next problem becomes the delivery method. In other words, stem cells are extraordinarily fragile and can’t survive for long outside of a very controlled environment. On top of this, even if these cells were engineered to be hardier, simply taking a stem cell contained supplement wouldn’t translate into any meaningful benefits.

With all of this said, is it possible to boost stem cell production in the body, but without using any stem cells in the first place?

The Big Question: Is It Possible to Boost Stem Cell Production—Without Stem Cells?

According to Live Cell Research, the ingredients contained in Vital Stem will help boost the “proliferation of adult stem cells, the “master cells” of your body that repair damage to your muscles, skin, organs and brain.” We’re also told they “have been shown to boost proliferation of human CD34+ and CD133+ cells, which are essential to your body’s cellular function.”

What does the available clinical evidence have to say about this?

Although the science is new, based on our own online research, it does appear that some types of drugs can stimulate the human body to increase stem cell production, versus the old method of “injecting patients with stem cells from donors, embryos or stem cell banks.” After all, even the CD34 and CD133 referenced on the Vital Stem website, while only used in bone marrow transplants and treating some types of brain tumors, still require injection.

Outside of these very specific drugs, however, there seems to be limited publically available clinical evidence (see also NIH’s PubMed) indicating that stem cell levels can be reliably boosted using natural ingredients commonly found in supplements.

What about Vital Stem, though? Does it contain a unique blend of ingredients shown to meaningfully boost stem cell levels and deliver other real-world results? And if so, does the manufacturer provide any evidence to support their claims? Let’s take a look.

Will Vital Stem’s Ingredients Boost Stem Cell Levels?

Reading through the product label on Vital Stem’s website, the supplement contains the following ingredients:

According to Wikipedia, l-leucine is an amino acid that has the “capacity to directly stimulate muscle protein synthesis” and to “slow the degradation of muscle tissue by increasing the synthesis of muscle proteins in aged rats.”

However, they go on to note that, “comparative studies are conflicted.” In other words, until more clinical evidence is available, we can’t say for sure that it can regularly provide these benefits. But one thing we can say is that we didn’t encounter any clinical evidence during our research indicating l-leucine can boost stem cell production in the human body.

As far as green tea, it contains a substance known as epigallocatechin gallate (EGCG) that’s been widely studied for dozens (perhaps even hundreds) of medical conditions.

According to WebMD, after analyzing much of the available clinical evidence, they list green tea as “likely effective” for genital warts and high cholesterol, and “possibly effective” for things like clogged arteries, high/low blood pressure, osteoporosis, and more. On the other hand, they don’t indicate anything related to stem cells.

WebMD also notes there isn’t enough evidence showing carnosine can provide any benefits in humans and the blueberry powder is only for taste.

Despite what we just learned, the Vital Stem website references 3 different studies to support their claims:

  • A 2010 study conducted by Moscow State University that found carnosine might reduce oxidative stress without side effects, and was even “successfully used to treat patients after brain stroke or patients with Parkinson disease.”
  • A 1999 Finnish study that found leucine supplementation might stimulate muscle protein synthesis and prevent degradation (similar to what we discussed above). However, the study only referenced leucine’s benefits in relation to “exhaustive aerobic exercise” and “those participating in intensive training”—not for aging.

Even then, the study concludes by noting: “Caution must be paid when interpreting the limited number of studies in this area since, in many studies, leucine has been supplemented as part of a mixture of BCAA. Consequently, further research into the effects of leucine supplementation alone is needed.”

  • A 1999 Australian study that showed the longevity of cultured human fibroblasts was extended when exposed to l-carnosine.

As the second study noted, one (or even a handful) of clinical trials doesn’t necessarily mean that a supplement is “proven” to work. In other words, it takes an entire body of repeatable, peer-reviewed clinical evidence before something can be classified as proven.

For more about this topic, be sure to read Think That Clinical Study is Legit?

But here’s the thing: Even if Vital Stem’s ingredients were proven to be effective, all but one are part of a proprietary formulation, so we don’t know exactly how much of each it contains or if it’s enough to provide any results.

While WebMD indicates that none of these ingredients will boost stem cells, do they mention anything about side effects?

Are There Any Potential Side Effects From Taking Vital Stem?

The positive news is that, if you experience any side effects at all from using Vital Stem, they probably won’t be any worse than mild digestive upset.

However, green tea contains a relatively small amount of natural caffeine, which could cause rapid heartbeat, nervousness, and other side effects if you’re especially sensitive to stimulants.

Finally, WebMD notes that there isn’t enough known about some ingredients—such as l-carnosine—to fully understand any potential side effects you might experience.

Now, how much will a bottle of Vital Stem cost you?

How Much You’ll Pay For Vital Stem

Vital Stem is available in the following quantities:

  • 1 Bottle: $46.99 plus $3.95 S&H
  • 3 Bottles: $117 plus free S&H
  • 6 Bottles: $214.27 plus free S&H

All Live Cell Research products, including Vital Stem, come with a 90-day refund policy, less S&H charges. In order to request one, you’ll need to call (844)-650-5933.

Given the seemingly low amount of clinical evidence supporting its ingredients, are Vital Stem’s customers finding that it provides a solid value?

What’s Everyone Saying In Their Vital Stem Reviews?

Since originally researching the supplement, four HighYa readers have left their feedback for Vital Stem, giving it an average rating of 4.8 stars. Here, most common compliments seem to revolve around reduced pain; improved energy, stamina, and sleep, and boosted recovery.

In fact, the only complaint listed was that one customer didn’t really care for the taste.

From a company perspective, Live Cell Research had an average rating of 2.8 stars here on HighYa, based on 33 reader reviews (as of 9/23/16). These were split almost evenly between 1 and 5-star ratings. What can we learn from them?

While some customers claimed to have experienced results from their products and appreciated the helpfulness of their service department, common complaints for the company seemed to revolve around failure to work, difficult customer service (primarily problems obtaining refunds and long response times), as well as long shipping times.

What about some of the company’s other supplements? Niagen, arguably the company’s most popular product, had a similar 3-star rating here on HighYa, with 77 reader reviews. Midogen had a higher 4.3-star average rating and LA-3 a 2.5-star rating, while Cerastim and Advanced Adult Probiotic didn’t have any reviews at the time of our research.

Considering all of this, is Live Cell Research’s Vital Stem supplement right for you?

The Bottom Line About Vital Stem

We had to cover a lot of ground to get to this point, but the reality is that when it comes to Vital Stem, the bottom line is fairly simple: With the exception of leucine, WebMD tells us that there isn’t sufficient clinical evidence supporting the company’s claims.

So, in our opinion (after all, we’re consumers too!), if you’re looking to get most of the same benefits as Vital Stem but without the relatively high price, your money might be better spent purchasing a standalone leucine supplement, many of which can be found for as little as $10. As always, just be sure to speak with your doctor first!

But if you feel like rolling the dice on Vital Stem, it’s positive that Live Cell Research provides a 90-day refund policy. Just keep in mind that you might be out a few bucks in S&H charges if you’re dissatisfied and decide to process a return.

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37 Customer Reviews for Vital Stem

Average Customer Rating: 4.4
Rating Snapshot:
5 stars: 18 4 stars: 16 3 stars: 2 2 stars: 1 1 stars: 0
Bottom Line: 97% would recommend it to a friend
Showing 1-11 of 37
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  • 1 out 2 people found this review helpful

    My experience with Vital Stem

    I have been trying to take this product at least twice a day. One important detail is that it is one scoop to a twelve-ounce glass of water. Keeping to this detail the solution will be sweeter and easier to drink.

    I am sure any improvements in my body health are subtle, but I believe in the product and will continue to take it.

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 2 people found this review helpful

    Helped my memory

    I stayed with it and took the whole container until it was empty. The taste is not the greatest, but I got used to it. I noticed after a couple of weeks that things were improving. What I really noticed, and why I was taking it, was for my memory lapse. I am 65 years old and I was having trouble when going into my pantry and forgetting what I was there to get, be it paper products or food items that I keep there.

    I noticed this got way better as I kept taking Vital Stem. There was less time for me to think what I was there for, and became less and less of that happening to me. I really think it works for that. I've gotten so much better in the memory department.

    Bottom Line: Yes, I would recommend this to a friend

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  • 2 out 3 people found this review helpful

    Excellent formula!

    This product has an excellent formulation, but the taste is not that great.

    Bottom Line: Yes, I would recommend this to a friend

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  • 2 out 3 people found this review helpful

    One month review

    I have been using the T-cell product for one month now, and though I have not noticed a different experience, I purchased three months worth to give a chance to work with my system. Would like to give another review in two more months.

    Bottom Line: Yes, I would recommend this to a friend

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  • 4 out 5 people found this review helpful

    Arthritis

    • Arizona,
    • Jan 11, 2017

    I am just finishing up my fifth container of Vital Stem and have found my arthritis pain is much better. Actually, it got much better in the first month, but I wanted to read reviews from others before purchasing more.

    I did notice that one other person had the same problem I had, that out of all 6 of my containers, I only had 22 days worth of product. I don't know if I just received a batch that was shorted by mistake, or if this is their modus operandi. I did notify the company, but it went nowhere, so I'm still not sure I will buy from them again.

    Yes, I would recommend only if they got a full 30 days per container.

    Bottom Line: Yes, I would recommend this to a friend

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  • 4 out 5 people found this review helpful

    This is truly a phenomenal product and I am so grateful that I found it

    Vital Stem surpassed my expectations!

    I suffer from clinical depression and have been taking Prozac for 14 years. And I know it works because my doctor tapered me off of it several years ago, and approximately six weeks after I was completely off of it, the depression hit me like a ton of bricks! So obviously, my doctor put me back on the Prozac, to help control my depression, but that's all it was doing.

    I experienced the benefits of Vital Stem right away! It was as though this fog was lifted and what was left in its place was an overall sense of well-being.

    This is a feeling that I have not had in a very long time, so now, my mission is to get everyone I love to start taking Vital Stem!

    Bottom Line: Yes, I would recommend this to a friend

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  • 4 out 5 people found this review helpful

    Back pain reduced

    • Rio Rancho, NM,
    • Dec 31, 2016

    I'm not sure what I expected, but I believe Vital Stem is helping my back. I have chronic back pain in my lower back, and when I take Vital Stem, the pain is almost not noticeable.

    What would make Vital Stem better is if it was in a pill form, not powdered because the taste is not too good.

    Bottom Line: Yes, I would recommend this to a friend

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  • 3 out 3 people found this review helpful

    Felt improvement in a long standing open wound condition

    Three years ago I had an unexpected bout in the hospital. Emergency procedures were required to save my life. I had received multiple blood transfusions as a result. Shortly after discharge from the hospital, I developed two open, weeping wounds which persisted until I started the Vital Stem regimen. One wound dried up and healed over within a week. The other is still somewhat active, but easily scabs over now. I'm quite hopeful that it will also eventually disappear as well.

    Bottom Line: Yes, I would recommend this to a friend

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  • 9 out 10 people found this review helpful

    Amazing results.

    • Rome, GA,
    • Dec 27, 2016

    I'm 49 years old and have a very active lifestyle but I have had joint pain and stiffness for over 15 years from playing football as a kid, weight lifting, and over 6 years in the Infantry. This product has relieved me of the pain and inflammation in my joints. I've taken over the counter meds for years with temporary results. Vital Stem has been a real blessing for me. I've used Vital Stem for 2 months and I'm convinced this product does what it says it will do.

    Bottom Line: Yes, I would recommend this to a friend

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  • 4 out 5 people found this review helpful

    Excellent

    I put Vital Stem in a 500ml of Fiji water and drink it. I actually enjoy the taste. I started taking it in June and I definitely noticed an improvement in how I felt and slept. I have ordered my second 6 month supply. I did run out and didn't want to spend the money, but after taking a month off, I ordered again and am back on.

    Bottom Line: Yes, I would recommend this to a friend

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  • 7 out 7 people found this review helpful

    Better Than Expected

    I am 71 years old and I still work full-time as a California Correctional Officer in one of our state prisons. I began my present career at age 62, so I still have a few years to go before retirement. I purchased a 6-month supply of Vital Stem as a hedge against "premature" aging, and to strengthen my immune system so I can work well into my 70s. I have been taking your product every morning for almost 2 months. I feel an extra charge of energy during the day that lasts until the end of my shift at 10:30 PM, and beyond, for my 1-hour drive home after work. Many days I skip the morning cup of coffee because I already feel wide awake after my daily dose of Vital Stem mixed with 16 oz. of purified room temperature water.

    My overall strength and stamina have improved over the past 45 days which I owe to your product, as well as another new supplement in my regimen. I also dropped 12 lb. in the past month and a half -- from 215 to 203, without doing any additional exercise, which was an unexpected benefit.

    In my view, there are only 2 negatives about the product: It doesn't mix well with water. I frequently have to stir it 200 - 300 times to get it to dissolve all the way instead of it clumping up. The second thing is, I believe the fruit flavoring could be improved, considerably. But, maybe it's just my taste buds. All-in-all, I believe Vital Stem is contributing to my overall good health, and helping me reach my goal of working full-time for another 8 - 12 years.

    Bottom Line: Yes, I would recommend this to a friend

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Showing 1-11 of 37

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