a-Drenal Reviews - Addresses Your Fatigue and Stress?

By Derek Lakin
HighYa Staff Published on: Oct 21, 2018

Using a comprehensive formulation of organic adrenal tissue and adaptogenic herbs, RLC Labs advertises that their doctor-approved a-Drenal supplement can help promote healthy glandular function and combat the side effects of adrenal fatigue.

Together, they tell us customers could expect effective support from stress-induced symptoms, normalized cortisol and blood sugar levels, and a calm, balanced physical and mental energy.

Can you realistically expect to experience all of the benefits advertised by a-Drenal's manufacturer? Is there a useful methodology for deciding which supplements might deliver maximum value, before handing over your money?

In this brief article, we’ll take a look at the clinical support for a-Drenal’s ingredients, potential side effects, price, and how to buy an adrenal fatigue supplement to help keep you informed.

What Role Do the Adrenal Glands Play?

The adrenal glands sit atop each kidney and are responsible for producing hormones like androgens (male sex hormones, such as dehydroepiandrosterone (DHEA) and testosterone), glucocorticoids (e.g., cortisol), mineralocorticoids (aldosterone), and catecholamines (e.g., adrenaline, noradrenaline, dopamine).

In some instances, whether due to genetic mutations, tumors, infections, problems in other glands, or certain medications, MedlinePlus reports the adrenal glands can over or under-produce these essential hormones.

Consequently, this can lead to a wide variety of potential side effects, including obesity, low or high blood pressure, weakness, moodiness, shorter than average height, and weight loss, to name just a few.

What about the adrenal fatigue referenced on the a-Drenal website?

According to the Mayo Clinic, “adrenal fatigue is a term applied to a collection of nonspecific symptoms, such as body aches, fatigue, nervousness, sleep disturbances and digestive problems. The term often shows up in popular health books and on alternative medicine websites, but it isn't an accepted medical diagnosis.”

With these essential details, how does a-Drenal work inside the body?

Taking a Closer Look at a-Drenal’s Ingredients

The supplement facts label listed on the RLC Labs website reflects the following ingredients for a-Drenal:

  • Pantothenic Acid 250 mg
  • Cordyceps sinensis Rhizome Powder 400 mg
  • Adrenal Tissue (from Organic Bovine) 250 mg
  • Ashwagandha Root PE 150 mg
  • Rhodiola rosea Root PE 100 mg
  • Siberian Eleuthero Root PE 100 mg
  • Korean Ginseng Root PE 100 mg
  • Astragalus membranaceus Root PE 100 mg
  • Epimedium grandiflorum Herb Powder 100 mg
  • L-Theanine 100 mg
  • Ginger Root PE 50 mg
  • Beta-Sitosterol 40 mg

Since the HighYa staff doesn’t have a professional background in medicine, chemistry, or pharmacology, we rely on the cumulative clinical evidence reported by sites like WebMD and the Natural Medicines Database when reporting whether or not an ingredient is effective for a given claim.

And according to these sites, taking 600 mg per day of a specific ashwagandha root extract (KSM66, Ixoreal Biomed) is listed as possibly useful for improving symptoms of stress. a-Drenal contains only 150 mg per dose.

Taking anywhere between 200 and 400 mg of Panax (Siberian, Korean) ginseng per day is listed as possibly effective for improving “abstract thinking, mental arithmetic skills, and reaction times in healthy, middle-aged people but not in young adults.”

These same sites report insufficient clinical evidence supporting RLC Labs’ claims for a-Drenal’s remaining ingredients.

Could a-Drenal’s Ingredients Cause Side Effects?

For most of a-Drenal’s ingredients, the Natural Medicines Database, WebMD, and Examine.com report temporary, mild side effects (if any), such as nausea and digestive upset.

Pantothenic acid is an excellent example of this: "The recommended amount for adults is 5 mg per day,” they tell us. “Even larger amounts (up to 10 grams) seem to be safe for some people. But taking larger amounts increases the chance of having side effects such as diarrhea.”

And since a-Drenal contains 250 mg of pantothenic acid per dose (25X higher than the upper daily limit), the chances of this occurring could be greater.

The long-term safety of ingredients like ashwagandha, rhodiola, and theanine is reported as unknown, and Healthline emphasizes, “Taking adrenal extracts could have some unintended consequences [… since they] can make your adrenal glands stop working. If that happens, it can take your glands months to start working correctly again after you stop taking the supplements. “

Furthermore, they conclude with, “The FDA doesn’t oversee vitamins and nutritional supplements, so there’s no guarantee that the label on adrenal extracts will match the contents.”

Related: History of Dietary Supplements: When Did They Start & How Are They Regulated

How Much Does a-Drenal Cost & Where Can You Buy?

While the RLC website indicates that a-Drenal is “only available through a healthcare professional,” we found it sold through several online retailers such as Amazon, Natural Healthy Concepts, PureFormulas, and EvenBetterNow.com. Prices were usually between $30 and $40.

The refund policy available to you (if at all) will depend on the retailer you purchase from. If you need to reach RLC Labs for customer support regarding a-Drenal, their line is 877-797-7997.

What Are Customers Saying in Their RLC Labs a-Drenal Reviews?

On Amazon, we encountered 130 combined customer reviews for the a-Drenal supplement, who had given it an average rating of 4.4 stars.

Compliments often cited improvement in side effects related to adrenal fatigue (brain fog, boosted energy, balanced mood), while the relatively few complaints frequently involved no results and side effects like general illness and nausea.

How Can You Choose Between a-Drenal and Competing Adrenal Fatigue Supplements?

Even if you recently started investigating dietary supplements formulated to address adrenal fatigue, a quick online search will reveal that a-Drenal is up against hundreds of potential competitors.

Many of these also include several of the same ingredients, with prices that can vary widely between less than $15 to well over $60. How can you make a more informed decision?

As usual, start by talking with your doctor before purchasing any dietary supplement. They can discuss your needs and expectations, and might be able to recommend options based on your specific diagnosis.

With this said, ConsumerLab recommends that these options should be taken with extreme caution. This is because:

“While some of the ingredients [found in adrenal supplements] have individually been shown to reduce fatigue or symptoms of stress, there is currently little evidence that "adrenal support formulas" do the same or improve adrenal gland function.

Additionally, an analysis of popular adrenal support supplements on the market found that all contained small amounts of thyroid and steroid hormones, which could potentially cause adverse effects or interfere with blood test results.”

Furthermore, to expand upon what Healthline reported above, the Endocrine Society’s Hormone Health Network adds, “If you take adrenal hormone supplements when you don’t need them, your adrenal glands may stop working and become unable to make the hormones you need when you are under physical stress.”

“When these supplements are stopped,” they tell us, “a person's adrenal glands can remain “asleep” for months. People with this problem may be in danger of developing a life-threatening condition called adrenal crisis.”

Should You Place an Order for RLC Labs’ a-Drenal Dietary Supplement?

HighYa’s goal is to present an overview of information related to a product or service, so you can quickly find what you need to make an empowered decision. Our goal is not, on the other hand, to tell you how to spend your money.

With this said, we think the facts presented by sites like the Natural Medicines Database, WebMD, Healthline, and MedlinePlus speak for themselves:

Adrenal fatigue isn’t a medically recognized condition (so there’s also no recognized treatment plan), and there’s little-to-no clinical support that the ingredients found in adrenal fatigue supplements will deliver on manufacturers’ claims.

Balancing this out, though, is the fact that a-Drenal seems to come with a competitive price, as well as mostly positive online customer feedback. Just make sure that you verify the retailer’s S&H charges and return policy before placing your order, so you can get your money back if it doesn’t meet your expectations.

>> Read next: Before Buying a Dietary Supplement, Follow These Steps to Understand its Claims

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