About Appethyl

By HighYa Research Team
Published on: Feb 6, 2015

Extracted from spinach, Appethyl claims to be a 100% natural, patented, and clinically tested green powder that helps reduce hunger, decrease cravings for unhealthy foods, and to promote “significant” weight loss.

In order to accomplish this, Appethyl is claimed to use pure spinach that’s been carefully treated to free the thylakoids trapped inside, which can then be added to smoothies using the ingredients of your choice. When taken daily, Appethyl is claimed to help you stay satisfied, reduce the urge to eat for pleasure, and to provide “acute and long-term appetite suppression.”

Originally marketed in Sweden but only recently available in the U.S., Appethyl claims to be gluten free, vegan-friendly, and made with non-GMO ingredients, while resulting in no side effects. Each sealed bag of Appethyl contains enough individual, 5-gram packets for 30 days, each of which include the following ingredients:

  • Vitamin A 350IU
  • Vitamin K 65mcg
  • Folic Acid 20mg
  • Calcium 150mg
  • Iron 6mg
  • Lutein 1,400mcg
  • Zeaxanthin 40mcg

How Does Appethyl Claim to Work?

According to Appethyl’s manufacturer, the supplement works over 4 steps:

  1. The thylakoids (more about this next) in Appethyl mix with dietary fats in your stomach.
  2. Upon interacting, these thylakoids cover the fats as well as your stomach wall.
  3. Higher than normal levels of undigested fats pass into the lower part of the digestive tract.
  4. Because less digestion is occurring and decreased levels of fat are being absorbed, your body will release appetite-suppressing hormones into your bloodstream, helping you to feel satisfied, despite absorbing less fat.

A diagram from Appethyl's webiste of how thylakoids are claimed to increase satiety and decrease hunger cravings.

The company claims that Appethyl requires fat to work best, so you should add a tablespoon of olive oil, grapeseed oil, or sunflower oil to your food if it’s especially low in fat.

Doesn’t it seem like some new weight loss fad comes around a few times per year? But invariably, they end up not performing as advertised? But is Appethyl the latter, or is it the real deal? Consider the following:

What Are Thylakoids? 

According to the Appethyl website, “A thylakoid is a membrane-bound compartment inside chloroplasts and cyanobacteria found in spinach and other leafy greens.” In plants, thylakoids “are the site of the light-dependent reactions of photosynthesis;” e.g. where plants convert light into energy.

In humans though, the thylakoids contained in Appethyl are claimed to “help reduce hunger and cravings by giving the body's own satiety signals time to work, thereby helping you make healthy food choices and stick to a healthy diet.” Unfortunately, these beneficial thylakoids pass through our digestive system untouched, but the manufacturer of Appethyl claims to have created a way to free them and use them to your benefit.

Sounds good, but is there any scientific validation for these claims?

Is Appethyl Clinically Tested?

According to the supplement’s website, Appethyl’s thylakoids were studied under 6 animal trials, which we were able to locate by searching NIH’s PubMed for “thylakoids and satiety.”

Most recently, a 2014 study from the Department of Experimental Medical Science at Lund University in Sweden, found that the “addition of green-plant membranes as a dietary supplement once daily induces weight loss, improves obesity-related risk-factors, and reduces the urge for palatable food.” However, it’s important to note that “waist circumference, body fat and leptin" remained the same between the control group and the group given thylakoids.

An earlier 2013 study from the same university suggested “that the dietary addition of thylakoids could aid efforts to reduce food intake and prevent compensational eating later in the day, which may help to reduce body weight over time.”

In fact, all 6 of the published studies related to thylakoids came from the same department at the same Swedish university, which might have been funded by the company now selling Appethyl in the U.S. While businesses-sponsored research is nothing new, and there’s nothing necessarily wrong with it, this fact is worth noting nonetheless.

With this said, all the available research for the thylakoids contained in Appethyl seems to point to it as an effective appetite suppressant. However, as GreeneyEdGuy summed up nicely, “there are many factors that affect how much food is consumed at a meal,” including volumetrics and social cues. In other words, appetite is one of the many reasons that people eat, therefore suppressing appetite may not work equally well for all individuals.

Are Customers Really This Excited Over Appethyl?

Despite the fact that DietSpotlight reviewed Appethyl as far back as February 2013, there weren’t many online customer reviews for the supplement at the time of our research. Amazon.com did have 4 customer reviews (as of 2/5/15) for Appethyl averaging 4 stars, with common compliments citing reduced appetite and decreased craving for carbohydrates and sweet foods. 

Interestingly, nearly all the mini-reviews and forum comments we read for Appethyl were glowingly positive, which could mean that either 1) the supplement is about to take the dieting world by storm, or 2) not all of these reviews are genuine.

With this said, Appethyl appears to be manufactured (at least here in the U.S.) by GreenPolkaDotBox.com, who holds a C+ rating with the Better Business Bureau, despite having just 1 complaint (as of 2/6/15). However, it appears the company failed to respond to the complaint. 

Appethyl Pricing & Refund Policy

Appethyl can be purchased in one of two ways:

  • As a 7-day trial for $7.95 S&H.
  • As a one-time purchase for $49.95 plus S&H.

7-day trials for Appethyl appear to only be available through affiliates who earn commissions from each sale they refer, while the one-time purchase appears to only be available through the GreenPolkaDotBox website.

If you choose the trial option, after it ends, the manufacturer will charge your card $44.95 for the full price of the product. Then, you’ll also be enrolled in the company’s autoship program, which means you’ll continue receiving a 30-day supply of Appethyl once per month, and you credit card will be charged $44.95 plus $7.95 S&H each time.

Affiliate purchases also appear to include a free recipe book, although for more recipe ideas, you can search online for “Appethyl recipes” and you’ll receive dozens of results.

Outside of the trial, Appethyl comes with a 30-day refund policy, less S&H charges.

To cancel you trial, stop your autoship enrollment, or request a refund, you’ll need to contact customer service at 844-748-2669.

Can Appethyl Help You Lose Weight While Feeling Satisfied?

Chopping to the point: At this point, it’s too early to tell. This is because there are very few online reviews for the product, and nutritional supplements manufacturers are notorious for overstating the benefits of their products.

However, it appears that the thylakoids contained in Appethyl have some positive clinical research behind them, although we’ll have to wait and see if these results translate out of the lab, and into the real world.

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