About Biotic 365

By Derek Lakin
HighYa Staff
Published on: Aug 20, 2017

If you’re suffering from food cravings, bloat or other embarrassing digestive issues, or having difficulty managing your weight, the Biotic 365 from United Probiotics probiotic supplement promises to deliver relief by bringing your gut flora back into balance.

The supplement works using a formula of entirely natural ingredients that are flash frozen and packed into kosher, allergen-free, vegetarian capsules, which we’re told allows it to stay fresh and effective for years, without refrigeration.

By taking one capsule with the first meal of the day (or whenever is best for you, really), the supplement’s website indicates you could start seeing results within 30-60 days, with potentially considerable results after eight weeks. Finally, they claim it’s safe to use, regardless of your age or any dietary restrictions you have.

You’re reading this because you want to know if Biotic 365 really can help control your appetite, reduce bloating, and promote smoother digestion. So let’s dive right in and lay a solid foundation.

What Are Probiotics and Do You Need to Take Them?

In Probiotics 101, we discuss the fact that beneficial bacteria (otherwise known as probiotics) play a big role in our overall health. Specifically, they’re a highly important component of digestion, waste elimination, and immune function.

Not all bacteria are beneficial, though. Sometimes, whether due to excessive stress, a poor diet, lack of sleep, insufficient exercise, a recent illness, a round of antibiotics, or a whole host of other conditions, the ratio of ‘good’ to ‘bad’ bacteria can shift out of balance.

As a consequence, this can lead to side effects like inflammatory bowel disease (IBD), bloating, gassiness, increased instances of illness, and even reduced energy.

Fortunately, beneficial bacteria can be reintroduced to the gut by eating foods like kefir, yogurt, sour milk, and kimchee. And if you’re looking for perhaps the most targeted boost, supplements like Biotic 365 can deliver many different strains all at once.

Specifically, which ones will you find here?

Taking a Closer Look at Biotic 365’s Ingredients

Biotic 365’s label indicates it contains a total of 25 billion colony-forming units (CFU) of 19 different probiotics.

For ease of reference, we’ve subdivided them below by genus (i.e., Lactobacillus; think of this as a large family) and species (i.e., salivarius; think of this as similar individuals).


Lactobacillus is one of the most popular genera found in probiotics supplements and makes up the majority of the strains found in Biotic 365:

  • Lactobacillus salivarius
  • Lactobacillus rhamnosus
  • Lactobacillus bulgaricus
  • Lactobacillus reuteri
  • Lactobacillus casei
  • Lactobacillus fermentum
  • Lactobacillus plantarum
  • Lactobacillus acidophilus
  • Lactobacillus gasseri
  • Lactobacillus paracasei
  • Lactobacillus brevis

While some strains may work better for very specific conditions (e.g., reducing atopic dermatitis in children, helping modulate brain activity), sites like the Natural Medicines Database, WebMD, and Examine.com indicate that Lactobacillus, in general, may help improve digestion, address irritable bowel syndrome, and boost immune function.

Saccharomyces, Enterococcus, & Streptococcus

The following standalone strains are found in Biotic 365:

  • Saccharomyces boulardii
  • Enterococcus faecium
  • Streptococcus thermophilus

According to WebMD, Saccharomyces boulardii may help address various types of diarrhea, acne, and Heliobacter pylori infections, while E. faecium and S. thermophilus may be effective for reducing antibiotic-induced diarrhea.


Like Lactobacillus, Bifidobacterium is a very popular genus, with some strains that deliver highly specific benefits (e.g., reducing radiation-induced diarrhea). In general, though, these same authoritative websites indicate there’s lots of clinical evidence it can help address constipation and urinary tract infections, decrease total cholesterol, and reduce IBS symptoms.

Here’s what’s in Biotic 365:

  • Bifidobacterium lactis
  • Bifidobacterium longum
  • Bifidobacterium bifidum
  • Bifidobacterium anamalis
  • Bifidobacterium breve

Proprietary Blend

Prebiotics Proprietary Blend 200mg: Inulin (Chicory Root Extract), Fructooligosaccharides

Inulin is a natural energy source produced by plants that contains high amounts of fiber, but is low in calories. Healthline tells us that it can help control blood sugar, keep you feeling full longer, potentially reduce cancer risks, and also act as a food source for probiotic bacteria.

Similarly, the fructooligosaccharides in Biotic 365 are a type of non-digestible carbohydrate that acts as a prebiotic (food source) for probiotic bacteria.

Could Biotic 365’s Bacteria Strains Cause Side Effects?

These same sites indicated that most people don’t experience meaningful side effects when using probiotics. And for those who do, it often isn’t much worse than bloating and distention that typically goes away within two to three days.

However, if you have an immune system disorder, are pregnant or breastfeeding, or have an infant with short bowel syndrome, you’ll definitely want to discuss Biotic 365—or any other probiotic supplement, for that matter—with your doctor beforehand.

How Much Does Biotic 365 Cost?

At the time of our research, what you paid for Biotic 365 largely depended on which of the supplement’s sites you purchased from. For example, a one-time order on their 3horriblefoods.com site was priced as follows:

  • 1 Bottle (30 capsules): $38.95
  • 3 Bottles: $116.85 ($38.95 per bottle)
  • 6 Bottles: $219 ($36.50 per bottle)

Alternately, if you decided to subscribe to the company’s membership program, you’d automatically receive monthly shipments and pay the following:

  • 1 Bottle: $33.95/mo
  • 3 Bottles: $104.95/mo ($34.98 per bottle)
  • 6 Bottles: $195/mo ($32.50 per bottle)

Finally, if purchased directly through the United Probiotics website, bottles were priced at:

  • 1 Bottle: $49
  • 3 Bottles: $139 ($46.33 per bottle)
  • 6 Bottles: $219 ($36.50 per bottle)

These prices included free shipping and a 90-day guarantee, less S&H. The 3horriblefoods offer also included a bonus copy of Dr. Sachar's revolutionary diet program.

If you need to request a refund or end your recurring membership program, customer service can be reached at support@unitedprobiotics.com.

How do these prices compare?

How to Choose Your Next Probiotic Supplement

Even just a cursory online search or stroll through your nearest pharmacy’s supplements aisle will reveal that the market is currently flooded with probiotic formulas competing in the same space as Biotic 365.

Some of these contain just one or two strains, while others feature dozens. Strength-wise, you’ll find some provide just millions of colony forming units (CFU; basically, individual bacteria cells), while others number 30 billion or more.

Price? We found some that cost as little as $5 and others that topped the list at $70 or more, putting Biotic 365 somewhere near the middle.

In our probiotics buyers guide, we help you narrow down this immense number of options by asking the following questions:

  • Is there a full supplement facts label listed, including dosages and CFU?
  • Does the supplement contain a bunch of additional ingredients, or only probiotic strains?
  • Speaking of which, how many strains and CFUs does the supplement have compared to the competition?
  • What’s the company and the product’s online customer reputation? What’s everyone saying in their reviews? Do you find any recurring themes?
  • Does the price seem more or less in line with the competition? Based on our research, customers may not get meaningfully more for their money by spending on higher priced probiotic supplements.
  • Is there a mandatory trial or autoship program involved?

Let’s take a closer look at how all of this applies to Biotic 365 as we wrap things up.

Our Final Thoughts About Biotic 365

The Positive:

Biotic 365 comes packed with 25 billion CFU of 19 different bacteria strains that sites like WebMD, Examine.com, and the Natural Medicines Database indicate could provide a range of digestion and immune-related benefits. They also don’t need to be refrigerated to remain effective.

Pro tip: Just keep in mind that, based on our time spent researching dozens of different probiotic supplements, we haven’t encountered any evidence directly linking higher CFU count with meaningfully better results.

Not only is it priced somewhere near the middle of the pack, but it also comes from a company that has a clear online presence and who offers a 90-day refund policy on their supplements, which should be more than enough time to figure out if it works for you. And there are no trials or mandatory autoship programs involved.

Finally, based on the appearance of her image on one of Biotic 365’s websites, it seems that the supplement is endorsed by Dr. Su Sachar, a board certified gastroenterologist who operates a popular practice in Torrance, CA.

Things to Think About

Although there’s a lot of reported clinical support associated with these probiotic strains, it’s always a good idea to talk with your doctor about any digestion or immune symptoms you might be experiencing. They’ll be able to properly diagnose you and then recommend the appropriate treatments.

Money saving tip: But even if your doctor recommends a probiotic supplement in general, or Biotic 365 specifically, it’s important to point out that if you purchase the three-bottle option through the 3horriblefoods.com website, it’s actually more expensive per bottle than the single option.

Another consideration is that other than their main website, we didn’t encounter anything else online about the company, including through the Better Business Bureau. There also weren’t any customer reviews available.

In the end, though, with the company’s 90-day refund policy, you might not have much more to lose than return S&H charges if you’re dissatisfied with Biotic 365’s performance.

» Related: Probiotics for Kids: A Parent’s Comprehensive Guide

Read 6 Biotic 365 Customer Reviews and Complaints

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Average Customer Rating: 3.0
Rating Snapshot:
5 star: 3 4 star: 0 3 star: 0 2 star: 0 1 star:  3
Bottom Line: 50% would recommend it to a friend
Showing 1-6 of 6
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  • 8 out 8 people found this review helpful
    Updated review

    Still waiting for refund

    • By Kenneth P.,
    • New Jersey,
    • Jan 21, 2019
    • Verified Reviewer

    I brought their check to the investigation department at my bank. The bank wants to three-way call with the investigation unit, the tellers, the managers, now the fraud department got involved and will be contacting the company. I'm still waiting for them to refund me, but the bank said the check was not legit. We actually called the bank, which was posted on the check, and they said that routing number does not exist. So buyer beware, I'll add a little more when I get a chance. Hopefully, I will get my money back. Thank you.

    Bottom Line: No, I would not recommend this to a friend

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    • Previous review
    • Jan 18, 2019

    Refunds for returns.

    The product came quickly. When I realized that being a cancer patient I shouldn't take it with any proper information on the bottle, I called immediately for a refund, and finally, they sent it after multiple calls and emails to get them to send me a return label, it took weeks. Finally, I received it.

    I sent both products back and somehow the post office had left them a notice but they never picked it up. I rescheduled the package for them. Then they said they couldn't give me the money back on my credit card, there was a problem on their side with the Visa (funny, they still take orders), so they're are going to send me a check. I reported it to my bank and credit card company, and my bank to the investigation bureau to see whether it's good, they will investigate the check and find out whether this $158 will be placed back into my account without me getting scammed. Fifth Third Bank from Delaware NetBus Inc which is the authorized signature stamped. I should include the pictures; it doesn't look legit to me so I'll give you a follow-up. Thank you for taking the time to read this. At the moment I'm not happy with the product, it didn't have the proper information for my oncology doctors who were a little skeptical, so I refrained from taking the product. Thank you, have a great day.

    (read moreread less...)

  • 4 out 6 people found this review helpful

    Not necessarily the product, but the company.

    • By Dave S.,
    • Oklahoma,
    • Nov 9, 2018
    • Verified Reviewer

    I didn't have any luck taking the Probiotic, but I will say this about the company. When I explained to them, that it just wasn't working for me, they immediately informed me that I would be getting my money back, due to their guarantee. Within two-three weeks, I had received my credit due without any hassles.

    Bottom Line: Yes, I would recommend this to a friend

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  • 12 out 14 people found this review helpful

    Worked for me!

    • By Penny B.,
    • Florida,
    • Jun 22, 2018
    • Verified Reviewer

    I had a 90-day supply that I recently ran out of. I was having severe issues with IBS with diarrhea, and nothing seemed to help. I started taking the Biotic 365, and within a month my IBS symptoms got markedly better, and I also noticed way less gas than I previously had. I also lost a few pounds without even trying. I made the mistake of trying another probiotic that was given rave reviews online. Needless to say, my symptoms are coming back slowly. I WILL be reordering the Biotic 365.

    Bottom Line: Yes, I would recommend this to a friend

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  • 19 out 20 people found this review helpful

    Doesn’t work

    • By Shirley M.,
    • Washington,
    • Jun 3, 2018
    • Verified Reviewer

    I have tried this as suggested. It does not work. It made me very sick and bloated. I tried for over two months, just kept getting worse.

    Unfortunately, they would not give me a refund. I wanted to return four unopened boxes, but they would not let me return, saying my 90 days was up. I will not recommend this product to anyone.

    Bottom Line: No, I would not recommend this to a friend

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  • 18 out 18 people found this review helpful

    Not effective

    • By Marilyn W.,
    • Madison, WI,
    • May 30, 2018
    • Verified Reviewer

    I purchased a three-month supply as was recommended. I took the capsule every morning with a full glass of water, as directed. I have not noticed any change with the exception of increased gas/bloating. I will not re-order.

    Bottom Line: No, I would not recommend this to a friend

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  • 10 out 11 people found this review helpful

    Losing weight

    • By Iva Morey,
    • Sidney, NY,
    • Mar 27, 2018
    • Verified Reviewer

    I have been taking Biotic 365 since December 29th, 2017. Since that time I have lost 11 pounds. I am delighted with the results. I have tried to lose by counting calories and doing the point system, but I have always failed. Although I am not losing weight fast, I have been healthier and I feel better.

    Bottom Line: Yes, I would recommend this to a friend

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