What is Esotique XV Plant Stem Cell Therapy?

By HighYa Research Team
Published on: Jan 20, 2017

Esotique XV Plant Stem Cell Therapy is a soft, silky anti-wrinkle treatment that uses a blend of four active ingredients, along with flower and essential oil extracts, to deliver moisturization and reduce the signs of aging.

Chamonix tells us that Esotique XV Plant Stem Cell Therapy is absorbed without causing sensitivity or clogged pores, and it’s made without mineral oil, petroleum byproducts, and pharmaceutical preservatives.

Even within the world of luxury skincare products, it’s clear to see that XV Plant Stem Cell Therapy is a high-priced product. The question is—and likely why you landed on this article: Can you expect to get a lot of value for the money?

Chamonix is a big name in the online-only beauty industry, but does that mean their Esotique XV Plant Stem Cell Therapy is right for you? That’s exactly what we’ll help you figure out here.

What’s the Difference Between Human & Plant Stem Cells? Any Anti-Aging Benefits?

In humans, stem cells are undifferentiated; they have the ability to develop into many different types of cells. Adult stem cells can only become another cell of the same tissue type (muscle, for example), while embryonic stems cells can become any other type of cell in the body.

Human stem cell research is in its relative infancy, although it holds promise for addressing many serious medical conditions, including cancer, birth defects, spinal cord injury, and stroke.

Stem cells are also commonly used to test new medications. Other stem cell-based therapies may help grow tissue for organ transplantation, treat burns, heart disease, diabetes, and arthritis.

While plant cells function meaningfully different than ours, those in plants play the same role as stem cells in humans; they’re undifferentiated and can become other types of cells. Both human and plant stem cells are extraordinarily fragile as well, making them difficult to include in most OTC beauty creams.

In other words, by the time they reach you, most of the stem cells in these creams would perish.

With this said, Genucel doesn’t specifically claim that Esotique XV’s Plant Stem Cell technology actually contains any plant stem cells. In fact, other than that it contains ingredients derived from Swiss apples, they don’t tell us anything else about its formulation.

Truth In Aging tells us there is some clinical evidence that a stem cell extract derived from the Uttwiler Spätlauber apple may reduce crow’s feet, although the study wasn’t independent and was conducted on a small group of 20 subjects.

In the end, they state, “The whole thing is hooey and has as about as much basis in reality as that other Swiss apple myth, the legend of William Tell.” As a company, Genucel doesn’t provide any evidence to support their claims for Esotique XV, either.

What about the remainder of Esotique XV’s ingredients? What kind of results might you realistically experience from them?

How Effective Are Esotique XV Plant Stem Cell Therapy’s Other Ingredients?

Again, we’re not provided with a complete list of ingredients for Plant Stem Cell Therapy, although we’re told it contains the following:

  • Peptides
  • Hyaluronic acid
  • CoQ10
  • Enzyme Activation™ group (vitamins B3, B6)

A Quick Discussion About Peptides

In a nutshell, peptides are just small proteins. The amino acids contained in peptides are essential for an enormous number of basic functions like cellular regeneration, muscle and tissue maintenance, and hormone production.

But what can the topical application of peptides do for your skin?

First, peptides are too big for your skin to absorb, so the amino acids they contain aren’t processed by your body. However, there are four different types commonly found in skincare products that can work without passing through your skin:

  • Neurotransmitter Inhibitors – These inhibit the release of acetylcholine, a neurotransmitter that signals muscles to move. As a result of decreased movement, the appearance of wrinkles if temporarily reduced. A popular example is Botox Cosmetic.
  • Signal Peptides – These help stimulate the production of collagen and other proteins in the skin, often resulting in firmer, fuller-looking skin.
  • Carrier Peptides – These don’t provide any direct benefits, but they help trace elements like copper and magnesium penetrate the skin.
  • Enzyme Inhibitors – These interfere with enzyme reactions, some of which can degrade structural proteins, helping to keep skin younger looking.

Are there some peptides that can deliver skin benefits? Clearly. Which of these is contained in Esotique XV Plant Stem Cell Therapy? What kinds of results might they reasonably deliver? Without additional information, there’s no way to know.

What Is Hyaluronic Acid?

As a molecule, hyaluronic acid (HA) can hold a great deal of water. In fact, just one gram of the substance can hold up to six liters of H2O!

Like peptides, HA can't penetrate the skin, but because of its water-attracting power, it can work as an effective moisturizing ingredient and help plump skin.

CoQ10 & Your Skin

Similar to hyaluronic acid, CoQ10 is also a naturally occurring substance in the body that acts as a powerful antioxidant to help cells produce energy and maintain health.

There’s quite a bit of clinical evidence indicating that CoQ10 supplementation could help improve the condition of skin, especially if you’re deficient. However, we didn’t encounter this same level evidence for the topical application of CoQ10.

The Important of B Vitamins

The specific B vitamins contained in Esotique XV Plant Stem Cell Therapy (B3, or niacin, and B6, or pyridoxine) can provide a variety of treatments high blood pressure and cholesterol, lung cancer, PMS, osteoarthritis, and type 1 and 2 diabetes.

Unless you’re deficient, however, authoritative websites didn’t reference any topical benefits for otherwise healthy individuals.

How Much Does Esotique XV Plant Stem Cell Therapy Cost?

Esotique XV is available in the following quantities:

  • 2 oz Jar: $110
  • 4 oz Jar: $198
  • Buy One 2 oz, Get Another 50% Off: $165
  • Buy One 4 oz, Get Another 50% Off: $297

All orders over $79 come with free shipping.

Genucel products, Esotique XV Plant Stem Cell Therapy included, come with a four-month return or exchange policy, less S&H. There are no processing fees.

Important note: This does not apply to product received through the Preferred Customer Program. Here, only exchanges or company credit are permitted, with the exception of your initial sign up order.

To request a refund, Genucel’s customer service department can be reached at 800-754-6211.

Despite the mixed clinical evidence (according to authoritative websites) for many of Esotique XV’s ingredients, do customers feel like they’re getting a solid return on their investment?

Do Esotique XV’s Customers Think the Price Is Worth It?

On the Chamonix website, XV Plant Stem Cell Therapy had mostly positive feedback, with common compliments referencing improved skin condition, boosted moisturization, younger looking complexion, and quick absorption.

While there weren't any specific complaints, a couple of potential customers asked about a complete list of ingredients, without a response from the company.

Outside of two reviews on Amazon, we didn’t encounter any additional customer feedback on third-party websites.

There, one customer complained that the cream didn’t seem to be any more effective than less expensive ones they’d used in the past. Another noticed a small improvement in their skin, but wasn’t sure it was worth the high price.

The HighYa team has reviewed a handful of the manufacturer’s other products, including Genucel, Genucel Dark Spot Corrector, and Chamonix T-Gen.

Overall, the product line had an average rating of 1.4 stars from readers, with many complaints referencing no results, high prices, and side effects (swelling, dry skin).

Note: These are common complaints among many other stem-related related products we’ve reviewed, such as Stemologica, as well as those from brands like Life Extension and Dr. Al Sears MD.

Several also complained that they didn’t appreciate being signed up for an autoship program or being charged a restocking fee (as mentioned earlier, this last practice is no longer in place).

Clearly, we’re not drawing a direct relationship between these other products and Esotique XV Plant Stem Cell Therapy. But it can help provide a clearer view of the overall picture, which is what we’re all about.

Should You Invest In a Jar of Esotique XV Plant Stem Cell Therapy?

Let’s be honest: At $37 to $55 per ounce (depending on the package you choose), it’s easy to consider Esotique XV Plant Stem Cell Therapy an investment in your beauty. But is it one that will pay dividends, or will it be like throwing money out the window?

Ultimately, there’s no way to know without giving it a try. While authoritative websites indicate there’s slim evidence that Esotique XV’s ingredients will deliver the significant improvements touted by Chamonix, the good news is that the manufacturer seems to stand behind their product with a four-month return policy.

On top of this, many customers provide positive feedback, although this is limited outside of the Chamonix website.

In the meantime, we emailed the company and requested a full list of Esotique XV Plant Stem Cell Therapy’s ingredients, along with the specific peptides it contains and any clinical proof supporting the manufacturer’s claims. We’ll be sure to update this article as soon as a response is received.

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