What is Make Sense 27 and How Does It Work?
Make Sense 27 is a daily dietary supplement produced by Habit Of. The brand claims its concentrated formula of EPA and DHA omega-3 fatty acids and vitamin B12 and D3 works to support your health in many ways.
According to the brand’s promotional material, these supplements are formulated with essential nutrients that many people are unknowingly deficient in. They claim that the human body can’t produce omega-3’s so supplementation is necessary to ensure you take in adequate amounts, and that vitamin D3 and B12 are two of the most common nutrient deficiencies worldwide.
By taking two daily supplements, they state that you’ll benefit from premium-grade ingredients optimized for easier absorption to boost your health. Do these claims hold up to scientific scrutiny? We’ll answer that question by looking closer at the ingredients.
Make Sense 27's Ingredients: Efficacy and Side Effects
The Habit Of website highlights that Make Sense 27 contains nothing but high-quality, essential nutrients that are free of pesticides, PCBs, heavy metals, and GMOs. The active ingredients include omega-3 fatty acids in the form of fish oil (both EPA and DHA), other omega-3 fatty acids, vitamin B12, and vitamin D3.
We scoured the research on Consumer Labs, a leading provider of independent test results of health and nutrition facts, to see what they deliver for your health. Let’s walk through the findings, ingredient by ingredient. Note that all dosage levels are given for a recommended serving of two capsules.
Vitamin B12 (100 mcg)
Make Sense 27 sources their B12 from methylcobalamin, one of the two most preferable forms it can take from a human health perspective. This compound is critical for normal nerve cell functioning and works with folate and vitamin B6 to reduce the amount of homocysteine in your blood, a compound associated with elevated risks of heart disease. Severe deficiency can lead to nerve damage and anemia. There’s also preliminary evidence that supplementing with vitamin B12 can improve your mood and reduce anxiety symptoms.
You don’t need much vitamin B12 to stay healthy, as adults over age 14 need just 2.4mcg per day, making deficiency rare in everyone but the elderly who may struggle to absorb it from food. This means that a recommended dosage of Make Sense 27 delivers over 250 times the minimum daily requirement.
As we learned from Healthline, high doses of B12 are generally considered safe because it is a water-soluble vitamin. Saying that, some studies have linked mega doses to skin problems like acne and rosacea, though the research focused on injections rather than oral supplements.
There’s evidence that taking large daily doses of B12 can help counter the effects of a deficiency faster. However, while the risk is small with excess consumption, there’s little evidence that doses of B12 above daily requirements offer benefits for those who aren’t deficient.
Fish Oil (2400mg):
According to the product website, Make Sense 27 contains premium grade omega-3 fatty acids secured from fish found off the Atlantic surrounding Iceland.
The supplement’s nutrition information lists fish oil as a separate ingredient from EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), though these are the two omega-3 fatty acid compounds that fish oil contains. As the label shows that the supplements contain 880 mg of EPA and 660 mg of DHA, it’s unclear what constitutes to other 1,300 mg of fish oil per serving.
Consumer Lab reports that taking fish oil supplements that contain EPA and DHA offers wide-ranging health benefits, including preventing cancer, maintaining muscles mass, improving mental health, and treating inflammatory disease. They are also used to support heart health, as they can improve artery functioning and lower the risk of heart attacks for those with heart disease.
The suggested standard dose is between 300 and 500 mg of each per day, though many studies with positive results looked at significantly higher dosage levels—sometimes as high as 4,000 mg.
It’s also noteworthy that there isn’t any reliable evidence that taking fish oil supplements will prevent heart attacks and related cardiovascular issues in otherwise healthy people, and that those who are already eating one or two servings of fish a week aren’t likely to get additional benefits from taking a daily supplement.
Vitamin D3 (1000 IU)
Considered both a vitamin and a hormone, your body needs vitamin D3 to absorb calcium properly. The most common intake method is through sunlight exposure, though it’s also possible to take it in through food or in supplement form.
Getting adequate amounts of vitamin D works to prevent and treat osteoporosis, and there’s some evidence it may also reduce your risk of certain cancers, including breast, skin, colon, and pancreas. Other studies challenged this connection, and most of the studies referenced on Consumer Labs seem to show that vitamin D is less effective if not taken with calcium.
Daily requirements vary by age, but adults should work to keep their intake between 600 and 9,000 IU. Beyond this upper limit, the Mayo Clinic states that vitamin D can lead to a toxic buildup of calcium in your blood called hypercalcemia, which can lead to nausea, vomiting, bone pain, and kidney problems.
However, the amount necessary to trigger these problems is equivalent to taking 120 Make Sense 27 supplements a day for several months in a row. At regular doses, your risk is low.
There are also several inactive ingredients in these supplements that act as fillers and stabilizing agents, including gelatin, glycerol, natural lemon oil, and non-GMO natural mixed tocopherol. Nothing on this list caught our attention from a health perspective.
Regarding safety information, Habit Of states that certain people should consult with their doctor before taking Make Sense 27. These include pregnant or lactating women, hypoglycemics, diabetics, and those on medication for other health issues.
How Much Does Make Sense 27 Cost?
Habit Of sold Make Sense 27 for $39.34 at the time of writing, plus $4.45 for shipping.
You’ll receive sixty mint-and-lemon-flavored capsules per canister, which the company states are packaged with 100% recycled materials. This provides you with a thirty-day supply of supplements, assuming you follow the company’s suggestion that you take one supplement twice a day at meal times.
Make Sense 27’s return policy states that you can return unopened items within 30 days of delivery for a full refund. The company will pay the return shipping costs only if the return is a result of an error on their end like a damaged product.
Any purchase that has been opened don’t automatically qualify for returns or refunds, but the company will consider them on a case-by-case basis if you contact them at firstname.lastname@example.org.
Our View: Is Make Sense 27 Worth It?
Now to pull this information together; do we think Make Sense 27, well, makes sense? As we consider whether Make Sense 27 will work as promised, the first step is to discern precisely what these promises are. Unfortunately, our experience is that the product website is vague at best about what this supplement will deliver.
We also think it’s worth pointing out that we couldn’t find any customer reviews of Make Sense 27 at the time of writing. In fact, the only mention of this supplement online is the product website, Instagram, and a small Facebook page. This makes it difficult to know what the customer experience is like, whether purchasers received their orders as advertised, and if they thought the supplements improved their health after using them for a few months.
While the product website is light on details, we did learn some interesting information about its ingredients.
What stood out on our end is that most of the ingredients in this supplement (vitamin B12, fish oil, and vitamin D3) are only beneficial in supplement form if you are already deficient in them. That’s most likely to be a concern for strict vegans and those who stay out of the sun. So, while Healthline confirms that the company is correct that B12 and D3 deficiencies are two of the most common worldwide, they still pose minimal health risks for most people.
There’s not much harm from surpassing your daily dose requirements of these nutrients, but there’s little advantage either. And, at $43.79 for a monthly supply, you’ll be paying approximately $1.50 per day if you take two capsules as recommended. We think that’s on the high end for a fish oil supplement, especially for one that leaves such large knowledge gaps in the ingredients list.
For these reasons, we don’t think there’s necessarily anything wrong with Make Sense 27, but that you might be able to do better. We suggest scoping out other brands that have a larger internet footprint so you can read customer reviews and get more precise ingredients information. A smart way to begin your search is with this article: A Beginner’s Guide to Buying the Right Nutritional Supplement.