MoveMD Review - Can It Provide Joint Pain Relief?

By HighYa Research Team
Updated on: Dec 18, 2019

Medically Reviewed by Anthony Dugarte, M.D., C.S.C.S & Jason Reed, Pharm.D.

What Is MoveMD?

MoveMD is a supplement intended to fast-acting relief for joint pain in the knees and back through a combination of five vegan, gluten-free ingredients.

“MoveMD™ is a special combination of the latest in joint health science to help you wake up each morning and hit the ground running,” the product’s website claims.

The company that sells this product is 1MD. It sells at least nine different supplements. 1MD works with four board-certified doctors to create their supplements. Dr. Adam Kreitenberg, a board-certified rheumatologist, is the doctor who specifically endorses MoveMD.

In our review of this supplement, we will discuss how it works (including instructions for taking it), the scientific evidence for its ingredients’ efficacy, possible side effects and MoveMD’s pricing and return policy.

How MoveMD Works: How to Take It and the Claims

The directions for use are simple. Take one capsule in the morning with a glass of water on an empty stomach. The site says you can take the capsule whenever you’d like but in the morning is the suggested time.

Each bottle of MoveMD contains 30 capsules, so one bottle will last you a month.

Once that capsule is inside your body, 1MD says it releases its five main ingredients into your system:

  • ApresFlex boswellia serrata (100 mg)
  • Zanthin natural astaxanthin (2 mg)
  • Type XIV eggshell membrane collagen (100 mg)
  • Type II chicken collagen (280 mg)
  • Hyaluronic acid (25 mg)

The collagen in each capsule will be to reduce joint pain after seven days, 1MD claims, while it will take about two months for the boswellia serrata to alleviate knee discomfort. The two-month timeframe is something we’ll discuss in the scientific efficacy section, as it’s based on a study published in 2006 in the Journal of Neurosurgery.

Additional claims about conditions for which MoveMD provides help include:

  • Lymphocyte proliferation
  • Joint comfort support
  • Joint flexibility and strength support
  • Cartilage synthesis support
  • Anti-inflammatory support

MoveMD Ingredients: What They Are and Evidence

MoveMD’s claims focus on two things: what its ingredients can do and how fast they can do them. We will examine both in this section.

ApresFlex Boswellia Serrata

Boswellia serrata is commonly known as frankincense. Researches over the past 20 years or so have investigated this plant’s effect on rheumatoid arthritis and osteoarthritis, as well as other conditions unrelated to the claims MoveMD makes about it.

One of those studies, a 2006 article published in the Journal of Neurosurgery, says that a group of people suffering from arthritis-driven knee pain experienced a “statistically significant improvement in arthritis of the knee.”

The caveat is that participants took around 1,000 milligrams per day, whereas MoveMD’s daily dose provides 100 milligrams.

Similar extracts were proven to be effective at pain reduction in 100mg doses, however. This was corroborated in a study comparing the pain threshold in those taking 125mg of Boswellia serrata when compared to placebo.

“ApresFlex” refers to a name-brand manufacturer of boswellia serrata.

Zanthin Natural Astaxanthin

This ingredient is a brand-name ingredient like ApresFlex boswellia serrata. It’s produced by Valensa, a lab based in Central Florida that gets its astaxanthin from Chile.

The ingredient is prevalent in ocean animals and plants, says.

As for its clinically-proven effectiveness, Oregon State University’s Linus Pauling Institute, a research department that studies vitamins and supplement ingredients, says that astaxanthin has shown anti-inflammatory capabilities in cells and animals but not in humans.

Regarding humans subjects, anti-inflammatory characteristics were not seen; 4mg of astaxanthin did not affect post exercise muscle injury.

Per HighYa medical adviser Dr. Jason Reed, PharmD, many drugs don’t have the same effects in the human body as they do in individual cells or animals.

Additionally, ConsumerLab says that the daily dosage for astaxanthin should range between 5 and 40 mg per day. The daily MoveMD serving includes 2 mg.

Zanthin” refers to a name-brand manufacturer of astaxanthin.

Type X.I.V. Eggshell Membrane Collagen

Collagen is a basic building block of cartilage. When cartilage in your joints wears down, you’ll start to feel pain because bone is grinding on bone.

The idea behind taking collagen in supplements is that it can help with joint pain because it might encourage cartilage growth or, at least, curbing cartilage loss.

However, an in-depth review of eggshell membrane collagen studies by McGill University’s Office for Science and Society indicates that the existing evidence is underwhelming and that the most promising studies were done on animals, in which supplementation improved some factors related to inflammatory arthritis like cartilage damage and bone resorption.

With regards to human research, a recent randomized trial did demonstrate some promise in those taking eggshell membrane collagen. Significant improvements in measures like stiffness were only found when data was “normalized” – this may cloud the results. Normalization is a process that involves manipulating data in a way to better identify trends by eliminating extreme findings and other “non-normal” distribution.

“These results are all pretty lackluster and point to natural eggshell membrane helping only minimally with pain and stiffness, both in those with and without arthritis,” the McGill concluded.

Type II Chicken Collagen

Chicken collagen is an ingredient we see from time to time in joint health supplements. Companies like MoveMD claim it helps with joint health.

Patients treated with type II collagen had decreased evidence for arthritis at 6-months and 1-year when compared to a group treated with glucosamine. These findings were supported in a rat study a few years later. The addition of 10mg/day of type II to Tylenol treatment for knee arthritis was superior to Tylenol alone – far less than the MoveMD dose.

Hyaluronic Acid

The final ingredient on the list is hyaluronic acid. Because it’s often paired with collagen, you’ll see this ingredient in beauty products (collagen is a skin building-block) and in joint-pain supplements.

ConsumerLab’s research concludes that the existing studies about hyaluronic acid are limited to trials with obese people who have osteoarthritis. Studies analyzing the ingredient’s effects on the average population have yet to be conducted, the site said.

A pilot study concluded that 80mg of hyaluronic acid daily improved quality of life in knee arthritis patients. A study of older patients with osteoarthritis who saw improvement in their arthritis symptoms after taking 200 milligrams of hyaluronic acid each day for a year.

Furthermore, the existing clinical studies of hyaluronic acid required participants to take daily doses of between 80 mg and 200 mg, ConsumerLab said. Your daily dose of MoveMD contains 25 mg.


Type II collagen and Boswellia serrate seem to offer benefit in human subjects, even at doses less than what is included in MoveMD. Hyaluronic acid also has some scientific support, though these studies included daily doses at least 3x greater than what is offered in MoveMD.

Astaxanthin and eggshell membrane cartilage offer less support, particularly in human subjects.

While some of the ingredients included in MoveMD may offer joint pain relief, these were short-term studies. Results are therefore challenging to relate to an issue that often spans decades.

MoveMD Side Effects

The big benefit of this supplement is that our research did not turn up any dangerous side effects. This is commonly an allure of nutraceuticals, though this does not mean that proposed natural ingredients are without risk. Always consult a physician before use.

Boswellia serrate, hyaluronic acid and type II collagen appeara to safe at doses much higher than what is offered in MD, but studies examining daily use were short-term.

More long-term research is needed to identify the full effects of this supplement.

Cost and Return Policy

You have three one-time purchase options and one subscription option to buy this supplement.

One bottle of MoveMD is $54.95 plus $5.95 for shipping. Three bottles will cost you $148.98 and six bottles will cost $268.98. The three- and six-bottle bundles come with free shipping.

There’s a chance 1MD will give you a discount code via a pop-up window, too. The site pitched us a 22% discount and a 10% discount during the time we were on their site. You’ll have to provide your email address to get the discount.

The product was available on Amazon, too, for $60.90 per bottle, which is equal to a single-bottle purchase plus shipping from 1MD’s website.

You have 90 days to return your order if you aren’t happy with MoveMD. You can either return the supplements through the mail or call 1MD.

By mail, you’ll have to write your name, order confirmation number (in the original email confirmation) and “Return” on the outside of the box. You have to include all the bottles you bought in your shipment whether opened or sealed.

The address to which you’ll send the return is: Shipping Dept; 1MD; 675 N. 2800 W #101; Lindon, UT; 84042.

You can also call 1MD at (888)393-4030 between 6 a.m. and 5 p.m. PST, Monday through Friday. They’re available by phone from 7 a.m. to 4 p.m. on Saturday and Sunday, too.

The Bottom Line: Is MoveMD a Good Solution for Joint Pain?

The existing scientific research and expert opinions of the ingredients in this product indicate there’s a good chance MoveMD won’t provide the benefits it claims it can give.

Part of the reason is that there aren’t enough human studies to provide definitive support of the ingredients’ ability to soothe joint pain. Also, the dosages of some ingredients in MoveMD are lower than those used in clinical. More long-term human studies are needed.

Because of this evidence and research, we believe that you most likely will not receive the joint-pain relief you’re hoping to get out of this product.

Also, Reed points out that rheumatoid arthritis can progress if you don’t seek treatment for a doctor, which may happen if you put all your trust in a supplement like this and put off going to your physician.

That being said, we like that 1MD’s customer service line is open seven days a week and that returns are as simple as sending the box back with a note on it. Should you choose to go ahead with your purchase, these will be important benefits.

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