What Is Omegazene?
Formulated by Dr. Sam Walters and manufactured by Lean Lab, Omegazene is a nutritional supplement that promises to deliver DPA, or what he calls the “Missing Omega.”
Just take two easy-to-swallow gel capsules of Omegazene with a glass of water in the morning (this is the 7-second trick frequently referenced by Dr. Walters), and we’re told its scientifically proven formula will be absorbed more efficiently by your body.
As a result, you could experience benefits like healthy blood pressure, increased energy and vitality, reduced risk of heart attack and stroke, an increased craving for healthy foods, and decreased inflammation, which Dr. Walters claims can lead to everything from joint pain and brain fog to Alzheimer’s disease.
Additional claimed benefits for Omegazene include:
- Healthy insulin function, blood sugar levels, and metabolism
- Management of stress-related cortisol and improved mood
- Anti-lipogenic properties that can help your body block fat storage
And because Omegazene’s DPA is derived from wild-caught Menhaden fish in the federally regulated waters of the Chesapeake Bay and the Atlantic Ocean, and then molecularly distilled, the website claims you can expect an ultra-pure formulation that will make fish burps a thing of the past.
Just what is DPA, though, and why does Dr. Walters frequently refer to it as the “Missing Omega”? Will it provide any health benefits? And if so, is Omegazene necessarily the best, most value-laden option for obtaining it?
To help you uncover some answers, let’s start with the first question and work our way from there.
Benefits of Omega-3 and DPA Fatty Acid
According to the Harvard School of Public Health, omega-3 fatty acids are essential for receptor function in cell membranes, for producing hormones that regulate blood clotting, for addressing inflammation, and even for regulating genetic function.
As a result, getting enough omega-3s in your diet (our body is incapable of producing it directly)—whether through a supplement like Omegazene or from foods like fish, nuts, flax seeds, vegetable oils, and leafy vegetables—has “been shown to help prevent heart disease and stroke, may help control lupus, eczema, and rheumatoid arthritis, and may play protective roles in cancer and other conditions.”
Based on what we learned from authoritative websites like WebMD and the Human Metabolome Database (HMDB), the two most important omega-3 fatty acids are:
- Eicosapentaenoic Acid (EPA) – Can prevent blood from clotting and may help reduce pain and swelling.
- Docosahexaenoic Acid (DHA) – May help lower blood triglyceride levels, decrease blood thickness, reduce the risk of heart and circulatory disease, as well as aid in eye and nerve tissue development.
A third, docosapentaenoic acid (DPA), works as an intermediary between EPA and DHA and helps ensure proper cellular membrane development, along with cholesterol transport and oxidation.
As mentioned on the Omegazene website, some research has shown that DPA supplementation can provide a wide range of benefits consistent with other omega-3s, such as brain function and reduced risk of coronary events.
However, after browsing through many of these studies, the clinical evidence appears limited indicating that DPA supplementation can reliably provide meaningfully different—or improved—results over traditional omega-3s like EPA and DHA.
And while we found more than one study investigating the relationship between DPA and lipids and cortisol, we didn’t find any direct indication that this can reduce stress, boost mood, or meaningfully address weight management in humans.
What Ingredients Does Lean Lab Omegazene Contain?
According to the Supplement Facts label listed on the Lean Lab’s website, Omegazene contains the following ingredients:
Fish Oil Menhaden TG Concentrate Omega 3 Fatty Acid 1,000mg
- 20:5 - EPA 300 mg
- 22:6 - DHA 200 mg
- 22:5 - DPA 30 mg
Other ingredients include Menhaden Fish Oil, Natural Antioxidants, Bovine Gelatin, Water, Natural Orange Flavoring, and Glycerin.
WebMD recommends that otherwise healthy individuals take 500 milligrams of EPA plus DHA daily, while those with heart disease or heart failure should take in at least 800 to 1,000 milligrams. Regarding this part, it seems like Omegazene delivers the proper levels for healthy individuals.
However, because DPA-specific research seems to be in its relative infancy, we didn’t find any recommended daily intake (RDI) during our research.
Again, while authoritative websites indicate there’s sufficient clinical evidence showing EPA and DPA can reduce instances of coronary heart disease, decrease cholesterol, reduce the risk of heart attack and stroke, and even treat depression, this same level of evidence doesn't currently seem to support Omegazene’s claimed benefits for DPA.
Are There Any Potential Side Effects With Omegazene?
WebMD indicated that EPA and DHA’s most common side effect is nausea and other types of digestive upset. In rarer instances, they can lead to additional side effects like heartburn, joint, back, and muscle pain; skin rash, nosebleeds, and bruising.
Taking EPA and DHA with meals may help decrease these side effects.
Omegazene also contains fish, which means it’s not suitable for those with fish allergies. This, along with its bovine gelatin, also means that Omegazene isn’t appropriate for vegetarians or vegans.
Finally, the Omegazene website indicates that it shouldn’t “be taken by women who are pregnant or nursing. Additionally, it should not be taken by children or those who are on prescription medications. If you are still unsure if Omegazene is right for you, you should consult with your doctor before using this--or any--product.”
Pro tip: Keep in mind that fish burps are often caused by excess gas, since it can be difficult for the body to digest fish oil—not necessarily from a rancid product. We didn’t encounter any evidence that Omegazene’s formulation would decrease this potential side effect.
Omegazene’s Price & Where to Buy
Omegazene is priced as follows:
- 1 Bottle (60 softgels): $67
- 4 Bottles: $134
- 8 Bottles: $199.60
Note: It looks like Omegazene was previously sold through Amazon, but is no longer available.
Omegazene comes with free shipping within the US, while all orders come with a 60-day money back guarantee. According to the refund details on Lean Labs’ website:
“Only two opened bottles from a multiple bottle order will be accepted for full refund within the 60-day allowance, the rest must be sealed and unopened. If the order is being returned within 30 days of the date of delivery, then only one opened bottle from the same multiple bottle order will be accepted for a full refund."
In order to request a refund, customer support can be reached at 800-545-4130 or email@example.com.
Are There Other DPA Omega-3 Supplements Like Omegazene?
If you search online for terms like “DPA fish oil,” “DPA supplement,” and “Menhaden fish oil,” you’ll find that Omegazene isn’t the only DPA-focused nutritional supplement currently on the market.
This includes other popular options like OmegaActiv Super DPA Fish Oil and JYM Omega-3. How does Omegazene compare?
OmegaActiv Super DPA Fish Oil is priced at $11.99 for 60 softgels and contains 580mg of omega-3 fatty acids: 450mg of DHA, 45mg of EPA, and 85mg of DPA.
On the other hand, Omega JYM will cost you $19.98 for 120 softgels, with 750mg DHA, 750mg EPA, and 150mg of DPA. At $67, Omegazene is more than three times the price of JYM and more than five times as expensive as OmegaActiv.
Which one of these is right for you? Ultimately it comes down to which factors you emphasize.
For example, at $11.99, OmegaActiv is the lowest priced option. Although for $19.98, you’ll get twice as many softgels with JYM, potentially providing a better overall per-capsule value.
OmegaActiv delivers 450mg of DHA (150 more than Omegazene, but 300 less than JYM), and only 45mg of EPA; meaningfully less than either competitor. Also, at 30mg, Omegazene provides the least amount of DPA.
Given these differences, are Omegazene’s customers pleased with their results for the money?
What Do We Know About the Company Behind Omegazene?
While we didn’t encounter any legitimate customer feedback for Omegazene at the time of our research, we did learn that the supplement is manufactured by Lean Laboratories (frequently referred to as Lean Lab) based out of Tampa, FL.
In fact, this is the company for whom Dr. Sam Walters claims to work as Lead Medical Advisor. Dr. Walters also operates Wellspring Clinic based out of Scottsdale, AZ.
Lean Lab wasn’t listed with the Better Business Bureau, and their only other product was Biotic Essentials, a probiotic supplement.
Previously, Dr. Walters earned his Master of Science degree in Biology with an emphasis in Clinical Nutrition, along with a Bachelor’s Degree in Bio-Nutrition. He also holds a Naturopathic Medical Degree. However, it does not appear that he holds a formal medical doctor designation or a board certification in medicine.
Finally, while the website also indicates that “Omegazene is trusted and recommended by elite fitness and health experts, such as NBC’s ‘Most Successful Biggest Loser Ever,’ Pete Thomas,” we didn't find any indication of this during our research.
What’s the Bottom Line About Omegazene Fish Oil?
We didn’t have the opportunity to test Omegazene ourselves, so we can’t provide any firsthand feedback.
Based on what we learned from authoritative websites like WebMD, though, the reported clinical evidence appears to be substantial indicating that EPA and DHA omega-3 fatty acids can provide meaningful health benefits.
However, although it acts as an intermediary between EPA and DHA, these authoritative websites don’t report this same level of evidence supporting DPA’s health benefits—although there is a handful of early positive research.
With this in mind, if you’re willing to roll the dice, we think choosing a DPA supplement could largely come down to overall value. And while there’s currently no recommended daily intake for DPA, if you’re looking for the highest levels per capsule and for the lowest price per dose, it seems like Omegazene falls behind competitors like OmegaActiv Super DPA Fish Oil and JYM Omega-3.