Lectin Shield by Gundry MD Review - Legit or Hype?

By Anthony Dugarte, M.D., C.S.C.S
Updated on: Jan 22, 2020

What is Lectin Shield?

Gundry MD’s claims that their dietary supplement, Lectin Shield, will protect your body from lectin overload.

Lectins are proteins found in both animal and plant products, though they’re most abundant in legumes, fruits, vegetables, and grains. They play a role in many vital biological processes related to cell development and signaling, as well as your immune system.

So why limit their function?

Despite their importance, plant lectins may play a role in the development of conditions like food allergy, inflammatory bowel disease, insulin-dependent diabetes, and rheumatoid arthritis.

There has been discussion regarding meal plans that limit lectin intake, though these diets exclude many common foods and lack strong scientific support. Is there another option for those that wish to avoid the potential harm caused by lectins?

According to Gundry MD, taking two capsules of Lectin Shield twice daily should result in:

  • Reduced appetite and food cravings
  • Increased energy
  • Better digestion and less “Leaky Gut”
  • Cardiovascular support
  • Improved immune system function
  • Reduced Joint Pain
  • Less Brain Fog

They claim that you’ll notice many of these results “within just a few days,” though the most “dramatic” results are likely to become apparent over the course of two to three weeks.

Can one supplement really offer so many benefits?

In this review, we’ll highlight the scientific support for the safety and efficacy of Lectin Shield to help you determine if this is the supplement you’ve been missing.

Who Is Dr. Steven Gundry? Does His Company Make Other Supplements?

Dr. Steven Gundry is a board-certified general surgeon and thoracic cardiovascular surgeon based out of Palm Springs, CA, where he founded The Center for Restorative Medicine Institute.

Here, Dr. Gundry promotes health through diet and lifestyle choices in hopes of helping his patients avoid the surgeries he has performed for over three decades. As he can only see so many patients on a daily basis, he founded Gundry MD to reach as many people as possible.

Dr. Gundry’s focus on diet-based health also lead him to write Dr. Gundry’s Diet Revolution: Turn Off the Genes That Are Killing You and Your Waistline, a three-phase plan that aims to help readers overcome obesity-related diseases.

Gundry MD currently offers over 30 dietary supplements, many of which have been previously reviewed on HighYa.

What Ingredients Are Found in Lectin Shield, and Do They Work?

Lectin Shield’s proposed benefits are thought to be related to its active ingredients. According to the product label, here’s what the supplement contains:

N Acetyl D-Glucosamine (NAG) - 300m

NAG is obtained from shellfish and thought to offer protection from the harmful effects of gluten, though there is minimal support for this, particularly in human subjects.

In a laboratory model, NAG offered protection from the toxic effects of rye, barley, and oat glutens in small intestinal cells obtained from 26 children with gluten intolerance.

Outside of this data, the literature is supporting the use of NAG in this setting is lacking.

Bladderwrack - 200mg

Bladderwrack is a fucose sugar-rich seaweed, also thought to offer protection from gluten.

In a rat study, 575 mg/kg/day of Bladderwrack over 2-weeks was not found to be beneficial as a dietary supplement for weight loss.

Its ability to bind lectins and limit their unwanted effects is unclear.

D-Mannose - 100mg

D-Mannose is a plant sugar that may block lectins, though this benefit has not been demonstrated in substantial scientific investigations with human subjects.

Mannose supplementation in mice on a high-fat diet improved endurance and glucose tolerance, while reducing body weight and body fat.

Okra Fruit - 100mg

Okra is thought to form a gel that can block lectins from attaching to your cells.

In a laboratory study, 0.2 to 2 mg/mL doses of okra extract inhibited the binding of bacteria to stomach cells. Okra may also offer heart health benefits through cholesterol-lowering actions, though this was demonstrated in mice.

Sialic Acid (Mucin) - 100mg

This protein is thought to reduce lectins’ ability to bind to the surface of your digestive tract through its ability to work on cell membranes.

Rats that were injected with 1mg of sialic acid per 50 g body weight for 7-days learned a maze quicker when compared to those treated with glucose.

The brain boosting effects, as well as the other proposed benefits of sialic acid supplementation, have not been demonstrated in human subjects.

Sodium Alginate (Alginic acid) - 100mg

Sodium alginate is thought to bind and remove lectins from your body.

Sodium alginate system formed a gel in the stomachs of rats that served to reduce food intake, body weight and peak blood glucose when compared to control. These findings highlight a potential benefit for supplementation in overweight and obese humans, though research is needed to investigate this possibility.

Vegetable Peptase - 50mg

This enzyme works to break down large protein molecules into smaller ones called peptides.

As this enzyme supports the digestion of the food we consume, supplementation should help avoid symptoms related to undigested food such as bloating, gas, heartburn, and lack of energy.

However, support for the use of vegetable peptidase in this regard is lacking.

Methylsulfonylmethane (MSM) - 50mg

MSM is a naturally occurring sulfur compound thought to offer anti-inflammatory and antioxidant benefits.

Treatment with 3g/day of MSM over 4-weeks in subjects completing resistance training improved blood tests that indicate antioxidant capacity, as well as exercise recovery.

When supplemented along with glucosamine, chondroitin sulfate, guava leaf extract, and vitamin D, 300 mg of MSM improved pain in patients with knee arthritis, though these results were not conclusive.

Larch Arabinogalactan - 50mg

Larch arabinogalactan is a complex carbohydrate from the larch tree (Larix occidentalis) thought to offer anti-microbial and immune boosting benefits.

Those randomized to 4.5g of an larch arabinogalactan had fewer colds over a 3-month span when compared to placebo.

With respect to anti-lectin activity, larch arabinogalactan did not limit lectin activity I a laboratory model.

Is Lectin Shield Safe?

In general, most of Lectin Shield’s ingredients should be well tolerated by most users, with the most common side effects being digestive upset and gassiness/bloating.

These ingredients lack substantial, long-term human studies that investigate various doses in different populations. As most of the available literature is in laboratory or animal models, it is challenging to confidently determine the safety of this product.

Of the ingredients included in Lectin Shield, MSM and larch arabinogalactan have been tested the most in humans. The Food and Drug Administration (FDA) consider MSM to be safe at dosages less than 4845.6 mg/day, while doses up to 4500 mg/day were safe in humans.

Additionally, due to the N Acetyl D-Glucosamine content, you should not take Lectin Shield if you’re allergic to shellfish.

It is safest to speak with your physician before use. Identifying the underlying source for any symptoms you may be experiencing is a good place to start on your road to management.

How Much Does Gundry MD Lectin Shield Cost?

Lectin Shield is available at Gundry MD’s site in the following quantities:

  • 1 Bottle: $49.95 + $4.95 Shipping
  • 3 Bottles: $131.85 + Free Shipping
  • 6 Bottles: $239.70 + Free Shipping

All Gundry MD supplements (more about this next) come with a 90-day money back guarantee, less S&H charges.

In order to request a refund, you’ll need to call Gundry MD customer service at (800) 852-0477.

Lectin Shield is also available through Amazon at $54.25 per bottle. Shipping is currently free, though this supplement is not prime eligible.

Are There Any Alternatives to Lectin Shield?

There are a number of “Lectin Blockers” currently available from different vendors.

Lectin Guard from KaraMD offers a 30-day supply of their formulation for at $29.95 on Amazon. It has bladderwrack, okra fruit, and sodium alginate in common with Lectin Shield, and at comparable doses.

Lectin Lock from Stop Aging Now is yet another option that has an ingredient list almost identical to Lectin Shield, though they offer 400mg of N-Acetyl Glucosamine. They offer multi-bottle savings; 1 bottle/$29.95, 3 bottles/$80.85, and 6 bottles/$149.70.

Another option would be adopting a meal plan that limits lectin intake. Again, it can be challenging to hit daily nutrient requirements by omitting so many foods.

What Are Users Saying About Lectin Shield?

At 4.4 out of 5-stars on over 240 reviews, users seem to report favorable experiences with Lectin Shield.

Over 65% of reviewers rate this supplement at 5-stars. The most satisfied customers cited reduced gas, bloating, diarrhea, and constipation.

Those that rated Lectin Shield 3-stars or less made up about 8% of all reviewers. Unsatisfied customers mainly cited lack of results and expensive pricing for their negative experience, though others mentioned side effects such as diarrhea, constipation, and heartburn.

Gundry MD did seem responsive to those with negative experiences though representatives could do little more than offer a money-back guarantee or suggest seeing a physician.

Will Lectin Shield Provide “Comprehensive Anti-Lectin Health Support”?

Of the many reported benefits from the ingredients included in Lectin Shield, the proposed anti-lectin actions remain unclear. There simply isn’t much support for this action, and most of what the available research is laboratory or animal studies.

This makes determining efficacy challenging as results obtained from animal studies or laboratory models are not necessarily relatable to humans. Promising results in these investigations may highlight the need for more research, however, some of the studies we have reviewed here do not hint at the potential for some of the ingredients.

Also, the doses tested in animals and in the laboratory likely differ from what may be safe and effective in humans. It is therefore hard to draw conclusions from the available research regarding the safety of this supplement.

Though most ingredients are likely safe even at higher doses, be sure to speak to your physician first.

As this is a relatively expensive supplement, particularly if you plan to take it consistently, you may want to look elsewhere in light of the currently available scientific support.


Customer Reviews

Start your review of Lectin Shield:
  • 241 Customer Reviews
  • 90% Recommend This Company
4.4 out of 5
5 star: 65% 4 star: 21% 3 star: 6% 2 star: 2% 1 star: 4%

 Our Promise to You

To safeguard you and ensure helpfulness and relevance, our compliance team manually assess every customer review before it goes live.

We have a zero-tolerance policy for fake reviews, and companies cannot control or alter any reviews at any time.

Sort reviews by:

  • This company is actively collecting reviews from its customers. All reviews submitted are subject to moderation and approval to ensure they meet our Review Guidelines.
  • In a pinch

    • By Dale Salomon,
    • Tampa, Florida,
    • Jun 15, 2017
    • Verified Reviewer
    Overall Experience:

    I have been following this diet since January of 2017. I underwent open heart surgery to replace my bicuspid aortic valve, which had become stenotic and calcified.

    I began plant paradox with the hope that I could help my cow valve last as long as possible. I have lost 28 lbs and have been able to stop statins and beta blockers.

    I am pretty faithful at following the rules. But in a pinch, I use the Lectin Shield. For example, if you are out to dinner and can't be sure what your food ate, take the Lectin Shield. Or if you just can't say no to the pizza, take the Lectin Shield.

    Thank you Dr Gundry.

    Sincerely,

    Dr. Dale Salomon

    Bottom Line: Yes, I would recommend this to a friend


  • I love Lectin Shield

    Overall Experience:

    From the first time I took Lectin Shield, I noticed a definitely change in my digestion.

    One of the first things that happened is that it seems to have helped with my gastroesophageal reflux. It just has made me feel much better overall after eating. When I take Lectin Shield with my meals, I sleep much better and there is less a chance of having an episode with the dreadful GERD.

    Bottom Line: Yes, I would recommend this to a friend


  • A life changer

    Overall Experience:

    Dr. Gundry's products have changed my life. My Primary Care Doctor was astonished by the significant changes in my bloodwork. I took the book with me, and I am certain my doctor will be ordering his own copy and following my progress, curiously. I feel better than I have since childhood and I am actually healing. Dr. Gundry is a blessing in my life.

    Bottom Line: Yes, I would recommend this to a friend


  • Lectin Shield

    • By Terri McFaul,
    • Fort Worth, Texas,
    • Jun 20, 2017
    • Verified Reviewer
    Overall Experience:

    I have just started using the product. I use it when I'm in a situation I eat food with lectins. I usually try to stay away from foods with lectins. I read The Plant Paradox (more than once) and am learning more about lectins and foods with lectins. My goal is to keep lectins out of my diet now that I've learned more about the gut issues they cause. I have experienced some of the discomforts mentioned by eating foods with lectins. I use to eat many of those foods.

    Bottom Line: Yes, I would recommend this to a friend


  • Excellent

    Overall Experience:

    As I move toward changing my (our, hubby too) diet, as humans, it isn't always perfect. Lectin Shield gives me the peace of mind that I am moving forward and making progress. My digestion is 100% better (no gas). AND, if you have not read the Plant Paradox yet, don't waste another minute allowing our American culture to poison you. Folks, this is REAL!

    Bottom Line: Yes, I would recommend this to a friend


  • Love!

    • By Kirsten Zerr,
    • Grinnell, KS,
    • Jun 21, 2017
    • Verified Reviewer
    Overall Experience:

    It's hard for me to completely give up all lectins, especially when out with friends or family, so it's great to have a backup that you know will still be protecting your gut. This, along with Gundry's diet, has really helped me to reach peak health and fitness!

    Bottom Line: Yes, I would recommend this to a friend


  • Lectin Shield, a Godsend

    • By Myrn Corban,
    • Portland, OR,
    • Jun 21, 2017
    • Verified Reviewer
    Overall Experience:

    My adult son was suffering terribly with skin rashes, which the doctors were at a loss to treat except with strong medications with unpleasant side effects. Then we read about Lectin Shield and decided to give it a try. His skin rashes totally cleared up and his spring allergies are dramatically improved.

    Thank you, Dr. Gundry, for your research, which has restored health unto our son. We are just so thankful for Lectin Shield. We never expected to get these amazing results!

    Bottom Line: Yes, I would recommend this to a friend


  • Lectin blocker works

    • By Marci Kelley,
    • Newport, OR,
    • Jun 22, 2017
    • Verified Reviewer
    Overall Experience:

    With years of experience using natural health care supplements, I can unequivocally recommend Dr. Gundry's Lectin Shield as one of the few products that works the first time, and every time, to do what it claims. It blocks lectins.

    After reading Dr. Gundry's newest book, The Plant Paradox, my husband and I immediately recognized the importance of avoiding lectins. We ordered Lectin Shield right away. The first test was using it at the beginning of meals when we're eating in restaurants during our date nights. What a difference.

    Even with his almost always "good" food choices, before Lectin Shield, my husband would notice congestion and other digestive problems. With my more frequent "far less than good selections," I could always tell there was something I probably should not have chosen.

    Not anymore. Now we both enjoy our nights out with far fewer, if any, negative effects. As we learned in The Plant Paradox, even if your body is ignoring the effects of lectins, you need to avoid them as much as possible. Lectin Shield definitely helps. The more often you use it, the more you and your body will want to thank Dr. Gundry.

    Bottom Line: Yes, I would recommend this to a friend


  • Blocking lectins

    • By Fay Krapf,
    • North Carolina,
    • Jun 25, 2017
    • Verified Reviewer
    Overall Experience:

    I love the idea of being able to block some of those lectins in food, especially when I am eating out. Great idea to make a product that uses natural foods like okra to block those lectins. I had two of them tonight before a meal with green and yellow peppers and tomatoes. Thanks!

    Bottom Line: Yes, I would recommend this to a friend


  • Grateful!

    • By Mike Celmer,
    • JohnsBurg, IL,
    • Jun 26, 2017
    • Verified Reviewer
    Overall Experience:

    I am looking forward to seeing the long-term benefits from Lectin Shield. I just started and have noticed a difference in my "morning routine" and am hoping for the best. So far so good, I am pleased.

    Bottom Line: Yes, I would recommend this to a friend


  • Peace of mind when eating a dish with approved ingredients but you are not the cook

    Overall Experience:

    Infrequently is when we eat out or at someone else's home. Though approved foods for the Gundry diet are used, we are not the chef in the kitchen, and are aware there may be ingredients we are not aware of. It gives us a peace of mind at home, as well as when eating out. Far fewer tummy aches. Thank you so much for this product.

    Bottom Line: Yes, I would recommend this to a friend


Showing 1-11 of 241

Write a Review for Lectin Shield!

Share your experience to help others discover great products!

Write a Review
Lectin Shield