Lipozene Review: Effectiveness, Clinical Research, Side Effects, Cost

By HighYa Research Team
Updated on: Dec 18, 2019

Medically Reviewed by Anthony Dugarte, M.D., C.S.C.S

What Is Lipozene?

Lipozene is an As Seen On TV weight-loss supplement that utilizes a special type of fiber which it claims can make you feel full faster, eat less and, therefore, lose weight.

The fiber, called “konjac root”, has been used as a weight-loss aid in Japan for centuries, the site states, and is “one of the most studied ingredients for weight loss.”

In this review, we’ll talk about how to take Lipozene and how it works, side effects, what it costs, and how it compares to similar supplements.

How to Take Lipozene and How Its Ingredients Work

The dosage guidelines for Lipozene are simple. You take two capsules with at least 8 ounces of liquid around 30 minutes before each meal up to three times a day. This two-pill dose contains 1.5 grams of konjac root. Taking Lipozene three times a day means you take in 4.5 grams of konjac root.

This half-hour cushion allows the konjac root’s main component, a fiber called “glucomannan,” to start working. Its mechanism of action regarding weight loss is thought to be related to an ability to absorb water and expand – limiting space for additional food and creating a feeling of fullness.

Since you’ll start eating less, in theory, you’ll reduce your calorie intake and start losing weight. On top of that, Lipozene has an app that will track your progress and remind you to take your capsules.

While it is well known that lower body weight is associated with fiber intake, type or dose of fiber did not seem to affect the sensation of fullness or food intake. A 2005 review specifically examining glucomannan found doses at 2-4g/day resulted in significant weight loss in overweight and obese subjects.

In a randomized trial, glucomannan added to a calorie restricted diet reduced body weight in both healthy and obese subjects, though increasing the dose from 420 mg to 4320 mg did not offer an added benefit. In a 2008 review, glucomannan resulted in an average weight loss of about 1% body weight over 5 weeks – concluding that its weight loss effects were mild.

In a 2013 randomized trial, overweight and obese patients taking 1.3g of glucomannan did not experience a significant reduction in weight when compared to placebo. A 2015 review concluded that glucomannan may reduce weight in adults in the short-term, but evidence for use in children is lacking.

In addition to weight loss claims, Lipozene also states that you can lose weight without changing your lifestyle and that 78% of weight lost is pure body fat. We have found noncredible studies that corroborate these statements.

In fact, glucomannan was proven effective when added to a calorie restricted diet, and proven ineffective when participants were on self-directed diets. Additionally, as many of the studies have found significant, but mild, reductions in weight with glucomannan, it is unlikely that this supplement alone will result in meaningful weight loss in the absence of diet and exercise.

Lastly, as most studies followed patients only for a few weeks, we do not know the lasting effects of weight loss associated with glucomannan. As lifestyle changes are vital for maintenance once you reach your target goal, it is unlikely that this supplement has long-term value alone.

Safety and Side Effects

Dosages of glucomannan similar or beyond that which is included in Lipozene are generally safe and well tolerated.

Belching, bloating, and stomach fullness occurred more frequently in glucomannan when compared to placebo, though these effects were mild and self-limited. Liver and kidney labs remained unaffected.

“The FDA warns that products containing glucomannan may pose a choking hazard (or cause intestinal blockage) if not taken with enough water to keep it moving along,” they noted.

Though generally safe, always consult a physician prior to starting a new supplement.

Lipozene Pricing and Return Policy

For $29.95, you can purchase two bottles of Lipozene and get a bonus bottle of ORI’s MetaboUp PLUS, a supplement that supposedly boosts your metabolism and energy. Since each bottle of Lipozene contains 60 capsules, two bottles will last you 20 days.

Shipping is free but there is a non-refundable $1.35 processing fee.

The supplement comes with what ORI calls a “30-day money-back guarantee.” If you aren’t happy with how the supplement works, you can send it back to them provided you contact customer services at (888)220-8907 and get a return authorization number.

You’ll need to write this number on the box in which you ship the product back to ORI. Refunds will be for the original amount minus the $1.35 processing fee. Also, the return policy applies only to TV and internet purchases.

Autoship Warning

Lipozene’s fine print uses “subscription” language, which typically means that Lipozene will sign you up for recurring shipments (and charges) when you make your first purchase. We called them to clarify this.

The phone representative told us that ORI will send you a new shipment of Lipozene at the same price point and will continue to do so until you call them to cancel.

So, while they say their 30-day guarantee is your window for returning the product if you aren’t satisfied, it’s really the time you have to call in and cancel your “membership” to their Lipozene auto-shipments.

If you want to learn more, watch our video about similar auto-ship programs.

Pro tip: You’ll have to wait several minutes to connect with a customer service representative. When their automated phone service asks you to provide your payment information, don’t do anything. Wait until you’re connected with a real person.

Comparing Lipozene to Two Popular Konjac Root Supplements

To give you an idea of how much or how little of a bargain you’re getting with Lipozene, we went to Amazon and took a look at the top-rated konjac root supplements.

Here’s a comparison chart:

Lipozene Pure Naturals Konjac Root Nova Nutritions Konjac Root
Price $14.97 $17.99 $10.49
Daily dose of konjac root 4.5 grams 6 grams 6 grams
Number of servings per bottle 30 180 180
How long one bottle will last 10 days 60 days 60 days
Average Amazon rating 3.2 stars, 415 reviews 3.6 stars, 125 reviews 3.7 stars, 252 reviews

Based on our research, we found that the two competing capsules on Amazon seem to include the same ingredients, are made in the United States and have better customer reviews and pricing than Lipozene.

Price is an important factor in making a purchase, so here’s how much each supplement will cost over the course of 12 weeks, per each bottle’s dosage recommendations:

  • Lipozene: $149.75
  • Pure Naturals: $35.98
  • Nova Nutritions: $20.98

Considering that Nova Nutritions’ supplement gets better reviews than Pure Naturals and Lipozene and is cheaper, we think the data shows there’s a good chance you’ll be most satisfied with their product when compared to the other two.

Other Concerns

The company behind Lipozene is Obesity Research Institute LLC (ORI). Our research turned up the fact that ORI is located in Carlsbad, CA. In 2005, an investigative branch of the Better Business Bureau reprimanded ORI for claiming Lipozene helped millions of people and more than 20 million bottles sold.

At the time of publishing, Lipozene claimed that they’d sold more than 25 million bottles on one page and on another page claimed more than 30 million. We could not verify this fact.

The Final Word: Our Thoughts About the Pros and Cons of Lipozene

Fiber intake seems to be associated with lower body weight. Lipozene offers glucomannan, a fiber supplement that has been associated with weight loss in both healthy and overweight individuals.

Available research shows that, although significant, weight loss with glucomannan is mildly effective in the short-term with a calorie restricted diet. It does not seem to be effective in those that follow self-directed diets. This information seems to counteract Lipozene’s claim that you do not need to implement a lifestyle change.

Beware of products with marketing that suggests this. There is no magic bullet. Weight loss supplements or medications should always be part of a more comprehensive plan that includes diet and exercise, as well as the opinion of a medical professional.

If you want an alternative method for taking supplements, read through our guide to losing weight through changing your habits. In it, we talk about our research on weight loss supplements and why changing certain habits can help you effectively lose weight.

Read 19 Lipozene Customer Reviews and Complaints

Write a Review
Average Customer Rating: 1.8
Rating Snapshot:
5 star: 3 4 star: 0 3 star: 1 2 star: 2 1 star:  13
Bottom Line: 21% would recommend it to a friend
Showing 1-11 of 19
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  • Wonderful so far

    • By Julie,
    • Indiana,
    • Jun 24, 2015

    I just started taking it for 3 days actually. I'm not hungry. I feel full all day. Haven't snacked at all. Loving it so far.

    Bottom Line: Yes, I would recommend this to a friend

  • Lipozene works

    • By Monica,
    • Moscow, TX,
    • Jun 24, 2015

    Lipozene really does work but you have to cut back on food. Eat healthier choices and do some exercises. I'm using it and love the results.

    Bottom Line: Yes, I would recommend this to a friend

  • Worked great for me!

    • By Amy R.,
    • Tennessee,
    • Feb 10, 2019
    • Verified Reviewer

    So, I read a lot of reviews that were negative, but mine is a POSITIVE ONE! I started taking Lipozene in the early part of the summer of last year, 2018. Let me just say when I started on my weight loss journey I weighed 660lbs. When I started on Lipozene I weighed 550lbs and now I weigh 390lbs, so I've lost a total of 160lbs with the Lipozene since the beginning of the summer of 2018. So, I've had great results with mine. I hope more people have good luck with theirs. In total, I've lost 270lbs and I weigh 390lbs now and still going to my goal. I've gotten a lot healthier and feel a lot better, so THANK YOU LIPOZENE! I get mine from Walmart each time I get mine.

    Bottom Line: Yes, I would recommend this to a friend

  • Lipozene

    • By Faye H.,
    • Los Angeles, CA,
    • Apr 7, 2019
    • Verified Reviewer

    On on March 26, 2019 at 11 am I placed my order with a customer service representative for Lipozene. On April 2, 2019 I received my order in the mail, 7 days I received 1 120-count bottle of Lipozene that is to help reduce weight and help reduce body fat, and 1 bottled of MetaboUP Plus that increases energy and helps increase metabolism.

    So this morning I took two Lipozene with 12oz of water with two MetaboUP Plus, let’s see how it’s going to work for me. The reviews are across the board. Some say it works, but there are just as many people that say the product doesn’t work. So it’s day one on Lipozene, I’ll repost in a week. I’m looking to lose 30 pounds before July 3, 2019 for my 23rd wedding anniversary, wish me good luck.

    Bottom Line: Yes, I would recommend this to a friend

  • Does work but...

    • By Marie Weisensee,
    • Wichita, KS,
    • Oct 18, 2014

    This product worked great for me. I took it for about 3 months and lost 17 pounds. The only problem I started experiencing is hair loss. So I had to quit and was afraid I was going to go bald. OMG! It was great but I don't want to be skinny and then be bald and then have to find something to grow my hair back.

    Bottom Line: No, I would not recommend this to a friend

  • Lipozene pills

    • By Betty W.,
    • Florida,
    • Jun 20, 2018
    • Verified Reviewer

    I bought a couple of bottles up the local Walmart in Arcadia, Florida and took some and it never helped me to lose the weight. Plus it gave sugar problems because it made my sugar go up, so I would love to have a full refund of my money.

    Bottom Line: No, I would not recommend this to a friend


    • By Lindy Blackburn,
    • FT. WORTH TX.,
    • May 28, 2014

    Do not waste your money! I only gave it one star, because there was no other way to review it. Not because it deserved it.

    Bottom Line: No, I would not recommend this to a friend

  • No, No and No

    • By Brandy,
    • Texas,
    • Aug 8, 2015

    I have been taking this for two months and nothing. I stopped taking then because they made me feel yucky. Now I just eat healthy, do yoga, and run two miles daily and I'm down 5 lbs in a week.

    Bottom Line: No, I would not recommend this to a friend

  • I have taken 3 bottles of Lipozene, it does not work. I am very unhappy with it.

    • By Brenda Campbell,
    • Collinsville IL,
    • Oct 7, 2015

    Review is it does not work. So do not waste your money.

    Bottom Line: No, I would not recommend this to a friend

  • Lipozene does NOT work.

    • By Sharon,
    • Dayton OH,
    • Mar 4, 2016

    4 weeks on Lipozene and I've only lost half a pound and I've been dieting. Eating healthy and following package directions and nothing. The only benefit is that they keep me regular.

    Bottom Line: No, I would not recommend this to a friend

  • Garbage, buy a laxative instead!

    • By Rich,
    • Beecher, IL,
    • Mar 6, 2016
    • Verified Reviewer

    People years ago used laxatives to lose weight. This pill is no different except that it has extra vitamins in it. It does not curb your appetite, boost your energy level or magically burn belly fat. I work out at the gym 4 or 5 daya a week. This is not the solution. Glad I bought the buy one get one free deal at Walmart (bought 4 total) so I didn't get suckered into any automated billing system. A waste of 40 bucks but there are better energy supplements out there. Live and learn people and don't fall for the hype.

    Bottom Line: No, I would not recommend this to a friend

Showing 1-11 of 19

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