GutConnect 365 Reviews - Does It Work, Safety, Ingredients

By HighYa Editorial Team
Updated on: Oct 16, 2019

Medically Reviewed by Jason Reed, Pharm.D.

GutConnect 365 is a powdered supplement that claims to cure a condition known as “leaky gut” through a proprietary formula of nine different superfoods.

Made by United Naturals, the supplement claims it can boost your energy levels, health and wellness by stopping leaky gut.

This GutConnect 365 review addresses the ingredients, safety profile, and whether the supplement is effective for you.

Directions for Use

This supplement comes in jars containing about a half-pound of supplement that includes nine different main ingredients along with a Stevia leaf extract for sweetening. GutConnect 365 comes in vanilla cinnamon flavor.

Take the supplement once a day; time of day doesn’t matter. For the first two weeks you’ll want to take half a scoop at a time and then, after two weeks, switch to one full scoop per day.

Pour the powder into a glass of water and mix using the scoop that the supplement comes with.

Your first container should last you around 37 days with subsequent containers lasting 30 days.

What Is Leaky Gut and Is It Real?

Nailing down a definition for leaky gut is tough because there are various schools of thought as to whether it even exists and what it is, exactly.

In a basic sense, your intestines have a barrier between them and your bloodstream. The intestinal lining is not 100% foolproof, so extremely small particles will make their way out of your intestines and into your bloodstream.

Certain circles say this less-than-perfect barrier is the cause of all kinds of sicknesses.

However, many in the medical community aren’t convinced leaky gut is a real condition on its own and is most often a symptom of an intestinal disorder or disease.

For example, non-profit research group the Canadian Society of Intestinal Research’s (CISR) page on “leaky gut syndrome” indicates that many alternative medicine doctors say leaky gut exists, while, “most physicians maintain that there is not enough research to prove that it is a legitimate issue.”

The CSIR goes on to say, however, that some individuals have a condition in which substances from the intestines can cross over into the bloodstream.

“Physicians sometimes find increased intestinal permeability in those who have Crohn’s disease, celiac disease, in individuals receiving chemotherapy, and those who have a high intake of bowel-damaging substances such as aspirin and alcohol,” they note.

The key to understanding these trends, the CSIR points out, is that leaky gut is a symptom of these various conditions and not a cause.

“Furthermore, research shows that increased intestinal permeability sometimes has beneficial effects, such as improving water and nutrient absorption as well as activating the immune system,” they said.

Others don’t take quite as hard a stance against leaky gut syndrome. For example, Dr. Marcelo Campos wrote an article for the Harvard Health Blog in which he has a more favorable view on the legitimacy of leaky gut.

“Controversy still exists on whether leaky gut causes the development of diseases outside the gastrointestinal tract in humans. However, it is always a good idea to eat a nutritious, unprocessed diet that includes foods that help quell inflammation, which may, at least in theory, help to rebuild the gut lining and bring more balance to the gut flora,” he wrote.

However, there is some evidence that stomach inflammation can cause the intestinal wall to become more permeable, according to pharmacist Dr. Jason Reed. This shouldn’t be confused with the leaky gut syndrome United Naturals talks about, though.

Ingredients

United Naturals provides a list of this supplement’s ingredients. We have included that list below:

  • L-Glutamine (5000 mg)
  • Quercetin dihydrate (500 mg)
  • Slippery elm bark (150 mg)
  • Organic marshmallow root (150 mg)
  • N-acetyl glucosamine (150 mg)
  • Licorice root extract (150 mg)
  • Aloe vera extract (50 mg)
  • Maitake mushroom extract (30 mg)
  • Zinc orotate (20 mg)

One ingredient that has a legitimate chance of helping you is L-glutamine. This ingredient is also known as “glutamine.”

It provides fuel for the cells that line your stomach, according to consumer research site ConsumerLab.com. The typical therapeutic dosage amount is 3 to 30 grams per day, separated into several doses.

There may be some evidence that glutamine can help decrease the permeability of your intestines. ConsumerLab points to a study in which two sets of patients underwent abdominal surgery. One group took a glutamine serum (liquid) while the other group took a placebo (no drugs).

“Glutamine can decrease intestinal permeability, maintain intestinal barrier and attenuate systemic inflammatory response in early postoperative patients,” the researchers concluded.

This study is an important one because it was double-blind, randomized and placebo-controlled, which is the gold standard of research. The drawback here is that, even though the study was done with the right methodology, it’s saying glutamine worked for post-op patients.

Therefore, it’s not a guarantee it will have the same effect on someone who didn’t have surgery and is looking for a way to improve their intestinal health.

ConsumerLab makes no mention of quercetin being used for leaky gut. The most common uses for it include allergies and prostatitis.

Calloway Cook, the founder of supplement company Illuminate Labs Inc., told us that the rest of the ingredients in the list above have “no strong evidence for their efficacy in treating leaky gut.”

Based on the information we found in medical literature, the ingredients included in GutConnect 365 have little evidence linking them to being effective to cure leaky gut.

Side Effects

L-glutamine included in this supplement could pose a threat to those who have epilepsy and take glutamate-blocking drugs.

Also, the site noted that those who are sensitive to monosodium glutamate should avoid glutamine, too, because the body breaks down glutamine into glutamate.

Pricing and Return Policy

According to the company website, the following purchase options are available:

  • 1 Jar: $54
  • 3 Jars: $134
  • 6 Jars: $244

All products come with free shipping.

You have 60 days from the date of purchase to do so for a full refund less shipping & handling.

United Naturals allows you to return up to two empty or partially used containers of GutConnect 365 and get the full refund price. However, if you return more than two containers, they will prorate the refund amount of any additional containers beyond two.

The Bottom Line

There are two main factors at play with this supplement.

First, it makes a specific claim to alleviate leaky gut, a condition about which there’s some debate. For the most part, doctors agree that leaky gut is a real symptom associated with various bowel conditions and diseases like Crohn’s Disease.

However, we didn’t find nearly as much evidence for leaky gut existing in average people without any intestinal issues, auto-immune diseases or inflammation.

Now, assuming that you are dealing with leaky gut issues related to an intestinal issue, it’s important to know if GutConnect 365’s ingredients can help.

Based on medical reviews, strong support for the ingredients in this supplement that can stop leaky gut is lacking.

L-glutamine has the most promise but, as we pointed out earlier, the legitimate study we found indicates glutamine was helpful for post-operative patients who underwent abdominal procedures.

Also, the study noted the glutamine the subjects took was in liquid, not the water-soluble form GutConnect 365 comes in.

Using GutConnect 365 on a regular basis would mean you’ll spend around $648 per year. Without strong clinical support that this product may address your intestinal issues, this is a considerable amount of money to spend.


Customer Reviews

Start your review of GutConnect 365:
  • 240 Customer Reviews
  • 95% Recommend This Product
4.7 out of 5
5 star: 79% 4 star: 12% 3 star: 4% 2 star: 1% 1 star: 2%

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  • Feeling the healing

    • By Kathy M.,
    • Merrill, WI,
    • Sep 30, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    I have been eating poorly for years. Now at 57, my body is talking back.

    I am a believer of a holistic approach to health. When I ran across GutConnect, I was elated. After trying it for 60 days I am sold. It tastes delicious with my morning coffee. It has also helped with my digestion and no more bloating. I am excited to see the long term results.

    Pros and Cons:

    • Taste
    • Ease of use
    • Cost
    • No “cons” were specified in this review

    Bottom Line: Yes, I would recommend this to a friend


  • GutConnect 365 really works

    • By Pasquale M.,
    • Pierrefonds, Quebec, Canada,
    • Sep 30, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    I've been using it for over a month now and my stomach has never felt better. It's so simple to use. Just one scoop full in the liquid of your choice. I use warm almond milk and sometimes just hot water.

    Pros and Cons:

    • Very effective
    • Great taste
    • Easy to use
    • It's rather expensive

    Bottom Line: Yes, I would recommend this to a friend


  • Helps my weight and overall feel

    • By Mark C.,
    • Lineville, NC,
    • Sep 30, 2020
    • Verified Reviewer
    • Length of Use: 3–6 months
    Overall Experience:

    Pleasant taste, helps curb my appetite and I feel better. Easy to drink, helps regularity and overall wellbeing. Nice drink in the morning. The cinnamon taste makes it more inviting.

    Pros and Cons:

    • It works
    • Pleasant taste
    • Helps regularity
    • Viscosity
    • Bit messy to mix

    Bottom Line: Yes, I would recommend this to a friend


  • Amazing!

    • By Afifa S.,
    • Montréal, Québec, Canada,
    • Sep 30, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    Since I've started using GutConnect 365 I feel so much better. I can eat and digest food! I used to suffer from cramps and my tummy was always bloated. After about 1 week of using GutConnect 365 I started seeing a difference...my tummy was flat and less cramping. As the weeks passed, it got better and better. And because I could actually digest properly I felt so much better and my energy level went up. And it tastes delicious. I'm so happy and grateful for this product.

    Pros and Cons:

    • Better digestion of food
    • Less bloated
    • Flatter stomach
    • More energy
    • Because I live in Canada, with the exchange rate it's a little expensive

    Bottom Line: Yes, I would recommend this to a friend


  • Awesome benefits

    • By Rogelio F.,
    • San Diego, CA,
    • Sep 30, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    Since I started using GutConnect I’ve been feeling so much better without stomach pains and cramping, I drink it every morning and feel great all day.

    Pros and Cons:

    • Benefits
    • Easy to use
    • Flavor
    • No “cons” were specified in this review

    Bottom Line: Yes, I would recommend this to a friend


  • Excellent product!

    • By Erin C.,
    • Minneapolis, MN,
    • Sep 29, 2020
    • Verified Reviewer
    • Length of Use: 3–6 months
    Overall Experience:

    I was skeptical about how effective this product would be, but turns out I didn't need to be. It worked almost immediately for me, and I couldn't be happier with it. The taste is awesome, too!

    Pros and Cons:

    • Effectiveness
    • Taste
    • Simplicity
    • Cost
    • Not able to order easily online
    • Trouble with trying to get the referral discount; had to contact customer service multiple times to help resolve

    Bottom Line: Yes, I would recommend this to a friend


  • I believe in it

    • By Fileza H.,
    • Fort Hood, TX,
    • Sep 29, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    The flavor, taste, and smell are way better than I thought it would be. After Dr. Pedre advised putting it in my coffee (I use almond liquid creamer) I mix a scoop in my creamer and place it on my Keurig mixer to whip it and I haven't looked back. Now I'm officially hooked. I add a teaspoon of MCT oil and coconut oil and I'm officially regular. Still bloated but I'm regular. I haven't been regular in years. I def approve of this product.

    Pros and Cons:

    • The smell
    • The taste
    • How easily it dissolves
    • Not sure how well it's working in my system

    Bottom Line: Yes, I would recommend this to a friend


  • Gut feeling better after 10 days

    • By Talyn N.,
    • Federal Way, WA,
    • Sep 29, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    I started GutConnect 365 in hopes I might have less bloating, less days with stomach pain, and upset stomach. Before it was about 3-4 times a week that I had discomfort or felt like I don't want to leave the house. I could feel something going on in my lower abdomen about 5 days after taking GutConnect. It was just noticeable enough like something is working there but not uncomfortable. By day 10 I already could tell I only had 1 day of discomfort. By day 30 I think I had about 3 days the whole month that I had discomfort. The flavor is pretty okay. Not great, I definitely don't crave it, and I kind of make a face after gulping it down, but not so bad that I can't take it. I'm really happy with the results and am definitely excited about my next jar coming in!

    Pros and Cons:

    • Easy to take
    • Feel better fast
    • Flavor is not the best

    Bottom Line: Yes, I would recommend this to a friend


  • I have tried many products but this one works!

    • By Leslie N.,
    • Carville, LA,
    • Sep 29, 2020
    • Verified Reviewer
    • Length of Use: Less than 3 months
    Overall Experience:

    There were some foods that my stomach would not consume and all that has changed. I had the worst monthly periods, but not anymore. I was constantly bloated, but not anymore. GutConnect 365 is the greatest product that I have ever used! I am healthier, more energized, and no longer bloated. I was sluggish all the time. But now, I have more energy than ever each and every day. I feel like a new person.

    Pros and Cons:

    • It works better than described
    • Dr. Pedre knows what he’s doing
    • It gives me energy
    • No “cons” were specified in this review

    Bottom Line: Yes, I would recommend this to a friend


  • It works

    • By Mora G.,
    • Bradenton, FL,
    • Sep 28, 2020
    • Verified Reviewer
    • Length of Use: 3–6 months
    Overall Experience:

    It was amazing. I had been struggling with bloating in my abdomen. I had tried every probiotic, I had tried changing my diet, and it wasn't until I started using this product that within a month I noticed my belly was flattered, I didn't have as much gas, and I was able to fit into my clothes. And I didn't look perpetually pregnant. So I want to thank you very much and tell you I will continue to use this product.

    Pros and Cons:

    • Easy
    • Tastes good
    • Works
    • Price

    Bottom Line: Yes, I would recommend this to a friend


  • Gut relief

    • By Monica T.,
    • Tacoma, WA,
    • Sep 28, 2020
    • Verified Reviewer
    • Length of Use: 3–6 months
    Overall Experience:

    I am at the end of my 3rd container. My stomach issues have really calmed down. I am rarely constipated and my body now discharges body food waste on a regular, daily schedule. I generally feel all-around better.

    Pros and Cons:

    • The taste is really good
    • It is convenient and easy to include in my daily routine
    • It truly seems to really work
    • United Naturals has not been sending me any discount coupons

    Bottom Line: Yes, I would recommend this to a friend


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