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New U Life claims that SOMADERM Gel will provide all the benefits of growth hormone when applied transdermally. However, the ingredients lack strong scientific research.

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SOMADERM Gel Review: Does It Provide Benefits?

By Anthony Dugarte, M.D., C.S.C.S

Updated on: Apr 23, 2020

What is SOMADERM Gel?

SOMADERM Gel is a synthetic version of growth hormone (GH) that allegedly improves bone and joint health, build muscle, reduce fat, and improve sleep with regular use.

Your pituitary gland produces GH, a hormone with wide-ranging effects related to growth, development, metabolism, and physical performance.

Deficiency can occur spontaneously, and without a clear cause, it may be associated with an underlying medical condition. As GH has so many important actions, the unwanted effects of associated with low levels are numerous and can include:

  • Mental decline
  • Depression and anxiety
  • Fatigue
  • Decreased muscle mass and strength
  • Fat accumulation around your midsection
  • Decreased bone density
  • Poor heart function and increased plaque
  • Blood clotting

There are medical treatment options for those with GH deficiency, but New U Life claims to offer a non-prescription option that can provide some of the benefits of GH.

New U Life states that you can preserve your youth and fight aging by using SOMADERM Gel regularly.

But is there any merit to these claims?

In this review, we'll help you answer this question by highlighting the available support for SOMADERM Gel's active ingredients.

But first, let's discuss the recommended use for this supplement.

How to use SOMADERM Gel

According to the website, you should apply 2-4 pumps in the morning and 2-4 pumps in the evening for 5-days on. You would then take a 2-day break.

Also, New U Life recommends applying SOMADERM Gel to your armpits, forearms, wrists, and behind the knees. Rotate these areas of the application so no patch of skin is overused.

As SOMADERM Gel is transdermal and absorbed into your blood circulation through the skin, you must apply it over thin areas of your skin. The concentration of the supplement can be drastically reduced if you massage it into thicker areas of skin like your thigh or calf, for example.

While New U Life claims that following these steps will allow for SOMADERM Gel to be readily absorbed into your bloodstream, they do not detail how quickly you can expect to see results.

The Research Behind SOMADERM Gel's Active Ingredients

New U Life claims that SOMADERM Gel's proposed benefits are made possible by blending just 3 ingredients.

The SOMADERM Gel active ingredients are:

  • Somatropin 30X
  • Glandula Suprarenalis Suis 6X
  • Thyroidinum 8X

The dosing of the SOMADERM Gel ingredients is listed as the number of times that they've been diluted. The larger numbers represent weaker concentrations for that particular ingredient.


According to New U Life, the star ingredient, somatropin, is a synthetic GH that is available for over-the-counter (OTC) use because it has been diluted 30 times.

Somatropin allegedly offers many of the benefits of GH while avoiding the unwanted side effects that may be associated with injectable forms of treatment.

GH gel formulations were tested in the late 70s and compared to standard injectable treatment in children with GH deficiency. While the gel was effective in stimulating growth and preventing the larger spikes in GH levels associated with injections, neither the gel nor the injections were able to sustain the growth rate of these children.

In an animal study, the concentrations achieved with transdermal GH preparations were comparable to injectable forms. Rather than massaging a gel into the skin, a radio-frequency device was used to create pores, however.

In the long-term, somatropin treatment in those with GH deficiency can improve body composition, muscle strength, bone density, and cholesterol levels.

However, the support for treatment with diluted, transdermal formulations of somatropin is lacking.

Glandula Suprarenalis Suis

Your adrenal glands play a wide array of roles vital to normal body functions. They help regulate metabolism, blood pressure, fluid balance, and blood sugar.

According to New U Life, glandula suprarenalis is an extract intended to support the function of your adrenal glands.

We were unable to track down any credible research regarding this ingredient, however. Thus, there is currently no support for its efficacy or safety.


Your thyroid gland is part of a system that helps regulate many body functions related to metabolism, heart rate, body temperature, growth and development, and even brain function.

According to New U Life, thyroidinum is included in their blend to support thyroid health.

Regarding its effect on metabolism, oral thyroidinum supplementation did not lead to weight loss in fasting subjects.

More recently, thyroidinum 3X was found to improve weight loss and symptoms associated with hypothyroidism. However, it is important to note that these subjects were also on standard medical treatment for this condition.

Again, support for the transdermal use of this ingredient is lacking. While oral supplementation has been tested, they only seem to benefit those with low thyroid hormone levels.


New U Life offers a blend of ingredients that have not been extensively studied in human trials. Also, the majority of the available research has tested the short-term use of oral preparations.

As support for transdermal use in human subjects is lacking, conclusions regarding the safety of SOMADERM Gel can't be made at this point.

Injectable treatment with synthetic GH has been associated with joint pain, insomnia, headache, back pain, and muscle spasms, though it is generally considered well-tolerated. Animal studies have demonstrated that concentrations may be similar when applied transdermally, so similar side effects may occur with SOMADERM Gel.

While we weren't able to locate any research that tested the safety of glandula suprarenalis, a study reviewed 12 different OTC adrenal support supplements and found that they may contain hidden steroid and thyroid ingredients that can be harmful.

Thyroidinum 3x was safely tested in those with hypothyroidism. However, oral formulations were used in this study.

There is no indication that this supplement is capable of boosting hormone levels into dangerous levels, but it is a good idea to be aware of signs and symptoms should they arise.

Signs of Excess GH

  • Enlarged facial features
  • Enlarged hands or feet
  • Thickened, oily skin
  • Fatigue
  • Swelling and muscle pain
  • Joint pain

Sign of Adrenal Hyperactivity

  • Increased fat accumulation around your midsection
  • Round face
  • Fatty hump on your neck
  • Thin skin
  • Weak bone and muscles
  • fatigue

Signs of Thyroid Hyperactivity

  • Irritability
  • Increased heart rate
  • Hand tremors
  • Weight loss
  • Diarrhea
  • Excess sweating

It is best to speak with a doctor before using SOMADERM Gel, especially if you feel your GH levels may be low. As a delicate interplay of multiple systems regulates your hormone levels, it is not a good idea to manage them on your own.

Identify the underlying cause first and then collaborate with your doctor to outline the best plan of care.

The Cost

New U Life offers SOMADERM Gel directly from their website.

You can purchase your bottle for $169.99 + shipping. If you opt for the subscription service, you'll save $20 and receive free shipping. This service requires a membership.

New U Life does back your purchase with a 60-day guarantee, though they apply a 25% restocking fee to orders of 2 bottles or more. According to their site, you must contact support before returning opened products.

For membership inquiries or to initiate returns, New U Life suggests calling 925-274-5000 or emailing support@newulife.com.

What Are the Alternatives to SOMADERM Gel?

For now, it seems as though New U Life has the market cornered regarding OTC synthetic GH gels.

However, supplements that claim to boost GH levels or provide the benefits of this hormone are numerous.

SeroVital is one example.

SeroVital offers a blend of amino acids and extracts that are alleged to boost GH. It is available directly from the products page. Additional retailers carry the supplement:

  • Costco: $94.99 (160 count)
  • GNC: $69.99 (120 count)
  • Ulta: $69.30 (120 count)
  • Amazon: $93.22 (160 count) and $89.99 (148 count)

While you'll pay less than half of the price for SOMADERM Gel, don't expect an abundance of scientific support for the ingredients. SeroVital's blend seems to boost HGH levels though no other benefits were seen.

Whether topical or oral formulations, it is best to speak with your doctor before attempting to manage hormone levels on your own.

The Bottom Line

New U Life's SOMADERM Gel offers 3 ingredients that all lack strong scientific support for their ability to offer benefits when applied transdermally.

There is evidence that injectable forms of synthetic GH formulations can be effective in managing GH deficiency, but this does not infer that diluted transdermal preparations will be efficient in those with normal levels.

New U Life claims that a key benefit of their product is avoiding the adverse effects commonly associated with medical management for low GH. However, without studies investigating transdermal application, no conclusions can be drawn regarding the safety or effectiveness of SOMADERM Gel.

In fact, you may be at risk for boosting hormone levels into dangerous ranges if levels are already adequate.

When you figure-in the high cost, suspect return policy, and potential for harm, it is best to stay away from this product.

Never manage hormone levels on your own - always speak to a physician about the symptoms you may be experiencing.

Customer Reviews

3.6 Stars out of 44 Reviews
5 Star:56% 4 Star:4% 3 Star:2% 2 Star:11% 1 Star:25%
64% Recommend This Product
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Posted on Mar 2, 2023


By Julie W., New Braunfels, TX, Verified Reviewer

Within 3 days of using the gel, I noticed my brain fog was gone and I was more focused. Then I noticed I was remembering things easier (short-term memory). Then started sleeping better and not needing a sleep aid. Energy level has improved. I’m one month in and haven’t seen other benefits than the ones listed above. I know the longer you are on it, the more benefits that will come.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Better memory retention

Better focus

More energy

A little pricey

Helpful Review? 1 Person Has Voted

Posted on Mar 9, 2021

It sucks, wouldn't recommend.

By Joseoh b., Worcester, MA, Verified Reviewer

Scam. It doesn't work. The people giving it 5 stars just think it works. It's like giving a drug addict a placebo and all of a sudden their symptoms are gone. No wonder why they don't stand behind their product. It sucks! Has done nothing for me but made me wash my hand a few extra times a day. Wouldn't recommend. Worst $169.00 I ever spent!

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

No “pros” were specified in this review

Price is ridiculous for a scam

Used all of it, wish I didn't, I want my money back

Telling friends about it

Helpful Review? 4 People Have Voted

Posted on Aug 7, 2020

Wish I had discovered it sooner!

By Charlynn K., Medicine Hat, Alberta, Canada, Verified Reviewer

I was introduced to this product by a relative in the U.S. I was following a Testimonial page on Facebook for a while and really liked what I was hearing! As it wasn't available in Canada at the time, she would mail me a bottle every month! I've been using it for 1 year this month! I am so excited that it has now become available in Canada!

I have been using it just as directed, 2 pumps in the morning and 2 in the evening, weekends off! Drinking lots of water with it as well.

I played around with the evening time a bit, and found that I needed to take it by around 6 pm at the latest to start. The gel has really given me better sleep at night, but because it is also good for energy, you don't want to take it too late! Now I can take it later and it doesnt cause an issue.

I am feeling so good on this gel!

Length of Use: 6–12 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

I love, and really was this first thing I noticed, the way it has given me an internal calmness, I don't feel as anxious as I did before


Energy and focus


Helpful Review? 10 People Have Voted

Posted on Oct 31, 2019

Wished I would had known sooner!

By Patricia C., Saskatchewan, Canada, Verified Reviewer

Golden years with a Golden product. I am 59 years young...been faithfully on the gel since August 21, 2019. Love, love, love this gel. It has changed my life. Being allergic to wheat and dairy products for over 20 years, I have felt so crappy and felt like I had no life left and thought my growing old was going suck...But then I discovered the gel...Wow, wow, wow! I am getting my life back, feeling young inside, energy like I have never had in a while...better mood, better sleep, no more brain fog or upset stomach, no aches and soreness, no more headaches, smoother skin, noticeable loss in inches, my pants are feeling looser...Can't wait to see more benefits! All of my symptoms that were aligning me are going away. Thank you for making a product that finally WORKS! And yes, I was skeptic at first but I am glad I decided to try it. If you are on the fence about this product, don't be, you have nothing to lose but everything to gain. What are you waiting for? I say try it, then talk about it. Just don't knock until you give it an honest try...give it at least 6 months to see the true benefits though. You won't be sorry you did!

Bottom Line: Yes, I would recommend this to a friend

Helpful Review? 8 People Have Voted

Posted on Oct 3, 2019

It is a scam

By Connie J., Booneville, AR, Verified Reviewer

My sister was convinced that my long term use would help correct my low thyroid issue but over a year after I started faithfully using Somaderm, I had my blood work done and there was no change in my thyroid reading levels.

Bottom Line: No, I would not recommend this to a friend

Helpful Review? 22 People Have Voted

Posted on Sep 3, 2019

Total scam

By Jen H., Utah, Verified Reviewer

This product is a total scam. I was promised a 100% customer satisfaction if not a 100% money-back guarantee. I spent over $1K and received a little over $600 back. They know this is a crap product, that is why they don't stand behind it.

Bottom Line: No, I would not recommend this to a friend

Helpful Review? 16 People Have Voted

Posted on Aug 2, 2019

After 5 months

By Steven M., English Town, NJ, Verified Reviewer

I’m 51. I feel 35, look 35-38. Works wonders. Very pleased. No side affects at all. My sleep is better, I’m stronger, I have way less joint pain! People...I’m growing hair. I don’t expect to look like Fabio but holy cow! I wake a lot less to use the bathroom. Muscle mass is showing. I can go on for days! All I can truly say is try it. Less than 3 bucks a day...we waste that on coffee.

Bottom Line: Yes, I would recommend this to a friend

Helpful Review? 18 People Have Voted

Posted on Jul 24, 2019

I love the Gel!

By Lisa N., Arkansas, Verified Reviewer

I have used Somaderm for 7 continuous months. I started by using it every day twice a day and now use it 5 days a week. The gel is incredible but it does take time to work. After 1 month, fewer aches and pains, great sleep and increased energy. After 3 months, hot flashes were gone and hormones more balanced. More benefits than I can state here but you have to stick with it. One bottle lasts two months...try it!

Bottom Line: Yes, I would recommend this to a friend

Helpful Review? 17 People Have Voted

Posted on Jun 20, 2019


By Teja F., Texas, Verified Reviewer

I've been using the Somaderm Gel product for over a month now and the results are fabulous! Better sleep, better mood, fat loss, less pain, and better muscle tone. This is the BEST product I have EVER used. Period!

Bottom Line: Yes, I would recommend this to a friend

Helpful Review? 14 People Have Voted

Posted on Jun 20, 2019

Sadly disappointed

By Dina S., Virginia Beach, VA, Verified Reviewer

I was over the moon to hear of a friend's success with this product, so I tried it and went all in signing up as a member. Initially, I had instant success, with the relief of the hot flashes, but not long after, it seemed to just not work anymore. I decided to stick with it using the product twice daily for 6 months. There was no change for the better and now I have an overabundance of product that I will not use and refuse to sell based on my results. I can't in good faith sell a product I cannot back personally. I'm on hold right now with the company in hopes to get my money back for 5 unopened bottles (4 auto ship and 1 remaining from my initial order). Here's hoping they will do the right thing!

Bottom Line: No, I would not recommend this to a friend

Helpful Review? 23 People Have Voted

Posted on Jun 17, 2019

Love the gel!

By Steve H., Odessa, FL, Verified Reviewer

I've been on the gel for 6 months now and love it. Everyone expects results in one day and it just doesn't happen with any product. I feel like a young kid again, full of energy and sleep like a baby. If you're one that wants it to work on day one, please don't order it. If you plan to give it at least 3 months, do it and you won't regret it.

Bottom Line: Yes, I would recommend this to a friend

Helpful Review? 14 People Have Voted
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