Genucel Review: Important Things to Consider Before You Buy

Manufactured by Chamonix, Genucel is a line of clinically tested anti-aging products based on the company’s Swiss apple Plant Stem Cell Technology, in addition to other essential ingredients.

We’re told that Genucel’s powerful formulations can help you achieve everything from reduced eye bags and puffiness to a brighter, more youthful complexion. In fact, Chamonix claims that some Genucel products can deliver results in as little as 12 hours!

And to top it off, Genucel products are equally effective for both men and women.

Now, Genucel’s main website might have appeared pretty cut and dry at first glance, but if you dig under the surface a bit, it’s actually a little more complicated that it seems.

To help simplify things, we’ll start off by discussing the offer you’ll find at Then, we’ll talk more about Genucel-branded products listed on Chamonix’s main website.

What’s Included in the Genucel TV and Radio Package?

At the time of our research, Chamonix only offered a TV and Radio package on the primary Genucel website, which included the following four products:

Genucel Plant Stem Cell Eye Therapy

The Eye Therapy formula uses plant stems cells from the Malus Domestica apple species to help your skin look younger.

Chamonix claims that one of Eye Therapy’s main ingredients, Eyeseryl, was clinically shown to reduce under eye puffiness by up to 70% within 15 days, and by up to 95% by the end of testing. In fact, we’re told Eye Therapy’s formula features double the concentration used in the clinical studies!

Additional ingredients include:

Genucel Immediate Effects

Chamonix tells us that Genucel Immediate Effects utilizes Relaxoderm Technology, along with other safe, natural ingredients, to smooth away the appearance of lines and wrinkles around the eyes.

We’re also told that Immediate Effects underwent a clinical trial in 2006, which resulted in a “visual reduction of fine lines and wrinkles” of about 28.81%, without adverse side effects or unexpected reactions.

Esotique-RF with ​​Matrixyl

According to Chamonix, Esotique-RF with Matrixyl (Protein Polypentapeptide) is the company’s best-selling—and most effective—anti-wrinkle treatment, because it will make your skin feel healthier and look more youthful.

Key ingredients include:

We’re told you need to apply Esotique-RF to a clean face twice daily. If applying Esotique-RF on top of another anti-aging product, make sure it’s fully dry beforehand.

L’essence with Vitamin C Advanced Neck Treatment

Using certified organic purified water, green tea (and the antioxidants it contains), vitamin C, safflower oil, aloe leaf juice, and a proprietary Calendula extract, L’essence promises to help tighten skin on the neck area and leave it feeling “silky smooth.”

Chamonix recommends generously applying L’essence to the neck and décolletage in the morning and evening.

The Complete Genucel Product Line

Overall, there are six Chamonix products bearing the Genucel name (few of which we’ve already discussed above):

Genucel Deep Firming Serum with Plant Stem Cell Technology

Genucel DFS’ active ingredient is 7.5% vitamin C, which we’re told is delivered to the skin via Liposome Technology and “the latest in plant stem cell technology.”

Chamonix claims their DFS formula delivers “astonishing luxury and effectiveness” that can provide the appearance of flawless skin, 24-hour hydration, and smooth texture.

To accomplish this, you’re instructed to apply a few drops of Deep Firming Serum onto your fingertips, and then massage into your cleansed face.

Genucel XV Plant Stem Cell Therapy Anti-Wrinkle Treatment

Along with their Plant Stem Cell technology, calendula flower, and essential oil extracts, Genucel XV adds peptides, hyaluronic acid, CoQ10, and an Enzyme Activation group containing vitamins B3 and B6.

As a result, we’re told you can expect “outstanding moisturizing and anti-aging effects” that’s made without mineral oil, petroleum byproducts, or pharmaceutical preservatives that might cause sensitivity or clog pores.

Genucel Dark Spot Corrector

Whether on the face, hands, shoulders, arms, or anywhere else on the body, Genucel’s Dark Spot Corrector promises to lighten their appearance, brighten skin, and visibly even skin tone.

To accomplish this, Dark Spot Corrector contains four key ingredients:

Genucel Plant Stem Cell Therapy Exfoliating Masque

While no ingredients are listed on the Chamonix website, Genucel’s Exfoliating Masque promises to feature a new formulation that delivers “maximum nourishment and moisture retention.”

To use, we’re instructed to apply in a circular motion for 2-3 minutes and rinse with water, 2-3 times per week.

Clearly, most of Genucel’s formulations place a great deal of emphasis on plant stem cells. But what’s the deal with them anyway, and can they really deliver results?

We’ll answer this question in a second, but first, we need to cover some quick basics.

Plant Stem Cells vs. Human Stem Cells

Whether in humans or in plants, stem cells are undifferentiated. This means they can become any other type of cell in the organism. However, there are some key differences between the two.

For example, a plant’s stem cells not only have the ability to become any type of tissue, but they also have the ability to become an entire organism. This is known as totipotency.

Human stem cells, on the other hand, can’t “give rise to an entire functional organism” (at least not after four days of embryonic cell division), but they can still become any kind of human tissue. This is known as pluripotency.

Well, this isn’t exactly the whole picture, since human stem cells can be further classified into:

  • Embryonic Stem Cells – These stem cells are the pluripotent ones we just discussed, as they can become any type of tissue. While the potential medical benefits of these stem cells might be limitless, they’re a hot topic of debate, since the embryo is destroyed in the process.

  • Adult Stem Cells – Adult stems cells are multipotent, which means they can only become a tissue of the same type. So, a heart muscle stem cell could only become a heart muscle cell; a skin cell another skin cell, and so forth.

Given the potential concerns surrounding embryonic stem cells, along with the greater developmental ability of plant stem cells, is there any benefit to applying them to your skin?

Are Plant Stem Cells Effective on Human Skin?

As it turns out, this largely depends on how you define “effective.” Let’s explain.

First, another similarity between plant and human stem cells is that they’re extraordinarily fragile. In other words, if you put them directly into a cream, it’s likely that the majority (if not all) would perish before finding their way to your home.

Second, even if they did survive the journey, your skin is exceptionally good at keeping things out. As a result, stem cells are far too big to pass through the epidermis (the outer layer of the skin), so they’ll just sit there until evaporating or being washed off at the end of the day.

Here’s a quote from a 2015 USA Today article that pulls these first two thoughts together nicely:

“Stem cells that are in contact with skin are not really alive anymore,” said Margaret Foster Riley, a law professor and expert on food and drug law at the University of Virginia. “So I don’t really see how a stem cell product is working on the skin. I suppose some of them may actually work in a way that cosmetics work otherwise, because of moisturizing capability. But it’s not stem cell capability that’s working there to the degree we know how stem cells work.”

Third, even if these plant stem cells could survive their journey and be absorbed through the skin, authority websites indicate there is very little high-quality clinical evidence showing that plant stem cells in general—or the Swiss apple ones in Genucel’s lineup—can reliably provide anti-aging benefits in humans.

But, What About Genucel’s Other Ingredients?

Here again, your definition of “effective” is going to play a big role in answering this question.

For example, Matrixyl is a proprietary ingredient the manufacturer claims can boost collagen, although authority websites indicate there’s limited clinical evidence supporting this.

The natural caffeine in Plant Stem Cell Therapy’s formulation might help temporarily tighten skin, and the topical application of hyaluronic acid can increase cell turnover and boost moisturization.

» See Also: How to Test a Beauty Product to See If It Really Makes a Difference

However, these are very common ingredients in OTC beauty treatments, so there doesn’t appear to be anything revolutionary here.

Finally, collagen is the most abundant protein in the human body and acts as an underlying foundation for strong skin, but—like the stem cells we already discussed—it can’t be absorbed by skin and therefore provides little more than moisturization.

How Much Do Genucel Products & Packages Cost?

Genucel’s TV and Radio Special is priced at $139.95, plus free S&H, which will save you over 50% off the list price. You’ll receive:

  • 2 Tubes of Genucel Stem Cell Eye Therapy
  • Genucel Immediate Effects
  • Esotique-RF with Matrixyl
  • L’essence Advanced Neck Treatment

Important note: If you order the TV and Radio Special, you’ll be signed up for Chamonix’s Preferred Customer Program.

Here, you’ll receive a fresh supply of all these items once per month and your credit card will be charged $139.95 each time. You can contact customer service to cancel or change your shipments at any time.

On the other hand, if purchased individually on Chamonix’s main website, you’ll pay:

  • Genucel Stem Cell Eye Therapy: $89 (BOGO $133.50)
  • Genucel Immediate Effects: $79 (BOGO $118.50)
  • Esotique-RF w/Matrixyl: $99 – $247.50
  • L'essence Advanced Neck Treatment: $93.50 – $140.25

The remaining products in Genucel’s lineup are priced at:

  • Genucel DFS: $92 – $138
  • Genucel XV: $110 – $297
  • Dark Spot Corrector: $129 – $193.50
  • Exfoliating Masque: $69 – $103.50

All Chamonix products come with a 60-day money back guarantee, less S&H charges. However, remember that there are no refunds on the Preferred Customer Program. Here’s how the company puts it:

“Only merchandise exchange [is available] with exception to your first initial sign up order. Once a recurring shipment is sent out, the package is non-refundable and can only be used towards company credit.”

In order to request a refund or adjust/cancel your Preferred Membership, you’ll need to contact customer service at (800) 754-6211 or

Do Genucel Products Come With Solid Customer Reviews?

Here on HighYa, 44 readers provided feedback about their Genucel experiences since our original investigation, giving it an average rating of 1.7 stars, with most complaints referencing no noticeable results.

Other common complaints referenced side effects like dried-out skin (one even claimed to have experienced an allergic reaction), along with difficulty obtaining refunds and/or canceling recurring shipments.

Outside of this, there was little-to-no customer feedback on third-party websites about Genucel at the time of our research.

From a company perspective, Chamonix held an A+ rating with the Better Business Bureau, with 44 closed complaints (as of 10/28/16).

There, most complaints cited repeated high-pressure sales tactics, problems obtaining refunds, difficulty canceling recurring shipments, and unhelpful customer service.

We’ve admittedly covered a whole lot of territory here, so let’s go ahead a bring it everything together as we wrap up.

What’s the Bottom Line About Genucel’s Anti-Aging Products?

We’re not medical experts here at HighYa, and we didn’t order any Genucel products or test them firsthand. However, like any other consumer, we can use publicly available information—including feedback from authority websites like WebMD—to make an educated decision.

From this perspective, the manufacturers behind many of the proprietary ingredients in Genucel’s formulations, like Matrixyl and Eyeseryl, promote the fact that they’re clinically proven.

Unfortunately, these clinical trials largely aren’t available for public review, so there’s no way to verify their findings.

On the other hand, Chamonix does provide the ability to review the details of their 2006 study for Immediate Effects, which is certainly positive. However, it appears to be a standalone study that wasn’t double-blind, so it’s a long shot to say that it’s clinically “proven” to work as advertised.

According to these same authority websites, we also learned that plant stem cell technology—at least from a topical anti-aging perspective—doesn’t seem to hold a lot of promise, either.

Taken together, only you can decide whether or not this information means Genucel’s products are worth the relatively high price, or that you should keep looking.

If you feel like giving them a shot, though, it’s positive that Chamonix stands behind their products with a 60-day refund policy. Although based on common customer complaints, you might experience some difficulty processing one.

» Recommended Reading:

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Read 44 Genucel Customer Reviews and Complaints

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Average Consumer Rating: 1.7
Rating Snapshot:
5 star: 6 4 star: 1 3 star: 1 2 star: 1 1 star:  35
Bottom Line: 16% would recommend it to a friend
Showing 1-11 of 44
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  • 20 out 22 people found this review helpful

    It's a scam

    • Henderson, NV,
    • Apr 10, 2019
    • Verified Reviewer

    Try to cancel your order. You can't. They just keep sending more and more product. When you try to cancel, they have to call you back and then they don't. Save your money. The product stinks.

    Bottom Line: No, I would not recommend this to a friend

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  • 26 out 28 people found this review helpful

    Genucel doesn't work

    • Silver Grove, KY,
    • Mar 1, 2019
    • Verified Reviewer

    I bought a set of Genucel on eBay. The kit includes the instant eye treatment, the stem cell eyes treatment, and the neck treatment. The instant never has worked. Anyway, I have been using the treatments for three weeks now twice a day. I thought that if I used it, it might eventually get rid of the bags under my eyes, which are not severe but, they are there. Absolutely nothing, NOTHING has happened. I bought it on eBay as it was only $ 49.00. I'd be really sick if I had spent over a hundred!

    Bottom Line: No, I would not recommend this to a friend

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  • 38 out 38 people found this review helpful

    Watch out for the auto renew rip offs.

    • Arizona,
    • Feb 22, 2019
    • Verified Reviewer

    I purchased a package online and wasn't aware that you are automatically put onto an auto renew status. I received an update from my credit card that a purchase was just made so I called in immediately as I did not want to make another purchase at the time and told them I'd like to cancel the auto renew and be reimbursed for the order that was just placed on auto renew. I was informed that the order was already sent even though I was just charged not an hour before and they could not refund what they charged me. I'm now out $200. Terrible customer service for someone who supposedly guarantees their product. Unbelievable! I would not recommend a company with scams like this to anybody!

    Bottom Line: No, I would not recommend this to a friend

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  • 31 out 31 people found this review helpful

    Read the fine print

    • Colorado,
    • Feb 17, 2019
    • Verified Reviewer

    I thought I was taking advantage of a one-time holiday special advertised on the radio. And ordered a package special for $164.00.

    Low and behold...two months later my credit card was charged another $164.00 for a box of little tubes and jars of creams that are supposed to make you look younger.

    Save your money. If you do order this stuff, don't forget to cancel in a week or you'll keep paying.

    Bottom Line: No, I would not recommend this to a friend

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  • 33 out 33 people found this review helpful

    Beware of subscription

    • Tallahassee, FL,
    • Feb 4, 2019
    • Verified Reviewer

    I ordered the product once and was considering doing it again when suddenly they took money out of my bank account. They would not give me my money back and said it was part of a subscription.

    Bottom Line: No, I would not recommend this to a friend

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  • 113 out 113 people found this review helpful


    • Pennsylvania,
    • Jun 5, 2018
    • Verified Reviewer

    I purchased this product because it came highly recommended and it did work a bit, although the regimen is ridiculous. My complaint lies in the subscription program. I'm sure I didn't see this anywhere when I ordered the product, and if I did, I would NOT have signed on to a subscription - I never opt for these things. I called and canceled the program and found out that the products I received (that I don't even use) are non-refundable. Even though the product is ok, it's expensive, and I likely wouldn't have purchased it again because of the expense. However, it's this kind of sneaky BS (forcing people into a non-refundable subscription program) that will stop me from recommending it to anyone. In fact, I will now tell everyone I know NOT to order it.

    Bottom Line: No, I would not recommend this to a friend

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  • 21 out 57 people found this review helpful

    Works for me

    • Cheyenne, WY,
    • Mar 7, 2018
    • Verified Reviewer

    Even though I used Genucel products for a few years, I canceled, without a problem, just because I thought I'd try something different from a local high-end department store. I recently went back to Genucel because Genucel worked better for me than the high-priced skin care products I was buying from the department store. I like Genucel.

    Bottom Line: Yes, I would recommend this to a friend

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  • 90 out 92 people found this review helpful

    Product does nothing

    • Midway City, CA,
    • Feb 4, 2018
    • Verified Reviewer

    I have been using the introductory package which includes eye cream, neck cream, under eye puffiness cream, upper lid cream, face cream, and the initial oil to be rubbed in before starting. I have found the following:

    1. This regimen is time-consuming.

    2. It does positively nothing. I have used them for a month.

    When I ordered, I was told to get my return and charge credited, I needed to return in two months, however, the insert with the packaging says four months.

    Also, the containers are so small that you need a magnifying glass to read what each one is for, and I can usually read without glasses.

    Big disappointment. And I just hope they don't give me a problem when I return the rest.

    Bottom Line: No, I would not recommend this to a friend

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  • 19 out 41 people found this review helpful

    Genucel works well for me

    • Denver, CO,
    • Oct 3, 2017
    • Verified Reviewer

    I'm not sure about long-term, but I've been using Genucel for four months now, and it is doing a great job. I've been out and about and feeling good and my skin looks much firmer.

    My personal rating - a 10!

    Bottom Line: Yes, I would recommend this to a friend

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  • 73 out 74 people found this review helpful

    Poor product - no results as claimed

    • Gatlinburg, TN,
    • Jul 22, 2017
    • Verified Reviewer

    The products that were sent to me had absolutely no affect as claimed. There were no signs of correcting the puffiness, and I used it for over one month and they kept charging my credit card. I finally canceled the order. They are using all the money that poor people fell for on advertising more and more.

    It's a shame that even Shawn Hannity endorses this product and claims he uses it, now I have even less respect for him and what he advertises on his shows. Unfortunately I, like all these other people that have given this product a poor rating, will have less respect for any products or claims, just another money making gimmick!

    Bottom Line: No, I would not recommend this to a friend

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  • 87 out 88 people found this review helpful

    Proceed with caution!

    • Barrington, IL,
    • May 1, 2017
    • Verified Reviewer

    I received my first supply of Genucel on a Friday, used it that night, twice on Saturday and on Sunday morning. By Sunday evening my entire eye area was red and irritated and so I did not use Genucel that night. Monday morning I awoke looking like a prizefighter after a long match. I saw my dermatologist and he put me on steroid medication and hydrocortisone.

    The sad thing was that I decided to try Genucel to improve the look of my eyes for my son's upcoming wedding, now I'm just hoping that my face looks normal by next weekend! There are no warnings to try Genucel in a small inconspicuous area of your face (temple, maybe?) before you apply it to your entire eye area and realize that you are highly allergic to one or more of its "plant extracts". I called and told the rep what had happened, and returned everything but still had to pay for shipping- just happy to get rid of it!

    Please be cautious. I have never had a reaction to any eye cream before, and I've tried a lot at every price point.

    Bottom Line: No, I would not recommend this to a friend

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