About Heal-n-Soothe

By HighYa Research Team
Published on: Feb 22, 2018

By combining 12 natural, powerful pain relievers and anti-inflammatory ingredients with enzymes, Heal-n-Soothe is a dietary supplement that promises to help promote healing and recovery, reduce muscle discomfort, and support healthy circulation and immune response.

All you have to do is take at least one capsule (up to four times daily, if needed), 30 minutes before or 60 minutes after meals, and the company reports the supplement’s ‘systemic enzyme therapy’ could begin delivering results.

But is Heal-n-Soothe really "Mother Nature's feel-good formula,” as advertised on the website? Does it actually contain ingredients that have been clinically proven to work?

We’ll explore important questions like these in this article, starting with the topic of enzymes.

What Is Systemic Enzyme Therapy and Is It Effective?

While we didn’t encounter much detailed information about systemic enzyme therapy during our research, writing for Science-Based Medicine, Scott Savura defines it as consuming enzymes orally “with the intent of whole-body effects."

Specifically, the therapeutic approach is often promoted as a way to address inflammation, which Scott reports is a “host of complex physiologic processes mediated by the immune system,” often expressed as redness, heat, pain, and swelling.

From a clinical perspective, he points out that enzyme therapy “can be science-based,” since it’s often used to treat pancreatic disease and cystic fibrosis, but he tempers this by emphasizing that “those are not uses where the enzymes need to be absorbed from the gastrointestinal tract,” since they’re often injected in very large doses.

Comparatively, “the concept of giving enzymes orally, and achieve meaningful therapeutic effects in the body, is one with a considerable number of drug design hurdles,” he says.

As a result, “until better evidence appears to demonstrate the efficacy and safety of systemic enzyme therapy,” he emphasizes, “their use can’t be considered science-based.”

With this core information in mind, which enzymes will Heal-n-Soothe’s formula deliver, and what does the clinical evidence have to say about their efficacy?

Taking a Closer Look at Heal-n-Soothe’s Ingredients

According to the supplement facts label listed on their website, Heal-n-Soothe contains the following ingredients:

  • Boswellia Extract 150 mg
  • Citrus Bioflavonoids 90 mg
  • Ginger Extract 90 mg
  • Mojave Yucca (root) 90 mg
  • Turmeric 60 mg
  • Alpha Lipoic Acid 50 mg
  • Rutin 30 mg
  • Devil’s Claw Extract 30 mg
  • Systemic Enzyme Blend 7540 mg: Protease AM 225 AP, Bromelain 6M FCCPU, Protease 6.0 60,000 HUT, Alkaline Protease 12,000 USP, Papain 1.5M FCCPU

Before diving in, it’s important to point out that the HighYa team doesn’t have a scientific background when it comes to the biological effects of dietary supplements.

This means that when reporting on whether or not an ingredient is effective for a specific claim, we rely on the cumulative clinical evidence reported by sites like the Natural Medicines Database, Examine.com, and WebMD.

According to these sites, some studies indicate that taking 100-333 mg of certain Indian frankincense (Boswellia serrata) extracts daily can improve joint pain and mobility by anywhere between 32 and 65 percent in those with osteoarthritis.

Similarly, taking between 250 and 500 mg of ginger extract, three to four times daily, has been shown in some studies to reduce arthritis-related hip and knee pain, as well as standing and walking pain and stiffness in those with osteoarthritis.

In some instances, it worked about as well as 400 mg of ibuprofen, while in others it did not.

500 mg of turmeric (which contains an active chemical called curcumin), when taken two to four times daily for two to six month, has been shown to reduce pain and improve function in people with osteoarthritis.

In some instances, it reduced pain as much as ibuprofen, but didn’t reduce inflammation as much as the drug diclofenac.

Rutin, whether contained in Heal-n-Soothe or another dietary supplement, is a type of plant pigment (flavonoid) that might have antioxidant and anti-inflammatory effects.

And when combined with 288 mg of trypsin and 540 mg of bromelain, taking 600 mg per day has been shown to “be about as effective as the medication diclofenac (Voltaren) in relieving pain and improving knee function in people with osteoarthritis.”

Another potentially helpful ingredient related to osteoarthritis is devil’s claw. In some studies, taking between 400 mg and 2.6 grams per day for between two and four months has been shown to help decrease pain, often in the hip and knee.

Finally, while we learned earlier that a combination of rutin and bromelain might have some osteoarthritis-related benefits, these same sites didn’t indicate that it—or any of the remaining enzymes or ingredients found in Heal-n-soothe—will deliver on the manufacturer’s claims.

Potential Side Effects Related to Heal-n-Soothe’s Ingredients

The disclaimer at the bottom of Heal-n-Soothe’s website emphasizes that some of these ingredients could thin blood, and that the supplement shouldn’t be taken by anyone who’s allergic to pineapple or papaya, or by those who are pregnant or nursing.

They also note that it’s possible to experience side effects (no dosages or other circumstances noted) like sinus drainage, gas or loosening of the stool, and decreased blood pressure.

WebMD and the Natural Medicines Database report that in some instances (again, no dosages or other circumstances provided) turmeric can cause stomach upset, nausea, dizziness, or diarrhea.

They also tell us that while devil’s claw is possibly safe when used for up to one year and that the most common side effect is diarrhea, “other possible side effects include nausea, vomiting, stomach pain, headaches, ringing in the ears, loss of appetite, loss of taste,” and allergic skin reactions.

How Much Does Heal-n-Soothe Cost?

Heal-n-Soothe is only available directly from the manufacturer, through the following two options:

  • One-Time Order (90 vegetarian capsules): $59
  • Free Trial: $9.95 S&H

If you choose the trial option, you’ll be billed the full price of $49.95 after 14 days have passed, and will continue receiving a new bottle each month and paying $49.95 each time, until you cancel.

Living Well Nutraceuticals offers a 90-day refund policy on all Heal-n-Soothe orders, less S&H, which you can request by calling (888) 231-9901 or sending an email to info@livingwellnutraceuticals.com.

Are There Any Online Heal-n-Soothe Customer Reviews?

Heal-and-Soothe was previously available through Amazon, where more than 50 customers had given the supplement an average rating of 3.5 stars.

Common compliments revolved around reduced pain and inflammation, while complaints often referenced no results, difficulty obtaining a refund, and side effects like digestive upset.

As far as the company, Heal-n-Soothe is distributed by Living Well Nutraceuticals, based out of Glendale, CA.

They weren’t listed with the Better Business Bureau as of 2/21/18, although the company manufactures several other dietary supplements, including Rub on Relief natural pain cream, SleepZyme sleep aid, and ThinMist weight loss spray.

Heal-n-Soothe vs. Other Systemic Enzyme Therapy Supplements

Browsing online marketplaces like Amazon and Google Shopping, we encountered several popular enzyme supplements competing with Heal-n-Soothe:

Supplement Price Active Enzyme(s) Other Ingredients?
Heal-n-Soothe $49 - $59 Bromelain, Papain Boswellia, bioflavonoids, ginger, yucca, turmeric, ALA, rutin, devil's claw
NOW Super Enzymes $11+ Bromelain, Ox Bile, Pancreatin, Papain No
Doctor’s Best Proteolytic Enzymes $21 Bromelain, Papain, Amylase, Lipase, Serratiopeptidase, Lipase Neutral, fungal, and bacterial protease, rutin
Enzymedica Repair Gold $30+ Bromelain, Amylase, Catalase, Papain, Serratiopeptidase, Lipase No
Source Naturals Daily Essential Enzymes $42 Pancreatin, Acid-Stable Protease, Lipase, Amylase, Amyloglucosidase, Cellulase, Lactase No
Wobenzym N $25+ Pancreatin, Papain, Bromelain, Trypsin, Chymotrypsin, Rutoside No

Given all these options, formulations, and price points, what’s the best way to figure out which one—if any—is right for you?

As we always emphasize, start by talking with your doctor. They can help diagnose the underlying cause of your pain, discomfort, and inflammation, and then recommend a science-based treatment from there.

If they recommend pursuing a dietary supplement, after writing about hundreds of different formulations over the years, we’d recommend only doing business with manufacturers who:

  • List all of their ingredients, including dosages, with no proprietary blends (which don’t list dosages)
  • Support their claims with quality clinical evidence
  • Back their products with at least 30-day refund policies and don’t charge restocking fees

Related: Follow These Steps to Understand a Dietary Supplement’s Claims

Does this mean you should do business with Living Well Nutraceuticals and place an order for Heal-n-Soothe?

Our Final Thoughts About Heal-n-Soothe

Pain is a complex process, and it will take the help of a physician to narrow down what’s causing yours, and then prescribe a viable treatment. So—again—whether you're considering Heal-n-Soothe or another dietary supplement, they're perhaps your best resource for achieving the most bang-for-your-buck.

With this in mind, based on what we learned earlier, while systemic enzyme therapy as a whole might not seem to have much clinical support, several of Heal-n-Soothe’s individual ingredients are reported by sites like Examine.com and WebMD to be possibly effective for osteoarthritis-related benefits.

Which could be positive, as long as this is the cause of your pain. If not, you might be flushing your money down the drain.

Pro tip: However, many of these ingredients (ginger, turmeric, rutin, and devil’s claw) aren’t found in the same dosages in Heal-n-Soothe as referenced in supporting clinical trials.

Even when referencing the same source of pain, the reality is that everyone’s body is different, so what works for one patient might be a total fail for another.

For this reason, it’s positive that Living Well Nutraceuticals seems to stand behind Heal-n-Soothe with a 90-day refund policy—just keep in mind that you’ll have to pay to send the bottle back if you’re dissatisfied.

» Read Next: Do You Need to Take Vitamins or Dietary Supplements?

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Read 14 Heal-n-Soothe Customer Reviews and Complaints

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Average Consumer Rating: 2.8
Rating Snapshot:
5 star: 4 4 star: 2 3 star: 0 2 star: 3 1 star:  5
Bottom Line: 43% would recommend it to a friend
Showing 1-11 of 14
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  • 7 out 7 people found this review helpful

    No difference after second bottle

    • Aug 1, 2019
    • Verified Reviewer

    This is my second review. Finished first bottle with no results. Same with the second bottle. I will not buy any product online that touts miracles again. One bad apple spoils it for the rest.

    Bottom Line: No, I would not recommend this to a friend

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  • 18 out 19 people found this review helpful

    Very effective.

    • Auckland, New Zealand,
    • Apr 27, 2019
    • Verified Reviewer

    The product worked very well in my case. Helps me to keep under control my back and knee pain that I had in the past. Now I can move freely in the tennis court being able to be involved in many hours of tennis coaching a day, plus playing hard tennis 3+ hours, 3 times a week. I consider a great product to take which will improve your overall body mobility and overall body health.

    Best advice: Make sure you will take it exactly how they stated, 30 minutes before meals or 60 minutes after meals with plenty of water.

    Bottom Line: Yes, I would recommend this to a friend

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  • 26 out 31 people found this review helpful

    Extortion is bad

    • Lagos, Nigeria,
    • Apr 17, 2019
    • Verified Reviewer

    My mum has Arthritis that kept her indoors for three months. I read about Heal-n-Soothe online and I thought of buying for my mum. I made an order from Nigeria on February 25th, I was debited, but I have not seen the drugs yet, it has not been delivered.

    On March 25th I was debited tripled the previous amount. I was asked to block my account so it won't occur again. I refused. I said let me call back the institute for a refund. I did and no one picked all my call until I got exhausted.

    Please, I need a cancellation and I need my money refunded. Have mercy on the mercies and stop extorting money from the poor, it was out of pity I raised that money to get that drug and I have not seen it, yet I got debited twice.

    Bottom Line: No, I would not recommend this to a friend

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  • 23 out 24 people found this review helpful

    I love Heal-n-Soothe!

    • Huntington Beach, CA,
    • Mar 13, 2019
    • Verified Reviewer

    I was very hesitant to try this product. I have not felt better after exercise in over a year. I retired and thought I was getting old and I should go back to work. I could hardly get up from the chair or car or bed without feeling pain. I could feel the difference after taking it for two weeks. And for a bonus, I had this scar almost completely disappear. I had some stomach upset with the product, so I emailed them. Their customer service rep told me to rinse off the capsules before taking them and to drink a glass of water 15 minutes after taking the capsule. It worked. I can't take Advil or Tylenol for very long before it bothers my stomach. This is a fantastic product. My husband is starting to take it too. I hope it helps him too.

    Bottom Line: Yes, I would recommend this to a friend

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  • 37 out 44 people found this review helpful

    Heal-n-Soothe scam!

    • Spain,
    • Mar 7, 2019
    • Verified Reviewer

    What a scam! Took over a month for delivery, on my first week of taking capsules The Healthy Back Institute helped themselves to another $49.00 from my bank account without an email to request this. After just taking 4 capsules I had a migraine and a sharp stabbing pain behind my right eye. I emailed them the next day asking why they had stolen money from my bank account, I received the spill saying it's my fault, apparently, I had agreed to a subscription, and if I return unopened bottles within 7 days they will refund me the money they stole from my bank account. STAY WELL CLEAR.

    Bottom Line: No, I would not recommend this to a friend

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  • 43 out 50 people found this review helpful

    Heal-n-Soothe what?

    • Huntington Beach, CA,
    • Mar 1, 2019
    • Verified Reviewer

    I don't know what star rating to give, being that I've been taking it for a month now and no results. I tried calling to cancel any future orders because I'm on the 30-day trial period which automatically chargers you IF you don't CANCEL within 30 days. I called several times, put on hold, it's all a recording so you get nowhere. I was on hold the first time for 8 minutes, NOBODY. The same stupid music that is kind of disturbing. Second attempt I was hung up on, RUDE. Nobody comes to the phone, no mention of momentarily someone will be with you or experiencing a volume of calls, NOTHING. I get angry and impatient when having to hold for NOTHING, and to top it off this review may not ever be seen due to they scan every review so probable negative gets tossed. THANY YOU Heal-n-Soothe.

    Bottom Line: No, I would not recommend this to a friend

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  • 36 out 39 people found this review helpful

    Osteoarthritis on hands

    • Ohio,
    • Dec 10, 2018
    • Verified Reviewer

    My hand pain was so bad I could not hold hands with my husband or twist off caps on a beverage. Using this product, my hands are so much better, and I also use the lotion that came with the product. Both items are very helpful. I only take two tablets a day. So far I've recommended it to two of my brothers and my mom. They have their own issues, one had knee pain, other one had shoulder paid, and the third one had back pain. So far all four of us are happy with the product.

    Bottom Line: Yes, I would recommend this to a friend

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  • 57 out 64 people found this review helpful


    • Salt Lake City, UT,
    • Sep 18, 2018
    • Verified Reviewer

    Does not work! Another snake oil by a traveling sell man. Just another scam. It is a shame when people like me are in pain.

    Bottom Line: No, I would not recommend this to a friend

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  • 52 out 64 people found this review helpful

    Itching and hoarseness

    • California,
    • Sep 3, 2018
    • Verified Reviewer

    I was extremely excited by the rapid improvement in my knees. I had become embarrassed to get up when I was teaching in front of my students due to the grunts and groans and limitations in movement. After a week or two on Hea-n-Soothe my knees felt like had cushions and overall flexibility and movement was easier; specifically getting up and down to reach or perform minor household tasks.

    Then I realized that I was hoarse on a daily basis. I'm a professional singer and voice teacher, so this was a serious issue. I also read on some sight that papain, the papaya enzyme can actually cause throat damage, a very serious concern given my work, not to mention that it was annoying.

    Also, I started having itching throughout my body, including my hand, just little annoying tings, irritating at night especially. After discontinuing, I continue to have this side effect, though diminished.

    I still recommend the product to my friends because I considered the positive aspect miraculous, especially because I thinking knee replacements would be in my future.

    The company has been pretty responsive as I've asked for advice on these side effect issues and ultimately sent me a dietary book which supposedly has similar results over a longer period of time.

    A friend also told me that papain has been banned in surgical procedures because it could lead to major heart problems, another good reason to be wary, yet given my very positive results, I still tell my friends.

    I am, however, seeking other supplements and would like to find a medically trained professional for advice; perhaps online info will suffice. It's not fun have major movement restrictions, so I'm highly motivated.

    Bottom Line: Yes, I would recommend this to a friend

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  • 61 out 65 people found this review helpful

    Side effects

    • Victoria, British Columbia, Canada,
    • Aug 22, 2018
    • Verified Reviewer

    I began taking Heal-n-Soothe as suggested. I began with one capsule in the morning and one in the afternoon.

    I got a nosebleed the second day and for two subsequent days. I have never experienced spontaneous nosebleeds before. I stopped taking the product because it was the only change in my diet. The nosebleeds stopped.

    I tried again two weeks later with the same results. I don't have enough pillowcases to continue with it.

    Next miracle pain cure anyone?


    Bottom Line: No, I would not recommend this to a friend

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  • 49 out 51 people found this review helpful

    Very positive results from Heal-n-Soothe

    • San Clemente, CA,
    • Jun 22, 2018
    • Verified Reviewer

    I developed knee joint pain and aggravated osteoarthritis of my big toe after being prescribed Anastrozole (hormone inhibitor). I was not able to play pickleball without putting braces on my knees, couldn't get into some shoes due to swelling of the big toe, and couldn't walk beyond 2 miles versus the typical 5.5 - 6.5 miles I did regularly prior to the Anastrozole. I actually had surgery planned to address the pain in Stage 4 Rigid osteoarthritis.

    I started Heal-n-Soothe and noticed a difference by day 4. Ten days later I canceled the surgery on my big toe. I have been taking Heal-n-Soothe for 3 months now with no pain. I play pickleball approximately 3 - 5 hours a day, 3 times a week, and walk 6.5 miles once a week. I recommended it to several friends and 3 of the 4 have experienced the same reduction in pain as I experienced.

    Bottom Line: Yes, I would recommend this to a friend

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