About Instaflex Advanced

By HighYa Research Team
Published on: Aug 12, 2015

Formulated by Dr. David Katz, Instaflex Advanced is a dietary supplement that can help increase mobility in your knees, hips, shoulders, ankles, and hands by fighting inflammation and providing “advanced joint support.”

Compared to the original Instaflex (more about this shortly), the new Advanced formula is claimed to be 2X as powerful as glucosamine plus chondroitin, making it a simple, convenient, comprehensive solution that can help you feel a real difference in just 7 days.

In order to accomplish this, Instaflex Advanced is claimed to feature a highly concentrated compound of natural ingredients, including:

  • AprèsFlex 100mg – A concentrated form of boswellia serrata
  • Hyaluronic Acid 5mg – Forms “protective structures” around joint cells.
  • UC-II Collagen 40mg – A patented form of undenatured type II collagen.
  • Turmeric 200mg – Can lower histamine to fight inflammation, while helping the body produce cortisone to relieve pain.
  • Resveratrol 100mg – May help improve blood circulation.
  • Black Pepper Extract 5mg – Can help Instaflex Advanced’s other ingredients be more easily processed by the body.

In order to begin experiencing benefits with Instaflex Advanced, the manufacturer claims all you have to do is take one small, easy to swallow capsule per day. Instaflex Advanced is also claimed to be safe, non habit-forming, and drug-free, without any known allergic reactions or hazardous side effects.

Sure, the original version may be the #1 selling joint supplement at GNC, but will the new Instaflex Advanced really help you “get back to comfortable living,” or is it an overpriced placebo?

Before getting to that, let’s discuss the causes of joint pain.

What Causes Joint Pain?

Just like back pain or any other type of chronic condition, when your joints hurt, this is more of a symptom than it is a condition itself. Why? Because pain is your body’s way of telling you that something is wrong, but it doesn’t necessarily tell you specifically what’s causing the pain.

For example, joint pain can be caused by a wide variety of factors, including arthritis, bursitis, different types of strains and sprains, the aging process, and much more.

As such, if you’re suffering from arthritis, the anti-inflammatory properties of Instaflex Advanced might provide some level of pain relief. On the other hand, if you twisted your ankle a few weeks ago and are still dealing with some residual pain, Instaflex Advanced might be much less effective.

Considering all of this, if you’re suffering from recurring joint pain, the first thing you should do is speak with a physician, who can recommend an appropriate treatment based on your specific diagnosis.

Speaking of which, what kinds of conditions is Instaflex Advanced’s ingredients effective for?

The Efficacy of Instaflex Advanced’s Ingredients

The Instaflex Advanced website provides a brief overview of each of their ingredients (which is more than we can say about most of the nutritional supplements we’ve reviewed—they even provide a product label!), but let’s take a more in-depth look here.

Boswellia Serrata

Manufactured by PLT Health Solutions, AprèsFlex is a proprietary “next generation boswellia extract” that’s claimed to “improve the bioavailability and bioactivity” of Acetyl-11-keto-ß-boswellic acid (AKBA), while “helping protect against collagen degradation,” all of which can “support healthy joints and connective tissue.”

AprèsFlex’s manufacturer claims that the ingredient has been clinically shown to provide these benefits, but doesn’t provide a link to the study on their website. However, boswellia serrata (also known as Indian frankincense) is listed as “possibly effective” for treating osteoarthritis and for reducing joint pain by 32% to 65%.

Hyaluronic Acid

Like boswellia serrata, hyaluronic acid (HA) is listed as “possibly effective” for treating osteoarthritis, but only when injected directly into the joint. In other words, there is insufficient clinical evidence showing that oral HA supplementation can provide any benefits, whether related to joint health or anything else.

UC-II Collagen

UC-II Collagen, created by InterHealth Nutraceuticals, is claimed to be “a natural, safe and effective patented dietary ingredient consisting of collagen with undenatured type II collagen to support joint health.”

According to the company, the ingredient is clinically proven to work, the results of which were “presented at the Scripps 12th Annual Natural Supplements Conference in San Diego, CA.” However, they don’t provide a link to this study on their website.

With this said, there remains insufficient clinical evidence showing that any form of collagen type II supplementation can provide any benefits related to joint health or pain.

Turmeric

On the other hand, there is clinical evidence showing that turmeric is “possibly effective” for reducing osteoarthritis-related inflammation, although it may not provide any more relief than ibuprofen.

Resveratrol

Although there is some evidence indicating that resveratrol may help reduce inflammation, there currently isn’t enough to state with any certainty whether or not this is the case.

Black Pepper Extract (BioPerine)

Finally, BioPerine is proprietary ingredient manufactured by Sabinsa, which is derived from black pepper and is claimed to increase the bioavailability of other ingredients.

In other words, BioPerine will not provide any effects itself but may help your body better absorb all of the other ingredients contained in Instaflex Advanced.

Now that we’ve covered the efficacy of Instaflex Advanced’s ingredients, let’s take a look at possible side effects.

Instaflex Advanced Side Effects

Despite their somewhat shaky efficacy, Instaflex Advanced’s ingredients should be well tolerated by most users, with the most common cited side effects as digestive upset and headache.

Important note: Although the wording on the Instaflex Advanced website might lead you to believe that the supplement doesn’t contain any chondroitin or glucosamine (or the side effects that come along with them, as with the original Instaflex), this might not actually be the case.

This is because according to WebMD, “Since collagen type II contains chondroitin and glucosamine, large doses might lead to the same side effects as those seen with chondroitin and glucosamine supplements. These side effects include nausea, heartburn, diarrhea and constipation, drowsiness, skin reactions, and headache.”

WebMD recommends taking no more than 2.5mg of collagen type II daily in order to avoid unwanted side effects, although Instaflex Advanced contains 40mg. As such, you’ll definitely want to speak with your physician before taking it.

Now, let’s learn more about the company behind Instaflex Advanced.

Instaflex Advanced’s Manufacturer

As a company, Instaflex, based out of Salt Lake City, UT, had an A+ rating with the Better Business Bureau, based on 62 closed complaints (as of 8/12/15). Most of these appeared to reference problems with the free trial (more about this next).

Per their Terms & Conditions, it appears that Instaflex is also affiliated with Direct Digital LLC, who had a B- rating with the Better Business Bureau, despite only having 6 closed complaints. Again, most of these referenced difficulties with the free trial.

So, what’s all this talk about free trials?

Instaflex Advanced Pricing & Refund Policy

If purchased directly through the company, Instaflex Advanced is only available through an 18-day trial for $4.99 S&H.

Then, after 18 days have passed, you’ll be sent a full bottle (30 capsules) of Instaflex Advanced and charged $69.99 plus $4.99. At this same time, you’ll be enrolled in the company’s autoship program, which means you’ll continue receiving a fresh supply of the supplement once every 30 days, and your credit card will be charged $69.99 plus $4.99 each time.

Note: Instaflex Advanced can also be purchased through several third-party retailers, including GNC, LuckyVitamin.com, and more, which can not only help you save money on S&H charges but can also help you avoid recurring shipments.

Outside of the trial, all Instaflex Advanced purchases come with a 30-day refund policy, less S&H charges. However, keep in mind that if you purchased the supplement outside of the company, your refund policy may vary.

For all direct purchases, you’ll need to contact Instaflex customer service at 800-436-0920 in order to request a refund.

Arbitration

One quick note: All purchases made directly through the company are subject to an arbitration agreement. Basically, this means you’re giving up your right to a trial by jury or becoming part of a class action lawsuit if you experience any damages from using Instaflex Advanced.

Should Instaflex Advanced Be Your First Choice for Joint Pain?

Overall, the only ingredient contained in Instaflex Advanced that has sufficient clinical evidence behind it is boswellia serrata, which you can purchase as a standalone supplement for less than $20 (we even found some priced less than $10) for a full month’s supply, whether online or at your local pharmacy.

On the other hand, Instaflex Advanced comes in at about $2 per capsule. And while you can’t put a price on pain relief (assuming Instaflex Advanced works as advertised), this certainly could be considered steep.

However, as we mentioned at the beginning of this review, what works for you may not work for someone else, depending on the underlying cause of your joint pain.

Considering all of this, we’d strongly recommend speaking with your physician prior to placing your Instaflex Advanced order.


Read 29 Instaflex Advanced Customer Reviews and Complaints

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Average Customer Rating: 2.3
Rating Snapshot:
5 star: 7 4 star: 1 3 star: 2 2 star: 3 1 star:  16
Bottom Line: 28% would recommend it to a friend
Showing 1-11 of 29
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  • 1 out 1 people found this review helpful

    Should have read reviews

    • Oakland Park, FL,
    • Sep 26, 2019
    • Verified Reviewer

    While the first two days my knees improved quickly, I was not prepared for the cramping and diarrhea that began. Each day diarrhea became increasingly worse. Really disappointed because my shellfish allergy limits available product choices.

    Bottom Line: No, I would not recommend this to a friend

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  • 1 out 2 people found this review helpful

    It works for me!

    • California,
    • Sep 25, 2019
    • Verified Reviewer

    September 19, 2019 is my second week of taking Instaflex Advanced. A friend recommended this product as it helped her with arthritis pain. I have lived in 24/7 pain due to Osteoarthritis. I refuse to take prescription medication so I was willing to try anything. I felt better from day one. I have arthritis in my back, hips, pelvic bones and left knee. Walking was very difficult and painful. I took one capsule of Instaflex and 2 extra strength Tylenol in the morning and I was able to walk better with very little pain. I'm about 80% better! This product works for me and I'm very thankful to have found something natural to help me. I got the 14-day free trial to test the product. I'm now on monthly auto-refill. Thank you, Dr. Katz, for creating something that works great!

    Bottom Line: Yes, I would recommend this to a friend

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  • 1 out 2 people found this review helpful

    Really works

    • Gresham, OR,
    • Jul 15, 2019
    • Verified Reviewer

    I usually go in for Cortizone Shots every three months. I’m on my third bottle this month and no shots. These pills work, the knee pain is 75% better and I’m happy for that. Just ordered 5 bottles!

    Bottom Line: Yes, I would recommend this to a friend

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  • 13 out 14 people found this review helpful

    Rip off

    • Brownwood, TX,
    • Mar 13, 2019
    • Verified Reviewer

    This is the most dishonest company around. They talk about fake reviews, stop selling a fake product and misleading people. I paid $4.99 for the sample pack. Don't fall for the $29.95 deal, it's not a bottle, it's just another sample pack. But they call it a travel pack. Biggest rip off ever. Turning them into the Better Business Bureau.

    Bottom Line: No, I would not recommend this to a friend

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  • 17 out 18 people found this review helpful

    Instaflex is a scammer.

    This Instaflex company is a scammer, don't order their drug. Immediately after you order it, they will be removing money from your bank account and mail you a drug you did not order. Secondly, their drug is not good nor working; when I took it I didn't see any improvement at all.

    Bottom Line: No, I would not recommend this to a friend

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  • 33 out 33 people found this review helpful

    Unethical marketing

    • Los Angeles, CA,
    • Jan 18, 2019
    • Verified Reviewer

    I think their marketing procedure is unethical. I never asked for a bottle after I used the trial, which didn't work. I also never received their policy in writing, and never received any emails. They make it very difficult in regard to stopping the program.

    Bottom Line: No, I would not recommend this to a friend

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  • 7 out 9 people found this review helpful

    Seems to be effective.

    • Roswell, GA,
    • Jan 16, 2019
    • Verified Reviewer

    I've been taking Instaflex for about three months...I find it to have helped quite a bit. My knee is arthritic and probably has limited cartilage. I'm trying to hold off knee replacement as long as possible...I have better joint flexibility and less pain.

    Bottom Line: Yes, I would recommend this to a friend

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  • 33 out 33 people found this review helpful

    Don't waste your money!

    • Gulfport, MS,
    • Dec 15, 2018
    • Verified Reviewer

    Don't waste your money. They auto send you more at $75.00 a pop. I wanted to try, and it was shipped. I didn't know it was an autoship. I'm 70, on a fixed income, and $75 is a lot to me. There should be a law against these kinds of scams!

    Bottom Line: No, I would not recommend this to a friend

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  • 28 out 29 people found this review helpful

    They are a rip off, tried to cancel multiple times and they kept charging my credit card, and it didn’t even work!

    • Lake Mary, FL,
    • Dec 9, 2018
    • Verified Reviewer

    I tried multiple times to cancel my subscription, and they kept charging my credit card! Rip off.

    I would not recommend them to anyone. Plus the customer service is terrible! Do not buy or fall for the scam!

    Bottom Line: No, I would not recommend this to a friend

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  • 27 out 27 people found this review helpful

    For knee pain

    • Jacksonville, FL,
    • Nov 17, 2018
    • Verified Reviewer

    After trying many over-the-counter medications for knee pain, I saw this advertisement for Instaflex Advanced and decided to give it a try. I ordered it online from Walgreens, two for one, 14 pills in each bottle. I took it for about 10 days and did notice some relief from pain, however, on the 11th day started to experience severe diarrhea and vomiting, to the point that I had to go to the emergency, and found out that an ingredient in this pill was the problem and caused a bad bacteria infection. So if you are going to take this pill, please check with your primary care doctor to make sure you can take this med. I am not saying it does not work, but everyone should make sure before taking it.

    Bottom Line: No, I would not recommend this to a friend

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  • 39 out 41 people found this review helpful

    Terrible and deceptive marketing

    • Porcupine, SD,
    • Sep 20, 2018
    • Verified Reviewer

    I ordered the free 14-day sample pack and agreed to pay for the shipping. The sample pack never arrived. Then I receive a large bottle in the mail and my account is billed nearly $75.00. I never felt any pain in my joints as I left my living room floor on my way to the ceiling. The only severe pain I felt was a severe and debilitating pain in the pocketbook.

    Bottom Line: No, I would not recommend this to a friend

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