By combining 12 natural, powerful pain relievers and anti-inflammatory ingredients with enzymes, Heal-n-Soothe is a dietary supplement that promises to help promote healing and recovery, reduce muscle discomfort, and support healthy circulation and immune response.
All you have to do is take at least one capsule (up to four times daily, if needed), 30 minutes before or 60 minutes after meals, and the company reports the supplement’s ‘systemic enzyme therapy’ could begin delivering results.
But is Heal-n-Soothe really "Mother Nature's feel-good formula,” as advertised on the website? Does it actually contain ingredients that have been clinically proven to work? We’ll explore important questions like these in this article, starting with the topic of enzymes.
What Is Systemic Enzyme Therapy & Is It Effective?
While we didn’t encounter much detailed information about systemic enzyme therapy during our research, writing for Science-Based Medicine, Scott Savura defines it as consuming enzymes orally “with the intent of whole-body effects."
Specifically, the therapeutic approach is often promoted as a way to address inflammation, which Scott reports is a “host of complex physiologic processes mediated by the immune system,” often expressed as redness, heat, pain, and swelling.
From a clinical perspective, he points out that enzyme therapy “can be science-based,” since it’s often used to treat pancreatic disease and cystic fibrosis, but he tempers this by emphasizing that “those are not uses where the enzymes need to be absorbed from the gastrointestinal tract,” since they’re often injected in very large doses.
Comparatively, “the concept of giving enzymes orally, and achieve meaningful therapeutic effects in the body, is one with a considerable number of drug design hurdles,” he says. As a result, “until better evidence appears to demonstrate the efficacy and safety of systemic enzyme therapy,” he emphasizes, “their use can’t be considered science-based.”
With this core information in mind, which enzymes will Heal-n-Soothe’s formula deliver, and what does the clinical evidence have to say about their efficacy?
Taking a Closer Look at Heal-n-Soothe’s Ingredients
According to the supplement facts label listed on their website, Heal-n-Soothe contains the following ingredients:
- Boswellia Extract 150 mg
- Citrus Bioflavonoids 90 mg
- Ginger Extract 90 mg
- Mojave Yucca (root) 90 mg
- Turmeric 60 mg
- Alpha Lipoic Acid 50 mg
- Rutin 30 mg
- Devil’s Claw Extract 30 mg
- Systemic Enzyme Blend 7540 mg: Protease AM 225 AP, Bromelain 6M FCCPU, Protease 6.0 60,000 HUT, Alkaline Protease 12,000 USP, Papain 1.5M FCCPU
Before diving in, it’s important to point out that the HighYa team doesn’t have a scientific background when it comes to the biological effects of dietary supplements. This means that when reporting on whether or not an ingredient is effective for a specific claim, we rely on the cumulative clinical evidence reported by sites like the Natural Medicines Database, Examine.com, and WebMD.
According to these sites, some studies indicate that taking 100-333 mg of certain Indian frankincense (Boswellia serrata) extracts daily can improve joint pain and mobility by anywhere between 32 and 65 percent in those with osteoarthritis.
Similarly, taking between 250 and 500 mg of ginger extract, three to four times daily, has been shown in some studies to reduce arthritis-related hip and knee pain, as well as standing and walking pain and stiffness in those with osteoarthritis. In some instances, it worked about as well as 400 mg of ibuprofen, while in others it did not.
500 mg of turmeric (which contains an active chemical called curcumin), when taken two to four times daily for two to six month, has been shown to reduce pain and improve function in people with osteoarthritis. In some instances, it reduced pain as much as ibuprofen, but didn’t reduce inflammation as much as the drug diclofenac.
Rutin, whether contained in Heal-n-Soothe or another dietary supplement, is a type of plant pigment (flavonoid) that might have antioxidant and anti-inflammatory effects. And when combined with 288 mg of trypsin and 540 mg of bromelain, taking 600 mg per day has been shown to “be about as effective as the medication diclofenac (Voltaren) in relieving pain and improving knee function in people with osteoarthritis.”
Another potentially helpful ingredient related to osteoarthritis is devil’s claw. In some studies, taking between 400 mg and 2.6 grams per day for between two and four months has been shown to help decrease pain, often in the hip and knee.
Finally, while we learned earlier that a combination of rutin and bromelain might have some osteoarthritis-related benefits, these same sites didn’t indicate that it—or any of the remaining enzymes or ingredients found in Heal-n-soothe—will deliver on the manufacturer’s claims.
Potential Side Effects Related to Heal-n-Soothe’s Ingredients
The disclaimer at the bottom of Heal-n-Soothe’s website emphasizes that some of these ingredients could thin blood, and that the supplement shouldn’t be taken by anyone who’s allergic to pineapple or papaya, or by those who are pregnant or nursing.
They also note that it’s possible to experience side effects (no dosages or other circumstances noted) like sinus drainage, gas or loosening of the stool, and decreased blood pressure.
WebMD and the Natural Medicines Database report that in some instances (again, no dosages or other circumstances provided) turmeric can cause stomach upset, nausea, dizziness, or diarrhea.
They also tell us that while devil’s claw is possibly safe when used for up to one year and that the most common side effect is diarrhea, “other possible side effects include nausea, vomiting, stomach pain, headaches, ringing in the ears, loss of appetite, loss of taste,” and allergic skin reactions.
How Much Does Heal-n-Soothe Cost?
Heal-n-Soothe is only available directly from the manufacturer, through the following two options:
- One-Time Order (90 vegetarian capsules): $59
- Free Trial: $9.95 S&H
If you choose the trial option, you’ll be billed the full price of $49.95 after 14 days have passed, and will continue receiving a new bottle each month and paying $49.95 each time, until you cancel.
Living Well Nutraceuticals offers a 90-day refund policy on all Heal-n-Soothe orders, less S&H, which you can request by calling (888) 231-9901 or sending an email to email@example.com.
Are There Any Online Heal-n-Soothe Customer Reviews?
Heal-and-Soothe was previously available through Amazon, where more than 50 customers had given the supplement an average rating of 3.5 stars. Common compliments revolved around reduced pain and inflammation, while complaints often referenced no results, difficulty obtaining a refund, and side effects like digestive upset.
As far as the company, Heal-n-Soothe is distributed by Living Well Nutraceuticals, based out of Glendale, CA. They weren’t listed with the Better Business Bureau as of 2/21/18, although the company manufactures several other dietary supplements, including Rub on Relief natural pain cream, SleepZyme sleep aid, and ThinMist weight loss spray.
Heal-n-Soothe vs. Other Systemic Enzyme Therapy Supplements
Browsing online marketplaces like Amazon and Google Shopping, we encountered several popular enzyme supplements competing with Heal-n-Soothe:
|Supplement||Price||Active Enzyme(s)||Other Ingredients?|
|Heal-n-Soothe||$49 - $59||Bromelain, Papain||Boswellia, bioflavonoids, ginger, yucca, turmeric, ALA, rutin, devil's claw|
|NOW Super Enzymes||$11+||Bromelain, Ox Bile, Pancreatin, Papain||No|
|Doctor’s Best Proteolytic Enzymes||$21||Bromelain, Papain, Amylase, Lipase, Serratiopeptidase, Lipase||Neutral, fungal, and bacterial protease, rutin|
|Enzymedica Repair Gold||$30+||Bromelain, Amylase, Catalase, Papain, Serratiopeptidase, Lipase||No|
|Source Naturals Daily Essential Enzymes||$42||Pancreatin, Acid-Stable Protease, Lipase, Amylase, Amyloglucosidase, Cellulase, Lactase||No|
|Wobenzym N||$25+||Pancreatin, Papain, Bromelain, Trypsin, Chymotrypsin, Rutoside||No|
Given all these options, formulations, and price points, what’s the best way to figure out which one—if any—is right for you?
As we always emphasize, start by talking with your doctor. They can help diagnose the underlying cause of your pain, discomfort, and inflammation, and then recommend a science-based treatment from there.
If they recommend pursuing a dietary supplement, after writing about hundreds of different formulations over the years, we’d recommend only doing business with manufacturers who:
- List all of their ingredients, including dosages, with no proprietary blends (which don’t list dosages)
- Support their claims with quality clinical evidence
- Back their products with at least 30-day refund policies and don’t charge restocking fees
Does this mean you should do business with Living Well Nutraceuticals and place an order for Heal-n-Soothe?
Our Final Thoughts About Heal-n-Soothe
Pain is a complex process, and it will take the help of a physician to narrow down what’s causing yours, and then prescribe a viable treatment. So—again—whether you're considering Heal-n-Soothe or another dietary supplement, they're perhaps your best resource for achieving the most bang-for-your-buck.
With this in mind, based on what we learned earlier, while systemic enzyme therapy as a whole might not seem to have much clinical support, several of Heal-n-Soothe’s individual ingredients are reported by sites like Examine.com and WebMD to be possibly effective for osteoarthritis-related benefits. Which could be positive, as long as this is the cause of your pain. If not, you might be flushing your money down the drain.
Pro tip: However, many of these ingredients (ginger, turmeric, rutin, and devil’s claw) aren’t found in the same dosages in Heal-n-Soothe as referenced in supporting clinical trials.
Even when referencing the same source of pain, the reality is that everyone’s body is different, so what works for one patient might be a total fail for another. For this reason, it’s positive that Living Well Nutraceuticals seems to stand behind Heal-n-Soothe with a 90-day refund policy—just keep in mind that you’ll have to pay to send the bottle back if you’re dissatisfied.
16 out 18 people found this review helpful
Very positive results from Heal-n-Soothe
I developed knee joint pain and aggravated osteoarthritis of my big toe after being prescribed Anastrozole (hormone inhibitor). I was not able to play pickleball without putting braces on my knees, couldn't get into some shoes due to swelling of the big toe, and couldn't walk beyond 2 miles versus the typical 5.5 - 6.5 miles I did regularly prior to the Anastrozole. I actually had surgery planned to address the pain in Stage 4 Rigid osteoarthritis.
I started Heal-n-Soothe and noticed a difference by day 4. Ten days later I canceled the surgery on my big toe. I have been taking Heal-n-Soothe for 3 months now with no pain. I play pickleball approximately 3 - 5 hours a day, 3 times a week, and walk 6.5 miles once a week. I recommended it to several friends and 3 of the 4 have experienced the same reduction in pain as I experienced.
Bottom Line: Yes, I would recommend this to a friend
13 out 14 people found this review helpful
I don't know how to put this, but you know how you have to stop taking one supplement to see if the other supplement is pulling its own weight? Well, I combined Heal-n-Soothe with Extreme Joint Care by NutraBio and within 8-13 days, I don't know exactly because I bent down for some reason yesterday and my left knee didn't hurt after 18 months or so of pain. So I squatted 5 more times, no pain, just creeking. Well, if I am on a good run, why stop now? So these two manufacturers might be expecting another visit from me jointly, which I'm sure they too are with that old sayin,' whatever works.
Bottom Line: Yes, I would recommend this to a friend
15 out 21 people found this review helpful
Itching and hoarseness
I was extremely excited by the rapid improvement in my knees. I had become embarrassed to get up when I was teaching in front of my students due to the grunts and groans and limitations in movement. After a week or two on Hea-n-Soothe my knees felt like had cushions and overall flexibility and movement was easier; specifically getting up and down to reach or perform minor household tasks.
Then I realized that I was hoarse on a daily basis. I'm a professional singer and voice teacher, so this was a serious issue. I also read on some sight that papain, the papaya enzyme can actually cause throat damage, a very serious concern given my work, not to mention that it was annoying.
Also, I started having itching throughout my body, including my hand, just little annoying tings, irritating at night especially. After discontinuing, I continue to have this side effect, though diminished.
I still recommend the product to my friends because I considered the positive aspect miraculous, especially because I thinking knee replacements would be in my future.
The company has been pretty responsive as I've asked for advice on these side effect issues and ultimately sent me a dietary book which supposedly has similar results over a longer period of time.
A friend also told me that papain has been banned in surgical procedures because it could lead to major heart problems, another good reason to be wary, yet given my very positive results, I still tell my friends.
I am, however, seeking other supplements and would like to find a medically trained professional for advice; perhaps online info will suffice. It's not fun have major movement restrictions, so I'm highly motivated.
Bottom Line: Yes, I would recommend this to a friendView all 1 commentsHide comments
Sep 23, 2018
I don't understand this guy, he would state how well this product helped his pain in his knee, then comment's on how the ingredient caused severe hoarseness and discovered that this ingredient caused heart problems that were banned by doctor's, but this guy continued to recommend this to his friends! What? Is this guy for real, or is this just a made up story? Or what?
40 out 42 people found this review helpful
Be very careful not to become auto enrolled
The product ingredients are similar to other arthritis products that are sold at lower prices directly or through Amazon. The online sales pitch for Heal-n-Soothe is so enticing that is SO EASY TO MISS the AUTO ENROLL that appears only on the "Get another bottle for $10" window. They do not provide return shipping or return labels and Iris from customer service told me "many other companies have similar fine print so customers don't see the enrollment they have agreed to." While the placebo effect left me feeling like the product did not hurt me, returning unwanted bottles of something that was not helping me left a bad enough taste for me to write this negative review.
Bottom Line: No, I would not recommend this to a friend
18 out 18 people found this review helpful
I began taking Heal-n-Soothe as suggested. I began with one capsule in the morning and one in the afternoon.
I got a nosebleed the second day and for two subsequent days. I have never experienced spontaneous nosebleeds before. I stopped taking the product because it was the only change in my diet. The nosebleeds stopped.
I tried again two weeks later with the same results. I don't have enough pillowcases to continue with it.
Next miracle pain cure anyone?
Bottom Line: No, I would not recommend this to a friend
63 out 67 people found this review helpful
90-day money back guarantee - yeah, right!
This isn't as much a review of Heal-n-Soothe as a complaint about the company I ordered it from, The Healthy Back Institute. I also ordered their product called Super Joint Support not knowing that it had Magnesium in it (the type of Magnesium not identified). I know from experience and advice that the only type of Magnesium that does not cause diarrhea is Magnesium Glycinate (which I already take to stop muscle cramps). So I wasn't at all surprised that by the second day of taking Heal-N-Soothe, sure enough, I was "trotting to the pot!"
I called the company to ask the type of magnesium and they couldn't tell me, so I returned the Super Joint Support, giving the reason, and paying $10.92 for return it by USPS. After not receiving a refund, I called the company and was told I'd returned Heal-N-Soothe (the first bottle had cost me $29, while the Super Joint Support had cost me $39).
I wrote a letter to the company enclosing the Return Form and telling them I would expose them on social media if I didn't get a refund! Still no refund! So it cost me a total of $49.92 for this experience! Whether Heal-N-Soothe works or not, it's hard to tell when I'm so mad at the company for being so dishonest!
Oh, but the last time I had my blood pressure checked, it was low, but I'm surprised it wasn't "through the roof!" I was actually looking up something on WebMD when I got sucked in by this company, so watch out! Oh, and I forgot to mention all the newsletters at $14.95 a copy!
Bottom Line: No, I would not recommend this to a friendView all 1 commentsHide comments
Jun 13, 2018
Well, you've cured me!
18 out 19 people found this review helpful
Does not work! Another snake oil by a traveling sell man. Just another scam. It is a shame when people like me are in pain.
Bottom Line: No, I would not recommend this to a friend