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Unify Health Labs Multi-GI 5

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164 Customer Reviews

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Unify Health Labs claims to offer a dietary supplement that will support healthy digestive to improve whole-body health. This product may be able to offer a reasonable option for digestive, immune, and overall health. However, the dosages contained in this dietary supplement are much lower when compared to clinical studies.


  • Prebiotics and probiotics blends are generally recognized as safe (GRAS)
  • Blend of ingredients and their strains all relate to promoting gut microbiota
  • 90-day money-back guarantee


  • Certain strains can provide side effects that may include diarrhea, cramping, flatulence, and constipation
  • Longer than normal shipment, taking as long as 15-20 days

Unify Health Labs Multi-GI 5 Review: Is It Safe and Effective?

By Rocklend Davis, Ph. D.

Updated on: Jul 13, 2020

What Is Multi-GI 5

Multi-GI 5 is a dietary supplement from Unify Health Labs that contains prebiotics, probiotics, and a blend of ingredients alleged to improve gut health.

In your gastrointestinal tract (GI), prebiotics allows for changes in the composition and/or activity of microorganisms to occur in the GI tract.

Probiotics help to develop the microorganisms in the GI to help ensure an appropriate balance of the bacteria that is necessary to maintain normal function in the GI.

Specifically, improved digestion is associated with more efficient absorption of important nutrients that we get from a well-balanced diet.

Unify Health Labs claims that you will experience benefits with daily use of their dietary supplement. According to their website, by taking 1 scoop, the company alleges that you may experience:

  • Healthy digestion
  • Improved weight management
  • Increased energy
  • Healthy GI lining
  • Balanced gut flora

In this article, we’ll help you determine if there is in fact support to back the claims made by Unify Health Labs by reviewing available research for the active ingredients.

Multi-GI 5 Ingredients: Do They Work?

Multi-GI 5 contains 3 blends of ingredients to support gut health: GI Health Blend, Prebiotics, and Probiotics. It is easy to see that the proposed benefits of this supplement are related to this blend of prebiotic and probiotic strains.

First, we’ll discuss GI Health Blend ingredients.

Fermented L-Glutamine, 200 mg

Glutamine is an amino acid in the human body and is primarily used by the cells in the intestinal wall.

While there appears to be some progress made with glutamine supplementation in the role of GI health, most of the progress is based on observational studies.

Acute oral glutamine supplementation, even at lower dosages (0.25 g kg), was able to support GI health in a study of healthy active males.

Magnesium BHB (KetoVantage ®), 70 mg

Beta-Hydroxybutyrate (BHB) is a ketone body that is used by the brain as fuel. Further, BHB may aid in transporting energy from the liver to the surrounding tissues while fasting or during exercise.

Results from a study of healthy trained cyclists found that BHB supplementation increased exercise performance by 2%.

Studies, however, are limited with regards to understanding BHB supplementation and performance of higher intensity exercise. A study of trained endurance athletes experienced a decrease in endurance at a higher intensity. This effect may be present due to decreased representation of carbohydrates.

Deglycyrrhizinated Licorice Root Extract, 50 mg

Deglycyrrhizinated licorice (DGL) extract had the glycyrrhizin removed. Due to the removal of this compound may limit or even decrease adverse effects in its true form licorice.

A laboratory study found that deglycyrrhizinated licorice may play a role in alleviating ulcers from aspirin-induced mucosal damage in rats.

DGL extract of 75 mg, taken twice daily was used to treat functional dyspepsia and was revealed to improve symptoms in humans. The DGL dosage contained in this GI Health Blend, according to the nutrition label on Unify Health Labs, indicates 50 mg.

BioPerine ® Piper Nigrum Extract, 10 mg

Piper Nigrum Extract, also known as black pepper, may be used for medicinal purposes or as a preservative. Dietary piperine plays a role in stimulating the digestive enzymes of the pancreas, enhances the digestive capacity, and decreases GI food transit time.

However, these health benefits are only shown in animal studies. Further studies and research are required in humans to confirm effects, especially in the long-term.

BioPerine received a GRAS status (generally recognized as safe).

Berberine Hydrochloride, 3 mg

Berberine is known as an alkaloid that comes from plants. Berberine may have a role in anti-diarrhea and anti-inflammatory.

A study of 196 patients with irritable bowel syndrome received berberine hydrochloride of 400 mg twice daily for 8 weeks. The findings from the study suggest that berberine hydrochloride can reduce GI issues.

Further, berberine hydrochloride supplementation at this dosage presented with side effects that were related to digestion. Some reports included:

  • Cramping
  • Diarrhea
  • Flatulence
  • Constipation
  • Stomach pain

These symptoms disappeared after decreasing the dosage by 300 mg. Included in one scoop of the Multi-GI 5 GI Health blend is 3 mg of berberine hydrochloride, which is well under the dosage utilized in the study.

Nonetheless, if you begin to notice any of the side effects, stop taking the supplement.

Zinc (from Zinc Carnosine Complex), 1 mg

Zinc is an essential trace element and is involved in numerous life processes. Zinc can be found in meats, dairy, nuts, grains, and beans. Zinc may also play a role in strengthening the integrity of the gut.

In mice, zinc was found to impact gut microbiota and offer protection to conditions affecting digestive health. Also, the effects of zinc and their role for gut health in humans needs to be further research.

Prebiotic Blend

Fructooligosaccharide (FOS) 4 g

Oligosaccharides occur naturally and can be found in plants such as onions, chicory, garlic, asparagus, banana, artichoke, and many others.

This blend helps to feed the intestinal gut microbes and the by-product that is released into the blood helps the gastrointestinal tracts.

Low quantities of fructooligosaccharides exist in food.

Prebiotics help regulate the environment of gut microbes in humans. The gut microbes or microbiota are considered its separate organ that contains a large number of bacterial cells that will help to perform many functions.

Further, the use of prebiotics to treat and influence gut health are strain-dependent. A review of 43 studies to examine the effectiveness of prebiotics to treat irritable bowel syndrome (IBS) and constipation were inconclusive. This may be due to the limited studies available of prebiotics in humans.

Probiotic Blend

This blend of probiotic contains 5 strains of good bacteria to improve digestion, weight management, and reduce gas and bloating.

Lactobacillus gasseri (100 billion cfu/g) 9 mg

This particular probiotic helps to support immune systems and colonizes approximately 40% of your digestive tract. Also, it may help to help lower stress levels in patients suffering from irritable bowel syndrome (IBS) by improving gut microbiota in healthy adults, improve mental state, and sleep quality.

ProDura ® Bacillus coagulans (150 billion cfu/g) 7.26 mg

Bacillus coagulans is a lactic acid that produces spore-forming bacterial species. This formation protects B. coagulans as it travels through the acidic environment of the stomach to reach the intestines. Once it has reached its destination, it begins the process of germination that will aid in the digestion of carbohydrates and proteins.

B. coagulans may also contribute to increased benefits of prebiotics by encouraging the growth of more healthy gut bacteria. A study supplemented B. coagulans for 28 days in elderly subjects was found to have influenced a higher density of healthy gut bacteria.

A review of toxicology testing studies has found that Bacillus coagulans have a history of safety for human consumption.

Lactobacillus rhamnosus (350 billion cfu/g) 7.13 mg

L. rhamnosus is a commonly used strain and appears to be well documented for the prevention and treatment of infections that occur in the gastrointestinal tract. Furthermore, it may play a role in the treatment and prevention of diarrhea and prevent allergic reactions.

A meta-analysis of 12 randomized control studies suggests that Lactobacillus rhamnosus has a role in preventing antibiotic-associated diarrhea in adults who were treated with antibiotics.

A clinical trial was also able to show the ability of this probiotics role in modulating the gut microbiota composition. This eventually leads to a decrease in potentially harmful bacteria and supports the good bacteria.

Lactobacillus plantarum (400 billion cfu/g) 3 mg

These are identified as good bacteria that attack the bad bacteria.

The possible benefits of L. plantarum may include reducing toxins, bloody pressure, fungal activity, and symptoms of irritable bowel syndrome (IBS).

In a clinical trial, L. plantarum was able to decrease symptoms of IBS, particularly the symptoms of abdominal pain and bloating.

While there were no known side effects while taking L. plantarum, there was only one report of an adverse event by transient vertigo in one of the subjects in the trial.

Lactobacillus Casei (300 billion cfu/g) 7.13 mg

Lactobacillus Casei is reported to stimulate the production of lactic acid to help aid in healthy digestion, nutrient absorption, and regularity (gas and bloating).

In a study of 70 patients with constipation were randomized to consume 65 mL of L. casei and noted significant improvement of self-reported symptoms when compared to the control.

Is Multi-GI 5 Safe?

According to the nutrition label found on Unify Health Labs’ website, one scoop contains the 3 blends and is instructed to take twice daily.

The available blends contain ingredients that are associated with side effects that include diarrhea, cramping, flatulence, and constipation. If you do begin to experience these symptoms, stop taking the supplement, and notify your physician immediately.

The dosages of the ingredients are well under the dosages that were used in the studies. Lower dosages combined with natural ingredients provide a favorable safety profile.

It is recommended to take the dietary supplement as indicated on Unify Health Lab’s Website. Dosing of any amount should never be increased.

The Cost

Multi-GI 5 is available on Unify Health Labs website. There are multiple purchasing options and ships to you in 15-20 business days. One container of Multi-GI 5 contains 30 servings.

  • 1 bottle (1 month supply) - $69.95
  • 3 bottles - $188.85 (savings of $21.00)
  • 6 bottles - $353.70 ( savings of $66.00)

Each order is backed by a 90-day money-back guarantee with no hassle. To process your refund, email support@unifyhealthlabs.com or call 800-935-4598.

The Bottom Line

Multi-GI 5 includes 3 blends of ingredients that offer many scientifically proven benefits. As a comprehensive blend with many ingredients, this supplement may support overall gut health.

While the dosing of each ingredient is included and safe, it may be too little to achieve the proposed benefits.

We have reviewed products that seek to promote gut health with comprehensive blends and are similarly priced. You may save by avoiding the need for additional supplements, however.

Before treating symptoms on your own, speak with your doctor first.

Customer Reviews

4.0 Stars out of 164 Reviews
5 Star:41% 4 Star:40% 3 Star:6% 2 Star:4% 1 Star:7%
81% Recommend This Product
Start your review of Unify Health Labs Multi-GI 5:
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Posted on May 18, 2022

Still early, but so far so good!

By Patricia W., Louisiana, Verified Reviewer

I have been experiencing retching and vomiting for years now, but only when I’m having a BM. These episodes only use to happen 2–3 times a month, or less, but lately much more often. Doctors have been no help. I’ve only been using Multi-GI 5 for three weeks, but I’ve not had an episode of what I described since. Only time will tell, so I’ll continue to drink the Multi-GI 5 to see if it’s really helping. It tastes really good, especially when blended with Crystal Light Wild Strawberry drink. I put 8 oz in a blender, add one or two ice cubes — delicious!

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

Taste good

Easy to prepare


Too early to honestly say whether it’s helping or not

Having to prepare it

The cost

Posted on May 18, 2022

Great product

By Sonya K., Atlanta, GA, Verified Reviewer

My daughter and I have been using the product for about a month and it has changed her life! She has IBS and has had a stomach ache daily for a long long period of time. After eating she would throw up her food. I am glad to say she has stopped having stomach aches and no longer is throwing up after eating! I wish we had known about GI-5 long ago! Thank you for giving my daughter a better quality of life. I am also feeling better as well.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Great taste

Works great

Works quickly

Wish it would break down better in liquid

It would be great if it was pill or liquid form


Posted on May 18, 2022

Great product!

By Michelle K., Canada, Verified Reviewer

I had noticed right away in the first week that I had started to lose pounds. I’ve been taking it for a month and a half and have lost 17 lbs so far!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

The results

The flavor

The easiness of taking it

No “cons” were specified in this review

Posted on May 17, 2022

I love it

By Sarah M., Maricopa, AZ, Verified Reviewer

I love the taste in water or my favorite juice. I can already see a difference in my belly. I’m so satisfied with this product, I’m going to buy more and give some to my daughter. I’ve told my friends and family about Multi-Gl 5 and how great it makes me feel. This is one I’ll keep for life. Thank you for making such a difference in my life, I love you Randy.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

The taste

How good I feel

And how great I look

I wish there was more in the container

I wish I could afford to get a bundle

Posted on May 17, 2022

Easiest weight loss ever!

By Tracey W., Holiday, FL, Verified Reviewer

I started using Multi-GI 5 about 2 weeks before having my gallbladder removed. I wanted to try and get some weight off before surgery, plus the MRI I had done showed I had mild fatty liver. When listening to the presentation, it sounded almost too easy, and exactly what I needed, but from seeing Randy Jackson on TV for so many years, it felt personal. And there's NO doubt that he had obviously dropped a lot of weight. So I decided to give it a try.

In the 3 weeks prior to surgery, I dropped 18 lbs. I was elated. I was a little surprised by the heat note in the drink, as it was supposed to be strawberry lemonade flavor (which it definitely is), but it made me think, well, that's what's gonna burn that fat away! I have become almost addicted to that heat now, and look forward to my drink every day. After surgery, now 1 week ago, I am down another 5 lbs. I had gained some weight back after surgery, but quickly came off once I resumed the Multi-GI 5, and not even through my first jar, but almost. I could not be happier!

I still can't even really do normal activity like before my surgery, and STILL the weight is coming off, with also a total loss of 8 inches, mostly in the waist. Would recommend to everyone!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Easy to use

Love the taste

Fast, easy weight loss

No “cons” were specified in this review

Posted on May 17, 2022

You gotta try Multi-GI 5

By Marion M., Bronx, NY, Verified Reviewer

My overall experience with Multi-GI 5 has been a good experience. I just started using Multi-GI 5, I hope to have a better experience as I continue using the product. I will be ordering my second jar. Thank you.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Helps with digestion

Helps with bowel movement

I notice my stomach is getting smaller

I don’t like the taste, it’s too sweet

Posted on May 16, 2022

Day 1

By Jodi W., Albany, NY, Verified Reviewer

Just received my order of GI 5. So excited. Already took my first serving. The taste was good. A little hard to mix but oh well. I’m still going to take it.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons


Quick delivery

Hard to mix

Posted on May 15, 2022

It can't hurt. It might help.

By Rene H., Brandenburg, KY, Verified Reviewer

When I first opened the container, there was a fine powder that escaped into the air that made me cough. I figured it was due to shipping, but no. I dread opening the container every day because of the fine powder that escapes into the air that causes me to cough. A capsule version would be nice.

Taste? I tried it first on its own with water. It left an aftertaste, so now I mix it in juice or my protein shake.

Effects? I truly haven't noticed any changes or improvements in my gut. I eat healthy because I have IBS and gastroparesis. I have a BMI of 27 with most of my fat being in my gut. I'm literally willing to try anything to help my gut get healthier. I've been using this product every day for about 3 weeks. I'm hoping that the longer I use it, the better my gut issues will get. I'm also hoping for more energy.

I'm 51 years old so I'm not expecting a one-dose miracle. It took time for my gut issues to develop. It will take time for something to help. My recommendation today is I don't think it can make my stomach worse and it might make it better with more time.

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

Multiple ingredients that have been linked to support gut health

Shipment was quick

It's a fine powder that gets into the air, no matter how slow my movements, that makes me cough

Aftertaste when taken with plain water

Bait game at checkout where other offers are made for discounts, this seems scammy to me, just offer 1 reasonably-priced item

Posted on May 4, 2022

I approve!

By Janie W., Wellington, CO, Verified Reviewer

I have been using this product for less than a month, but it definitely helps keep me regular. I have struggled with my gut for years and finally found something that makes me feel good inside. I have tried multiple things to try to stay regular, and most failed or were super harsh on my stomach/GI tract. Since I have tried Multi-GI 5, not only do I feel better but it tastes good!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

It works

It tastes good

Easy to use

No “cons” were specified in this review

Posted on May 4, 2022

I love Unify Health Labs Multi-Gi 5

By Pamela S., Fort Lauderdale, FL, Verified Reviewer

I must admit that I was wondering, with skepticism, about taking this product. I ordered enough for my son and I both to try it as neither of us was having bowel movements except for every 4–5 days. That was both of our concerns as we knew this was unhealthy and we were miserable!

After the 1st day's use, by that night, we began to expel gas. By the next afternoon, each of us was able to have a bowel movement! Hurray! We continued to use it daily and have movements regularly! Plus, I have lost 3 lbs. Nothing has helped me lose any weight. In fact, I saw my Primary Care Physician today, and I have lost another pound!

We will continue with your product and are both looking forward to what else this will do!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Regular bowel movements

Weight loss

The taste is fantastic

It is pricey

No matter what, it causes us to cough and choke when opening the container

Posted on Apr 23, 2022

I like this product

By Mary Anne H., Ocean Pines, MD, Verified Reviewer

I was interested in boosting my GI health and synchronisticly came across this product. I'm overdue for some weight loss too.

A few weeks ago I began drinking Multi-GI 5. It's easy to stay on track because it's light and good flavored. Without any other effort, I've been eating less and healthier.

My system is functioning very well. I'm pleased with the product and am looking forward to starting the liver cleanse soon. I've been taking the vitamins as well.

Thanks Randy.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons



Powder goes up my nose scooping it out of container

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