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Unify Health Labs Multi-GI 5

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Unify Health Labs Multi-GI 5

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86 Customer Reviews

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Unify Health Labs claims to offer a dietary supplement that will support healthy digestive to improve whole-body health. This product may be able to offer a reasonable option for digestive, immune, and overall health. However, the dosages contained in this dietary supplement are much lower when compared to clinical studies.


  • Prebiotics and probiotics blends are generally recognized as safe (GRAS)
  • Blend of ingredients and their strains all relate to promoting gut microbiota
  • 90-day money-back guarantee


  • Certain strains can provide side effects that may include diarrhea, cramping, flatulence, and constipation
  • Longer than normal shipment, taking as long as 15-20 days

Unify Health Labs Multi-GI 5 Review: Is It Safe and Effective?

By Rocklend Davis, Ph. D.

Updated on: Jul 13, 2020

What Is Multi-GI 5

Multi-GI 5 is a dietary supplement from Unify Health Labs that contains prebiotics, probiotics, and a blend of ingredients alleged to improve gut health.

In your gastrointestinal tract (GI), prebiotics allows for changes in the composition and/or activity of microorganisms to occur in the GI tract.

Probiotics help to develop the microorganisms in the GI to help ensure an appropriate balance of the bacteria that is necessary to maintain normal function in the GI.

Specifically, improved digestion is associated with more efficient absorption of important nutrients that we get from a well-balanced diet.

Unify Health Labs claims that you will experience benefits with daily use of their dietary supplement. According to their website, by taking 1 scoop, the company alleges that you may experience:

  • Healthy digestion
  • Improved weight management
  • Increased energy
  • Healthy GI lining
  • Balanced gut flora

In this article, we’ll help you determine if there is in fact support to back the claims made by Unify Health Labs by reviewing available research for the active ingredients.

Multi-GI 5 Ingredients: Do They Work?

Multi-GI 5 contains 3 blends of ingredients to support gut health: GI Health Blend, Prebiotics, and Probiotics. It is easy to see that the proposed benefits of this supplement are related to this blend of prebiotic and probiotic strains.

First, we’ll discuss GI Health Blend ingredients.

Fermented L-Glutamine, 200 mg

Glutamine is an amino acid in the human body and is primarily used by the cells in the intestinal wall.

While there appears to be some progress made with glutamine supplementation in the role of GI health, most of the progress is based on observational studies.

Acute oral glutamine supplementation, even at lower dosages (0.25 g kg), was able to support GI health in a study of healthy active males.

Magnesium BHB (KetoVantage ®), 70 mg

Beta-Hydroxybutyrate (BHB) is a ketone body that is used by the brain as fuel. Further, BHB may aid in transporting energy from the liver to the surrounding tissues while fasting or during exercise.

Results from a study of healthy trained cyclists found that BHB supplementation increased exercise performance by 2%.

Studies, however, are limited with regards to understanding BHB supplementation and performance of higher intensity exercise. A study of trained endurance athletes experienced a decrease in endurance at a higher intensity. This effect may be present due to decreased representation of carbohydrates.

Deglycyrrhizinated Licorice Root Extract, 50 mg

Deglycyrrhizinated licorice (DGL) extract had the glycyrrhizin removed. Due to the removal of this compound may limit or even decrease adverse effects in its true form licorice.

A laboratory study found that deglycyrrhizinated licorice may play a role in alleviating ulcers from aspirin-induced mucosal damage in rats.

DGL extract of 75 mg, taken twice daily was used to treat functional dyspepsia and was revealed to improve symptoms in humans. The DGL dosage contained in this GI Health Blend, according to the nutrition label on Unify Health Labs, indicates 50 mg.

BioPerine ® Piper Nigrum Extract, 10 mg

Piper Nigrum Extract, also known as black pepper, may be used for medicinal purposes or as a preservative. Dietary piperine plays a role in stimulating the digestive enzymes of the pancreas, enhances the digestive capacity, and decreases GI food transit time.

However, these health benefits are only shown in animal studies. Further studies and research are required in humans to confirm effects, especially in the long-term.

BioPerine received a GRAS status (generally recognized as safe).

Berberine Hydrochloride, 3 mg

Berberine is known as an alkaloid that comes from plants. Berberine may have a role in anti-diarrhea and anti-inflammatory.

A study of 196 patients with irritable bowel syndrome received berberine hydrochloride of 400 mg twice daily for 8 weeks. The findings from the study suggest that berberine hydrochloride can reduce GI issues.

Further, berberine hydrochloride supplementation at this dosage presented with side effects that were related to digestion. Some reports included:

  • Cramping
  • Diarrhea
  • Flatulence
  • Constipation
  • Stomach pain

These symptoms disappeared after decreasing the dosage by 300 mg. Included in one scoop of the Multi-GI 5 GI Health blend is 3 mg of berberine hydrochloride, which is well under the dosage utilized in the study.

Nonetheless, if you begin to notice any of the side effects, stop taking the supplement.

Zinc (from Zinc Carnosine Complex), 1 mg

Zinc is an essential trace element and is involved in numerous life processes. Zinc can be found in meats, dairy, nuts, grains, and beans. Zinc may also play a role in strengthening the integrity of the gut.

In mice, zinc was found to impact gut microbiota and offer protection to conditions affecting digestive health. Also, the effects of zinc and their role for gut health in humans needs to be further research.

Prebiotic Blend

Fructooligosaccharide (FOS) 4 g

Oligosaccharides occur naturally and can be found in plants such as onions, chicory, garlic, asparagus, banana, artichoke, and many others.

This blend helps to feed the intestinal gut microbes and the by-product that is released into the blood helps the gastrointestinal tracts.

Low quantities of fructooligosaccharides exist in food.

Prebiotics help regulate the environment of gut microbes in humans. The gut microbes or microbiota are considered its separate organ that contains a large number of bacterial cells that will help to perform many functions.

Further, the use of prebiotics to treat and influence gut health are strain-dependent. A review of 43 studies to examine the effectiveness of prebiotics to treat irritable bowel syndrome (IBS) and constipation were inconclusive. This may be due to the limited studies available of prebiotics in humans.

Probiotic Blend

This blend of probiotic contains 5 strains of good bacteria to improve digestion, weight management, and reduce gas and bloating.

Lactobacillus gasseri (100 billion cfu/g) 9 mg

This particular probiotic helps to support immune systems and colonizes approximately 40% of your digestive tract. Also, it may help to help lower stress levels in patients suffering from irritable bowel syndrome (IBS) by improving gut microbiota in healthy adults, improve mental state, and sleep quality.

ProDura ® Bacillus coagulans (150 billion cfu/g) 7.26 mg

Bacillus coagulans is a lactic acid that produces spore-forming bacterial species. This formation protects B. coagulans as it travels through the acidic environment of the stomach to reach the intestines. Once it has reached its destination, it begins the process of germination that will aid in the digestion of carbohydrates and proteins.

B. coagulans may also contribute to increased benefits of prebiotics by encouraging the growth of more healthy gut bacteria. A study supplemented B. coagulans for 28 days in elderly subjects was found to have influenced a higher density of healthy gut bacteria.

A review of toxicology testing studies has found that Bacillus coagulans have a history of safety for human consumption.

Lactobacillus rhamnosus (350 billion cfu/g) 7.13 mg

L. rhamnosus is a commonly used strain and appears to be well documented for the prevention and treatment of infections that occur in the gastrointestinal tract. Furthermore, it may play a role in the treatment and prevention of diarrhea and prevent allergic reactions.

A meta-analysis of 12 randomized control studies suggests that Lactobacillus rhamnosus has a role in preventing antibiotic-associated diarrhea in adults who were treated with antibiotics.

A clinical trial was also able to show the ability of this probiotics role in modulating the gut microbiota composition. This eventually leads to a decrease in potentially harmful bacteria and supports the good bacteria.

Lactobacillus plantarum (400 billion cfu/g) 3 mg

These are identified as good bacteria that attack the bad bacteria.

The possible benefits of L. plantarum may include reducing toxins, bloody pressure, fungal activity, and symptoms of irritable bowel syndrome (IBS).

In a clinical trial, L. plantarum was able to decrease symptoms of IBS, particularly the symptoms of abdominal pain and bloating.

While there were no known side effects while taking L. plantarum, there was only one report of an adverse event by transient vertigo in one of the subjects in the trial.

Lactobacillus Casei (300 billion cfu/g) 7.13 mg

Lactobacillus Casei is reported to stimulate the production of lactic acid to help aid in healthy digestion, nutrient absorption, and regularity (gas and bloating).

In a study of 70 patients with constipation were randomized to consume 65 mL of L. casei and noted significant improvement of self-reported symptoms when compared to the control.

Is Multi-GI 5 Safe?

According to the nutrition label found on Unify Health Labs’ website, one scoop contains the 3 blends and is instructed to take twice daily.

The available blends contain ingredients that are associated with side effects that include diarrhea, cramping, flatulence, and constipation. If you do begin to experience these symptoms, stop taking the supplement, and notify your physician immediately.

The dosages of the ingredients are well under the dosages that were used in the studies. Lower dosages combined with natural ingredients provide a favorable safety profile.

It is recommended to take the dietary supplement as indicated on Unify Health Lab’s Website. Dosing of any amount should never be increased.

The Cost

Multi-GI 5 is available on Unify Health Labs website. There are multiple purchasing options and ships to you in 15-20 business days. One container of Multi-GI 5 contains 30 servings.

  • 1 bottle (1 month supply) - $69.95
  • 3 bottles - $188.85 (savings of $21.00)
  • 6 bottles - $353.70 ( savings of $66.00)

Each order is backed by a 90-day money-back guarantee with no hassle. To process your refund, email support@unifyhealthlabs.com or call 800-935-4598.

The Bottom Line

Multi-GI 5 includes 3 blends of ingredients that offer many scientifically proven benefits. As a comprehensive blend with many ingredients, this supplement may support overall gut health.

While the dosing of each ingredient is included and safe, it may be too little to achieve the proposed benefits.

We have reviewed products that seek to promote gut health with comprehensive blends and are similarly priced. You may save by avoiding the need for additional supplements, however.

Before treating symptoms on your own, speak with your doctor first.

Customer Reviews

4.0 Stars out of 86 Reviews
5 Star:44% 4 Star:33% 3 Star:6% 2 Star:6% 1 Star:8%
78% Recommend This Product
Start your review of Unify Health Labs Multi-GI 5:
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Posted on Jan 22, 2021

Multi-GI 5

By Tammi F., Grand Rapids, MI, Verified Reviewer

The product is put together very well.

It tastes great, I love the strawberry lemonade flavor with a hint of pepper. It is very easy to use, and most importantly works great!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons


Ease of use

It works

Pepper burns slightly

Clumps sometimes

Settles in bottom of glass

Posted on Jan 21, 2021

Tasty drink

By Janet F., Gambrills, MD, Verified Reviewer

I take a lot of meds in the morning. There are just so many pills you can take without getting nauseous. This drink tastes good and is easy to go down.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Tastes good

Doesn’t upset my stomach

I like the flavor


Posted on Jan 21, 2021

Easy to use, good results

By Francine C., Fort Wayne, IN, Verified Reviewer

It took a week or so until I realized I was feeling better and have more energy. I am getting ready to reorder. I am on a limited budget but it is worth it.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Easy to use

Flavor is good

Less GI issues

Every time I scoop it out the air fills with this powder, I feel like I am inhaling it

Cost is a bit high given I am on a limited budget

Posted on Jan 19, 2021

Less bloat - more energy

By Robyn L., Lancaster, PA, Verified Reviewer

My husband and I have shared complaints of continually feeling bloated - no matter what we ate - and sluggish. I saw Randy Jackson's ad and it educated me on "leaky gut" and made a lot of sense. So, we decided to give Multi-GI 5 a try for 30 days. Daily I ask my husband, "Well, do you think it's helping?" The first week he said, "I think I feel better..." Now we are on day 25 and he asked me this morning, "Did you order more - it's definitely helping." Now, for him to encourage me to spend money - I know it's making a big difference to both of us and worth it. Tastes pretty good - actually find that I look forward to it in the mornings now.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Removing that "bloated" feel

More energy

Feeling healthier

The powder chokes me when I open the canister

Dissolves ok - but would be nice if it was quicker

A little less expensive - there are 3 of us taking now

Posted on Jan 19, 2021

Great taste

By Shauna C., Fort Wayne, IN, Verified Reviewer

I've been putting my Multi-GI 5 in my smoothie with a frozen banana, strawberries, and water. It tastes like a frozen strawberry banana lemonade. I've lost 22 pounds since I started taking this product and I just ordered 3 more jars!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Healthy effect

Good taste

Decent price

Strong odor when opening jar

Posted on Jan 18, 2021

Great taste

By Jodie L., Oviedo, FL, Verified Reviewer

I’ve been taking this supplement for a couple of weeks now. Love the lemon-lime taste and the ease of preparation.

Began taking it to help with stomach issues which seem to have gotten a little better. I hope it continues to help improve my problems.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons


Take once daily


Posted on Jan 16, 2021

Multi-GI 5

By Kim M., Vista, CA, Verified Reviewer

I bought 4 bottles of the Multi-GI 5 product. I have been taking 1 scoop daily in the morning and have completed 1 bottle so far. My stomach seems to be better, but I am not sure about seeing any increase in energy or weight management. My number one reason for getting this product was to help my stomach. I have been having some serious pain.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Taste way better than I expected

Seems to be improving my stomach issues

No “cons” were specified in this review

Posted on Jan 14, 2021

New user

By Barbara W., Ocean City, MD, Verified Reviewer

I have to say that I've only been using this product for a week or so. I don't notice anything just yet. I'm thinking that in the next week or so I can see good results.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

It is easy to use

I'm not a fan of strawberries so the taste isn't my favorite but I'm still drinking it

Posted on Jan 14, 2021

Almost excellent

By Gayle P., Ava, MO, Verified Reviewer

I’ve only been using this for 1 week so while I cannot comment on how the Multi-GI 5 is working for me, I can comment on the flavor. I was pleasantly surprised and happy about the taste. The strawberry lemonade taste is so good and satisfying. Tastes just like the real thing. For me, it has a slight tingling effect in the back of my throat. Kind of gives me that kick start to my morning. The reason for 4 stars instead of 5 and the "almost" part is that I am having a problem getting it to dissolve in liquid. I have been mixing it with water and I stir and stir and stir and it never completely dissolves. Not so pleasant drinking it with clumps in it. However, I did try mixing it today with Perrier water, I still had to stir and stir but it completely dissolved. Happy I was because I love this product and with the great taste it’s not going to be a product I will tire of drinking on a daily basis. Looking forward to seeing some great results.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons


Does not dissolve quickly or easily

Posted on Jan 13, 2021

First time trying

By Eric R., Apex, NC, Verified Reviewer

It's too early to tell as I'm only on day 4 but I mix it with my post workout protein shake and enjoy the added flavor. I think it's a bit early to expect life-changing results but I have faith in the product as all other medical paths I've gone down have not helped my health. I think I'm on to something here with Multi-GI. Time will tell, I ordered 6 units and will go through all six units and document the improvements in my health.

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Ease of mixing



Maybe the dust when opening

Posted on Jan 12, 2021

Helpful product

By Kay S., Montgomery, TX, Verified Reviewer

I’ve been using this for less than two weeks but will definitely stick with it. The taste is good even when mixed with just cold water. I use a good shaker cup to mix it well. It seems to be helping with my cravings for sugar already and I’m hoping it will do everything that it says it does. We shall see!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

Helps with sugar cravings

Ease of use


No “cons” were specified in this review

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