About Nucific BIO X4

Billed as a 4-in-1 weight management probiotic, Nucific BIO X4 claims to be a “revolutionary new compound” containing 4 proven nutrients that provide digestive support, suppress appetite, and support weight loss management. This includes:

  • 39 billion colony-forming units (CFUs) of a proprietary Digestive Enzyme Blend that helps your body easily digest carbs, fats, and proteins,
  • Green tea to boost your metabolism, and
  • Caralluma Fimbriata to suppress cravings.

Despite these benefits, Nucific’s BIO X4 is claimed to cause no known side effects, contains only 100% pure ingredients, and is made without lactose, gluten, or fillers.

According to the manufacturer, you should take one capsule of BIOX4 with each meal (3 capsules daily), and as long as you exercise regular and don’t eat too many carbs or sweets, you’ll begin experiencing results within 1-2 months.

Whether you’re just starting with a weight loss regimen or have been at it for years, can Nucific BIO X4 provide the digestion support you need to break through your barriers? Consider the following:

Is BIO X4’s Ingredients Effective for Weight Loss?

According to BIO X4’s product label, the supplement contains:

  • Probiotic Blend: 4 billion CFU per capsule – Lactobacillus acidophilus, L. rhamnosus, L. plantarum, Bifidobacterium lactis, B. animalis.
  • Digestive Enzyme Blend: 88mg – Amylase (from Aspergilus Oryzae), Bromelain, Lipase (from Rhizopus Oryzae).
  • Weight Management Blend: 100mg – Green Tea Extract (50% EGCG)
  • Craving Control Blend: 166mg – Caralluma Fimbriata Extract

As we detailed in our Probiotics Buyer’s Guide, probiotics have been used for decades for the treatment of irritable bowel syndrome, allergic response, H. Pylori infection, boosting immune response, and more, and have reams of clinical data proving them to be effective.

Note: Although BIO X4’s website claims that it contains 39 billion CFUs, each capsule only contains 13 billion. In other words, by taking 3 capsules per day, you’ll cumulatively be ingesting 39 billion CFUs. This is important because some consumers shop for probiotics specifically based on the number of actual CFUs each dose provides, and Nucific’s claim might be a bit confusing.

Amylase is “an enzyme that catalyses the hydrolysis of starch into sugars,” and bromelain “is an enzyme found in pineapple juice and in the pineapple stem” that’s used for “reducing swelling (inflammation), especially of the nose and sinuses, after surgery or injury,” and more. Finally, lipase “is an enzyme that catalyzes the hydrolysis of fats (lipids).”

While there are multiple studies related to the oral administration of amylase, clinical support for many of BIO X4’s claims appears to be on the slim side. Likewise, except for treating osteoarthritis and preventing muscle soreness after exercise, there isn’t enough clinical evidence showing that bromelain can provide other benefits.

And other than treating digestive problems related to pancreatic disorders, there is insufficient clinical evidence showing that lipase can provide any other benefits. Similarly, there isn’t enough clinical evidence showing that caralluma can provide any benefits, either.

Finally, epigallocatechin gallate (EGCG), the main ingredient in green tea, is often touted as providing a wide range of benefits, although there is insufficient evidence supporting any of them.

BIO X4 Side Effects

As with most nutritional supplements, even though many of BIO X4’s ingredients may not provide the benefits claimed by the manufacturer, they should be well tolerated by most individuals.

However, the probiotics in BIO X4 may cause a temporary increase in bloating or gassiness, although this side effect should resolve itself over the course of a couple days. Caralluma might also lead to gas, constipation, or stomach pain, which should subside after a week of use.

Green tea extract generally contains at least some caffeine, depending on how it’s processed, so this might be relevant for users who are sensitive to stimulants.

Nucific’s Arbitration Agreement

Finally, it’s important to note that by placing your order for BIO X4, you’ll automatically be bound by an arbitration agreement.

Although this is a fairly common practice among companies who sell most of their products online, if you experienced any damages from using BIO X4, this means that your legal recourse against Nucific would be extremely limited, including becoming part of a trial by jury or joining a class action lawsuit.

What’s the Customer Buzz about Nucific BIO X4?

BIO X4 was a very new product at the time of our research (Nucific’s URL was registered in April 2015 and the company’s trademark was filed in June of 2015), so there weren’t any online reviews available.

Since Nucific is such a new company, they also weren’t listed with the Better Business Bureau.

Nucific BIO X4 Pricing & Refund Policy

The BIO X4 supplement is priced as follows:

  • 1 Bottle (30-day supply): $49
  • 3 Bottles: $129
  • 6 Bottles: $240

According to the product’s website, all orders over $50 come with free shipping.

All Nucific products come with a 90-day refund policy. Although no further details were provided, you’ll need to contact Nucific’s customer service department at 888-679-5520 or support@nucific.com in order to request a refund.

Can Nucific BIO X4 Support Digestion & Weight Management?

While BIO X4’s probiotics will likely provide some level of digestion support (e.g. reducing some types of inflammation, boosting immune response, etc.), unless your intestinal flora is severely out of whack, any benefits you’ll achieve will likely be minor. On top of this, all of the supplement’s other ingredients have insufficient evidence to back up Nucific’s claims.

Considering this, it’s our opinion that BIO X4’s price isn’t in line with any benefits you can realistically expect to achieve from using the supplement.

Tired of Wasting Money? Want to Learn to Shop Smarter?

Join over 3 million HighYa readers who receive weekly how-to guides, tips & reviews and get a FREE COPY of our 145 Scam Hacks e-book. Enter your email below to get started!

794 Consumer Reviews for Nucific BIO X4

Average Consumer Rating: 4.4
Rating Snapshot:
5 star: 527 4 star: 180 3 star: 21 2 star: 22 1 star:  44
Bottom Line: 91% would recommend it to a friend
Showing 1-11 of 794
Sort reviews by:

  • Helped me break the body/weight stalemate

    I have been taking BIO X4 for about 6 months or so and finally broke the stalemate of not being able to get below 150 lbs. I started out a year and a half ago at 186.5 lbs and wanted my goal weight to be 140 lbs. I thought I was asking or hoping for too much; however, I made it to 150-152 and couldn't get below that. I was so frustrated with that! I got discouraged when I couldn't see any progress.

    THEN, I saw an advertisement on Facebook for BIO X4 and read all the information after I clicked on the link! I was pleasantly surprised and thought, "What have I got to lose?!"

    Well, I have finally gotten down to 144 - 146 on a regular basis. I am still hoping for a firmer determination and working on a better frame of mind that I will reach my weight goal of 140. Thanks Dr. Amy to you and your research team who have helped me so much!

    Try it, and you will be pleasantly surprised!

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • 1 out 1 people found this review helpful

    It works!

    • Lake Zurich, IL,
    • Nov 16, 2017
    • Verified Reviewer

    I have only been taking these pills for about a week now and love the results so far. I am definitely not hungry but also not jittery like I have been on other diet pills. Also, I usually take heartburn medication daily but have noticed that I don't seem to have heartburn now. I have lost 3 lbs in one week, and my energy level is through the roof. LOVE THIS PRODUCT!

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • It works!

    • Kentucky,
    • Nov 16, 2017
    • Verified Reviewer

    Ever since I started taking BIO X4, I can see a difference in my body and appetite. Several people at work and home have said they can tell I'm losing weight and I can tell just by looking as well. There are days when I don't even want dinner because I'm still full from lunch, and I don't miss eating dinner when I feel that way either. I will say to get top results you should exercise daily for 20-30 minutes, which I'm starting to do now!

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • No more bloating.

    • North Carolina,
    • Nov 15, 2017
    • Verified Reviewer

    I ordered this product because I used to get bloated after eating any kind of food. I did notice that bloating was no longer an issue once I began using my second bottle of BIO X4.

    I have noticed a slight loss of weight, but this is not my main goal at this moment. Overall, this product is very effective for getting rid of bloating and improving digestion.

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • BIO X4 great stuff

    • Tuscaloosa, AL,
    • Nov 15, 2017
    • Verified Reviewer

    I️ started taking Nucific BIO X4 back in February 2017. I️ have been using it as directed ever since then. I️ have completely stopped taking my Librax for my stomach problems, plus I️ have been able to maintain my weight where I️ want it to be.

    I️ would recommend this supplement to everyone.

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • Great results

    I lost weight within days of starting BIO X4 and am still losing weight. I knew there would be results but I didn't expect how fast they would be. I've lost about 10 pounds. I am still getting results, and others have noticed I lost weight and that feels good.

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • 1 out 1 people found this review helpful

    Happy customer

    I have lost a little weight and need to get rid of 20 more pounds. BIO X4 seems to be doing a good job, and now I need to do the same and stop snacking. I have eliminated sugar from my diet.

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • 3 out 3 people found this review helpful

    Money back guarantee is not legit!

    • Los Angeles, CA,
    • Nov 14, 2017
    • Verified Reviewer

    I recently purchased BIO X4 and tried it for about 45 days. I am vegetarian, gluten-free, only eat fruit sugars and drink about 100 oz of water a day.

    Unfortunately, I did not see any results, and when I contacted support for a refund, as they have a "90-day money back guarantee no questions asked," I was surprised to learn that although it did not work for me, I have to return any bottles I have and will only be refunded for what I didn't use.

    To me, it is a lot of money to take a gamble on a product that may not work, but I placed an order because of their money back guarantee. I am definitely not happy.

    Bottom Line: No, I would not recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (1)
    View all 1 commentsHide comments
    • Nov 16, 2017

      Rachel

      If you want to pay it forward, send it to someone who can really use it and wants to try it. I’d be happy to take it off your hands.

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • 3 out 3 people found this review helpful

    Really amazing.

    • Virgina Beach, VA,
    • Nov 14, 2017
    • Verified Reviewer

    I need to say my overall first month's experience with it has been good. It's helped me get more out of my food, and digestion is a lot more easier than normal. It didn't help too much with weight loss, but it was helping. It also increased my appetite as well, and I was drinking more water than normal throughout the day. I noticed a more positive mood as well.

    It's now been almost a month since I have stopped taking it to see the results. Since I have stopped taking it, I have put on some weight. I find it hard to digest certain foods. I'm still drinking a lot of water, but I'm putting on water weight throughout the day. I miss it already. I hope I can get more soon because I feel my body needs it. I wish there was something stronger I could take for fat burning too.

    One of the biggest benefits I also like about BIO X4 was that in a month it helped to clear up almost all of the back acne I had and troubled spots on my skin. This is some amazing stuff you have worked on and I appreciate your work. Thank you.

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • 1 out 1 people found this review helpful

    Has really helped my digestion

    I have had problems going number 2 for the last seven years. I resorted to taking fiber pills and laxatives daily, two to three times per day. I’ve used this product for a bit more than a month, and I no longer have to use the fiber pills. Very easy bowel movements. I really love this product. In the advertisements they kind of make you think it will help you lose weight. I haven’t, but at least it helps me poop (LOL).

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


  • 1 out 1 people found this review helpful

    It works and no side effects!

    • Washington DC,
    • Nov 14, 2017
    • Verified Reviewer

    I am taking BIO X4 for gut health; IBS-D symptoms and possibly food allergy reactions. I take a BIO X4 five minutes before meals and amazingly, I no longer have IBS-D symptoms, which were extremely inconvenient and constant.

    Some days I don't need to take the BIO X4 at all as my system seems to continue absorbing the supplements for a stretch of days. How cool is THAT?

    I would highly recommend this product to anyone suffering from IBS-D symptoms or food allergies. Thank you SO MUCH for keeping the price reasonable so that many people can once again enjoy a healthier quality of life!

    Bottom Line: Yes, I would recommend this to a friend

    Help others find the most helpful reviews

    Was this review helpful?

    yes no
    Comments (0)
    View all 0 commentsHide comments

    Do you have an account? Log In before commenting.

    (If you don’t have an account – don’t worry, you can create it after)


Showing 1-11 of 794

Write a Review for Nucific BIO X4!

Share your experience to help others shop smarter & discover great products.

Write a Review