About Profemin

By Derek Lakin
HighYa Staff Updated on: Sep 26, 2017

Profemin is a natural supplement formulated with an exclusive blend of botanicals the company claims can help effectively reduce and relieve the symptoms of menopause and perimenopause, without the use of hormones.

Specifically, the manufacturer tells us that by taking one capsule of the supplement in the morning and another at night, women can help address their gynecological health, experience anti-inflammatory and pain-relieving benefits, and even improve their circulatory function.

Their website indicates that Profemin was even shown in a double-blind, placebo controlled study to have provided “significant improvement in the major symptoms of perimenopause and menopause” for 96.6 percent of participants.

Can you realistically expect to experience the same? That’s why you’re here, so keep reading and we’ll help you uncover answers to some of your most important questions.

What Is Menopause & What Causes It?

According to the National Institute on Aging, “Menopause is a point in time 12 months after a woman’s last period. The years leading up to that point, when women may have changes in their monthly cycles, hot flashes, or other symptoms, are called the menopausal transition, or perimenopause.” For most women, this occurs between the ages of 45 and 55.

This 7-14 year transition is largely caused by greatly varying estrogen and progesterone hormone levels, which can decrease bone density and cause weight gain.

As mentioned on the Profemin website, this can also potentially lead to additional side effects like lack of focus, decreased libido, sweating, moodiness, joint pain, trouble sleeping, irritability, fatigue, and low energy levels.

Because of these varying hormone levels, one common treatment for the symptoms of menopause is hormone replacement therapy (HRT). While it can be effective, WebMD reports that common HRT side effects include a higher risk of breast cancer, heart disease, stroke, and blood clots.

Can Profemin’s ingredients provide similar benefits as hormone replacement therapy, but without the potential risks?

Taking a Closer Look at Profemin’s Ingredients

According to the supplement facts label listed on the Profemin website, its formula contains:

Profemin proprietary blend 257mg: Standardized extracts of Angelica gigas root (35%), Phlomis umbrosa root (32.5%), and Cynanchum wilfordii root (32.5%)

After reaching out to the company, we received a copy of a 2014 South Korean study involving 104 female participants with menopausal symptoms, between the ages of 40~70. The study lasted 12 weeks, was double-blind, randomized, and placebo-controlled, and occurred across more than one location.

Note: While the supplement’s name used in the trial was EstroG-100, it contained the exact same ingredients formulation found in Profemin.

To gauge the effectiveness of the supplement, participants filled out questionnaires assessing quality of life using the Kupperman Menopause Index (KMI), from baseline to week 12.

In the end, the study concluded that EstroG-100/Profemin’s specific combination of ingredients “statistically significantly improved the quality of life [across] nine different symptoms [such] as hot flush, paresthesia, nervousness, melancholia, vertigo, fatigue, rheumatic pain, formication, and vaginal dryness.”

Could Profemin’s Ingredients Cause Side Effects?

Just because it’s advertised as natural, does this necessarily mean Profemin’s ingredients are safe?

According to the clinical study mentioned in the previous section, the supplement’s proprietary blend did not result in any harmful side effects, which is however, like any other dietary supplement, it’s important to speak with your healthcare provider in advance.

How Much Does Profemin Cost?

Profemin was available through three different offers at the time of our research:

  • TV Offer – Two bottles (60 capsules in each) and a copy of "Feeling Great Naturally – the Menopause Survival Guide" for $9.95 S&H. After 30 days have passed, you’ll be charged $39.95 per bottle ($79.90 total). Every 60 days thereafter, you’ll receive another two bottles and charged $79.90 each time.
  • Best Value Offer – Two bottles (60 capsules each) and a copy of "Feeling Great Naturally – the Menopause Survival Guide" for $34.95 per bottle plus $9.95 S&H (total of $79.85). Here again, after 30 days have passed, you’ll be enrolled in an autoship program, sent a fresh supply every 60 days, and charged $79.90 plus $9.95 S&H each time.
  • Good Value Offer – A one-time, 30-day supply of Profemin for $59.95 plus $9.95 S&H. No recurring shipments thereafter.

The supplement’s commercial advertises the ability to purchase a 30-day supply of Citratrim, the company’s fat loss supplement, for an additional fee.

According to the representative we spoke with, Profemin comes with a 30-day refund policy, less S&H charges. Customer support can be reached at 800-221-0905 or customerservice@profemin.com.

What’s the Deal With Profemin’s Arbitration?

Per the terms listed on the supplement’s website, all direct sales of Profemin are bound by an arbitration agreement. What’s this?

In a nutshell, it means that if you have a legal issue with the company, you agree to bypass the courts and settle the dispute via binding arbitration. While this is extraordinarily common in today's marketplace, as consumers ourselves, we feel it's worth emphasizing.

Are Customers Leaving Positive Reviews For Profemin?

Since performing our original research, 15 HighYa readers had provided feedback about Profemin, giving the supplement an average rating of 2.5 stars.

Most compliments appeared to revolve around effective results (e.g. decreased hot flashes, improved sleep, reduced sweating, etc.), while many complaints related to no results and unknowingly being signed up for recurring shipments. With this said, the autoship details on the site seemed crystal clear at the time of our research.

On Amazon, more than 120 customers had given Profemin a similar average rating of three stars. Many referenced the same compliments and complained about no results, although no mentions were made about recurring shipments.

From a company perspective, Profemin is brought to you by Thera Botanics, a popular manufacturer that also makes Prosvent and Cebria. Under the Profemin name, they held an A+ Better Business Bureau rating and three closed complaints as of 8/9/17.

Only one of these complaints provided details, which referenced fraudulent charges. The company seemed to respond quickly with a solution.

How to Choose a Menopause Supplement?

Searching online for menopause supplements returned hundreds of results through Google—and while none contained the exact same formulation, many contained some of the same ingredients and promised to address the same side effects.

Some of these options were priced as low as $6, while others exceeded $50, putting Profemin’s per-bottle price somewhere near the middle (depending on your ordering choice, of course). How can you make the most informed decision?

Starting out, it’s important to emphasize that according to many prominent health organizations like the National Institutes of Health, dietary supplements are not recommended for otherwise healthy individuals (i.e. those not deficient in any of the ingredients they contain).

And since menopause isn't considered a disease or deficiency, this means that it’s important for you to speak with your doctor about any supplement’s real-world potential to ease your symptoms.

Speaking of which, another important consideration is that even some of the most popular natural ingredients used for menopause relief, such as black cohosh, dong quai, evening primrose oil, ginkgo, hops, red clover, soy, St. John’s wort, vitamin E, and wild yam are reported to have insufficient (or inconclusive) evidence for their effectiveness.

In fact, only ginseng is reported by Health.com to have the potential for addressing menopausal symptoms, although it can cause some serious side effects in women, such as heart problems.

Let’s carry this thought over to the final section.

What’s the Bottom Line About Profemin?

In the end, like any other dietary supplement, there’s no way to know if Profemin will work with your specific biology without giving it a try.

However, the company provided us with a copy of a clinical study that found the supplement’s specific blend of ingredients has been shown to significantly reduce self-reported menopausal symptoms.

In addition, here on HighYa and on Amazon, the supplement had garnered a mostly positive online reputation with customers, and the manufacturer stands behind it with a risk-free 30-day trial, although you’ll be out a few bucks in S&H if you’re dissatisfied.

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15 Consumer Reviews for Profemin

Average Consumer Rating: 2.5
Rating Snapshot:
5 star: 3 4 star: 1 3 star: 1 2 star: 5 1 star:  5
Bottom Line: 40% would recommend it to a friend
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  • 19 out 19 people found this review helpful

    It is a good product for Menopause

    I've been using Profemin for about two months. After using it I haven't had any hot flashes and was able to do my daily routine without worrying about it anymore. I was also able to have better sleep in the night.

    Bottom Line: Yes, I would recommend this to a friend

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  • 20 out 21 people found this review helpful

    Love it!

    • California,
    • Aug 26, 2016
    • Verified Reviewer

    I've been using Profemin for about a month now. Literally after the first use I haven't had any hot flashes and have been sleeping like a baby.

    I ordered through Amazon as I wanted to try first and I must admit that it is working great for me.

    I definitely recommend this product

    Bottom Line: Yes, I would recommend this to a friend

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  • 27 out 30 people found this review helpful

    Nurse

    • Omaha, Nebraska,
    • Apr 23, 2016
    • Verified Reviewer

    I love Profemin. I've been taking it for 2 weeks now, and I fell so good. I used to have hot flashes every 45 minutes, I was so embarrassed when I was in public, my face dripping sweat and my makeup would be smeared. Thank God for Profemin. And it's natural.

    Bottom Line: Yes, I would recommend this to a friend

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  • 79 out 83 people found this review helpful

    False information

    • High Desert,
    • Aug 8, 2015

    Even though I felt less severe hot flashes, I just canceled my subscription. I called to ask why I was charged on the 4th of Dec and again on the 29th. Was told if product was not returned within 30 days they charge you. Saying this is stated in the paperwork that comes with the product. I read to her exactly what my order form said and that nowhere does it state that. She was argumentative and rude. There are other products for a lot less to try.

    Bottom Line: No, I would not recommend this to a friend

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    • Feb 15, 2015

      Rita

      Does this pill really work? Someone help me.

    • Mar 2, 2015

      Pamela

      No it doesn't work so don't waste your time or money. Look into a supplement called DHEA. It worked for me.

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  • 56 out 59 people found this review helpful

    It does help, but what is in there?

    • Eureka, CA,
    • Jul 21, 2015

    I bought Profemin through eBay, paying a lot less. I took it for a couple of months and found my hot flashes and night sweats greatly reduced. However, I am rather nervous about the ingredients. I have developed severe headaches over the last few weeks and am wondering if these pills may be the cause. I have stopped taking them. "Proprietary Blend" can mean anything. What is really in there? I am not willing to take that risk.

    Bottom Line: No, I would not recommend this to a friend

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  • 62 out 66 people found this review helpful

    Please Read Before You Buy

    • Williston, ND,
    • Jul 15, 2015

    I bought this and used it for two months. I took it to get rid of hot flashes and night sweats. It made them worse. I called the company and they said I was not giving it enough time. So took it another month. Then told them I would like to cancel. I still got a shipment on the tenth of March and was told it had to be back in there hands on the 21st. Also had to do all kinds of stuff to package to send back. But they were willing to offer me a 20% discount if I did not want to go through the hassle of sending it back! What a scam.

    Bottom Line: No, I would not recommend this to a friend

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  • 43 out 45 people found this review helpful

    Two months and no difference

    • Utah,
    • Jul 15, 2015

    I started taking this on December 1st and now into February, I'm still taking Profemin and never missing a dose. I'm not even seeing a small difference in my hot flashes or sleeping. As I'm writing this review, I'm getting hot flashes so in my opinion this product does not work and do what it was supposed to do. Please don't waste your money like I did.

    Bottom Line: No, I would not recommend this to a friend

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  • 32 out 37 people found this review helpful

    I'm menstruating again.

    • Poconos, PA,
    • Jul 13, 2015

    I started taking Profemin two weeks ago and it helped with being hot. But after going six months without menstruating, I was wondering why I am now having a period again? I'm sending them back.

    Bottom Line: No, I would not recommend this to a friend

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  • 29 out 34 people found this review helpful

    I'd recommend Profemin.

    • Cleveland, OH,
    • Jul 13, 2015

    I've been taking Profemin for three weeks now. The first thing I recognize was my irritability and moodiness less severe. I could go from 1 to 100 in a minute and the stress of it. Now my moods are calmer and I can think clearer. I sleep better, can lay down and fall asleep. No more vaginal dryness and best of all I am not fatigued when I wake. I'm also ok with the pricing because I chose the vitamin d blend, so roughly I'm paying $50 a month. So it's $100 bi-monthly. I'm okay with it because I truly wanted to feel better and I truly do. It felt good to be calm when I was challenged by my everyday life and not to respond the way I was accustomed to. I'd recommend Profemin and hope it gives you the same effect. It's been roughly three weeks, I'm hoping this does it.

    Bottom Line: Yes, I would recommend this to a friend

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  • 58 out 62 people found this review helpful

    I will not recommend it.

    • Michigan,
    • Jul 9, 2015

    Maybe to other people this product works, but I called to order on 10/31 and they told me clearly that it would take 2 to 3 weeks to receive. Well I received the product on the second week of December and I was giving it time to work. Then I went to use the little money I had in my account but they took $79.90 from my bank account.

    I called them and some very rude man told me that they took the payment because they had delivered the product on the 6th of November but I explained to him that this wasn't the case yet he just said that they had proof with a tracking number and that I should call my post office.

    I did call my post office and they didn't even want to check on the tracking number. They told me that if it was more than a month then there was nothing they could do. I really think that it's not fair for this company to do this to honest people.

    I don't know if I was the only one that experienced this but I'm going to talk to a lawyer to see what they advise me. My advice to others is to be very careful.

    Bottom Line: No, I would not recommend this to a friend

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    Comments (2)
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    • Jan 3, 2015

      JANNIE SULL, MAINE

      I got the worst heartburn from this that I thought I was having a heart attack. If you are on other medication, check first and make sure it doesn't interact with prescription meds.

    • Feb 18, 2015

      Anonymous

      This company is a fraud! Do not, I repeat do not, buy these crap pills.

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  • 18 out 20 people found this review helpful

    It works for me

    • Crestview, FL,
    • Jul 4, 2015

    I am been using this product for six months and it reduced a lot my menopause symptoms. I been having circulation problems with different hormones treatments so I decided to try Profemin and so far I like it. Every woman goes through menopause in different ways and Profemin works for me. The only issue is that it's quite expensive.

    Bottom Line: Yes, I would recommend this to a friend

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    • Jan 29, 2017

      Mary Martinez

      If you like Profemin so much why did you give it only one star?

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