Gundry MD Vital Reds Reviews - Is It Safe and Effective?

By HighYa Research Team
Updated on: Jan 23, 2020

Medically Reviewed by Anthony Dugarte, M.D., C.S.C.S

What Is Vital Reds?

Vital Reds is a powdered blend of polyphenol-rich superfruits, natural fat-burning ingredients, and probiotics that Gundry MD advertises will help increase your natural energy, promote digestion, and improve the health and appearance of your skin.

Additional benefits noted on the website include better food metabolizing, less gas and bloating after meals, smoother bowel movements, and “the feeling of finally having the power to start getting your weight under control.”

Gundry MD states that you need to mix one scoop of Vital Reds berry-flavored, quick-dissolve formula with a glass of water or the beverage of your choice, and enjoy once per day, with or without food. From there, its soy, sugar, and artificial sweetener-free blend will get to work.

Combining our in-depth research and interviews with professionals, this review takes a detailed look at Vital Reds’ formulation, the available clinical evidence for Gundry MD’s claims, and the supplement’s close competitors—all so you can decide whether or not to buy.

How Do the Polyphenols in Vitals Reds Work?

Polyphenols are naturally occurring micronutrient compounds found in plants that give them their color and help protect them from external threats.

In humans, Dr. Jason Reed, founder of BestRxForSavings says, “the most likely reason polyphenols are beneficial is since they have antioxidant properties.”

They “prevent free radicals (electrons that bounce off of atoms) from bouncing around inside our bodies and causing a host of [inflammation-based] issues,” he adds, such as atherosclerosis and arthritis.

However, Reed points out that the human body doesn’t require polyphenols to maintain good health. Furthermore, it doesn’t necessarily take dozens of “exotic” ingredients—as Gundry MD advertises for those in Vital Reds—to reap the potential benefits polyphenols might provide, he said.

“Eating the recommended daily amount of fruits and vegetables will provide plenty of polyphenols,” he advises.

With these details in mind, let’s zoom in and take a closer look at what you’ll consume with each scoop of Vital Reds.

Vital Reds Ingredients

Gundry MD advertises that Vital Reds contains the following 100% natural and pure ingredients:

  • Thiamin 1.5 mg
  • Riboflavin 1.7 mg
  • niacin 20 mg
  • Vitamin B6 2 mg
  • Folate 667 mcg DFE (400 mcg folic acid)
  • Vitamin B12 6 mcg
  • Biotin 300 mcg
  • Pantothenic Acid 10 mg
  • Selenium 70 mcg
  • Chromium 200 mcg
  • Reds Blend 1,760 mcg – Carrot, organic apple peel, grape skin extract, Aronia berry extract, organic flaxseed, grape seed extract, acai fruit extract, acerola fruit extract, apple, apple pectin, organic beetroot, blackberry, European black currant fruit extract, blueberry fruit concentrate, cranberry fruit extract, mango, mulberry fruit, papaya, pomegranate, red raspberry, strawberry, cantaloupe, cherry, grape, grapefruit, lemon, lime, orange, peach, pear, pineapple, plum, watermelon, berberine hydrochloride
  • Metabolic Enhancing Blend 365 mg – Cinnamon bark 5:1 extract, green tea leaf extract, white tea leaf extract, ginger root, turmeric root extract, bitter melon fruit extract, black pepper fruit
  • Digestive Support Blend: Probiotic Blend 3 billion CFU – Bacillus coagulans, Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus reuteri
  • Fructooligosaccharides 250 mg

The US Department of Agriculture recommends that adult men and women eat at least two to three cups of vegetables per day, along with one-and-a-half to two cups of fruit.

With this said, the Centers for Disease Control reports that as of 2015, “just 9 percent of adults met the intake recommendations for vegetables,” and “only 12 percent of adults met the recommendations for fruit.”

As such, Reed tells us, “if a patient did not eat a healthy diet that provided the recommended daily allowance of vitamins and minerals, then it appears Vital Reds could be a benefit.”

Still, he notes, he is “not familiar with this product and given that it is a dietary supplement that doesn’t have to meet the same FDA requirements on efficacy and safety, I can’t say for sure.”

We also know that the medical community has used probiotics—beneficial bacteria strains like Bifidobacteria and Lactobacillus—for decades to help balance digestion, reduce gassiness and bloating, and even boost immune response.

Over the last several years, probiotic supplements have become popular among consumers as well, who use them to achieve many of the same benefits.

Is There Any Science Backing Gundry MD’s Claims?

Though Vital Reds has not been specifically tested in randomized trials, some of the individual ingredients have been previously studied. In this section, we’ll highlight scientific support for a few of the ingredients included in Vital Reds.


Vitamin B deficiency can be associated with a wide array of unwanted effects like itchy skin, impaired mental capacity, and nerve issues. Those that that choose a plant-based nutrition plan are most at risk.

Folate is necessary for growth and development. It is especially important in pregnant women as a deficiency can be associated with congenital disabilities. The RDA for folate in adults is 400mcg, though the dose offered in Vital Reds is sufficient even for the demands of an expecting mother.

B12 deficiency can be associated with anemia as it has a role in supporting proper red blood cell function.

Though they serve essential functions, B Vitamins are unlikely to play a role in the proposed energy-boosting effects of Vital Reds as scientific support for this action is limited.


Selenium is an essential mineral. It is commonly found in soil, water, and eggs.

200mcg daily over the course of 8 years did not prevent diabetes when compared to a placebo. In fact, those with the highest levels were at an increased risk for the disease.

A review of 12 studies did not find a statistically significant improvement in short or long-term regulation of blood sugars.

This mineral may actually negatively impact energy metabolism, particularly in those with diabetes.

You can get chromium in beef, fruits, broccoli, and whole wheat. Thought to boost the function of insulin, this mineral has been well studied in humans.

A review found that chromium did not benefit glucose or insulin regulation at doses ranging from 10-1000mcg daily.

A review found that when chromium is offered as brewer’s yeast at doses ranging from 42-1000mcg, it can mildly impact fasting blood glucose in diabetics.

Chromium supplementation in overweight and obese subjects may offer mild weight loss benefits.

Available support for chromium’s effect on carbohydrate energy metabolism and weight loss is mixed.

Reds Blend

Grapeseed extract may to be rich in antioxidants.

Oxidative damage was 1.5x greater in healthy subjects that were not treated with 300mg of grapeseed extract.

100mg doses every 6 hours reduced oxidative stress in patients receiving coronary bypass surgery when compared to the control group.

Beetroot is low-calorie, high fiber, and may offer a number of health benefits.

A review of 43 randomized trials found that beetroot juice doses ranging from 70-500mL lowered blood pressure when compared to placebo. Higher doses were associated with blood pressure reduction comparable to results achieved with a single medication or the DASH diet.

Berberine may offer anti-inflammatory and neuroprotective capabilities. Berberine reduced body fat and enhanced insulin sensitivity in obese, diabetic mice.

In human subjects, those with metabolic syndrome that were treated with 500mg of berberine three times daily over 3-months had remission of the syndrome, decreased waist circumference.
Ingredients found in Reds Blend may improve carbohydrate energy metabolism, blood pressure, waist circumference, and metabolic syndrome.

Metabolic Enhancing Blend

Cinnamon bark may to offer both antioxidant and disease-fighting benefits.

5g reduced post-meal blood glucose levels in obese women. A review confirmed these findings, particularly at doses ranging from 120mg/d - 6 g/d over 4 to 18-weeks.

Turmeric may offer anti-inflammatory, heart health, and brain-boosting effects likely related to curcumin, a molecule produced by turmeric plants.

A review found that curcumin dosing ranging from 70 to 3,000mg per day for 2 to 3-months reduced BMI.

Another review concluded that curcumin doses ranging from 250 to 2.4g reduced both BMI and body weight in subjects with metabolic syndrome, obesity, heart disease, and diabetes.

Black pepper may offer antioxidant, anti-inflammatory benefits, and disease-fighting capabilities.

6mg of black pepper daily reduced BMI and body fat, while improving the insulin sensitivity of overweight subjects.

This spice may also boost the actions of turmeric and friendly gut bacteria like Bifidobacterium and Lactobacillus.

The ingredients found in the Metabolic Enhancing Blend may reduce BMI, body weight, and body fat while supporting carbohydrate energy metabolism.

Digestive Support Blend

Probiotic strains play a role in many functions vital for health in addition to offering dietary support. L. acidophilus may relieve diarrhea and bloating while boosting immune function. B. bifidum strains may benefit inflammation, immune support, and allergy relief.

Different strains, dosing regimens, and probiotic combinations were investigated in a review of 20 trials; they concluded that Lactobacillus and Bifidobacterium strains are associated with fewer sick days due to respiratory infections.

Side Effects

The Gundry MD website emphasizes that the natural, mostly food-based ingredients found in Vital Reds are 100% safe, as every batch is tested in the USA at a cGMP-certified facility. Then, it’s rechecked for purity, content, and dosage by a third-party lab.

Still, side effects are always a possibility with any dietary supplement, as are medication interactions, which is why it’s important to speak with your doctor before making any purchases.

Even at doses at 1500mcg daily, B12 was without serious side effects. Toxicity is rare, though reported side effects can include nausea, vomiting, and skin flushing.

Chromium dosing up to 1000mcg was without serious adverse events, though diarrhea, headaches and rash have been reported. No serious adverse effects were reported in 10 randomized trials with cinnamon doses up to 6g/day.

Turmeric’s active ingredient, curcumin, was safe at doses ranging from 3600-8000mg each day for 4-months, with only mild nausea and diarrhea reported.

Black pepper is also generally safe. Doses at 6mg daily were without serious side effects over 2-months.

Also, according to Reed, the green tea extract’s caffeine could raise your blood pressure, which is a drawback for someone who already deals with high blood pressure.

We’ve also learned during our past research that probiotics can initially lead to many of the side effects they’re supposed to treat such as gassiness and bloating, which typically subside quickly.

Testing for individual strains in research studies is often safely done at doses larger than the combined total found in Vital Reds.

How Much Does Vital Reds Cost?

Gundry MD prices each jar of Vital Reds as follows:

  • 1 Jar: $69.95
  • 3 Jars: $199.36 ($66.45 per jar)
  • 6 Jars: $377.73 ($62.96 per jar)

We also found Vital Reds sold on Amazon for $47.99 per 4 oz. jar at the time of our research.

All direct U.S. orders include free shipping, along with a 90-day guarantee. To request one, you’ll need to call (800)852-0477.

Vital Reds vs. Competing Polyphenol Supplements

There are perhaps hundreds of powders, antioxidant formulas, and polyphenol supplements competing for your business.

Many of these boast the same features as Vital Reds as well, including a wide assortment of fruit and vegetable extracts, a few different probiotic strains, and formulas that are free from sugar, sweeteners, artificial ingredients, and caffeine and other stimulants.

Here were some of the top-rated results in Amazon:

Brand Price / Cost Per Serving Number of Ingredients Notes
Vital Reds $69.95 / $2.33 55 90-day refund policy
Superfood Vital Reds with Greens $39.97 / $1.33 63 Available in cocoa, mocha, and very berry flavors
Purity Products Super Reds $24.95 / $0.83 47 No probiotics
RealDose Essentials Real Reds $46.95 / $1.57 9 1-year money back guarantee
Organifi Green Juice $69.95 / $2.33 13 60-day refund policy,

While you certainly have a lot of options, choosing the right one might be as easy as deciding which factors to emphasize.

For example, if the price is your number one concern, Vital Reds and Organifi Green Juice tie for the highest cost per serving among popular competitors above. Country Farms comes in meaningfully lower, although since each jar only contains 20 servings, you’ll likely have to reorder more often—or order larger quantities at the same time, thereby increasing your upfront costs.

Formulation-wise, RealDose has the fewest ingredients, while Superfood Vital Reds comes with the most. Note: KaraMD offers a very similar formulation as Vital Reds, but at a price that’s almost 60% lower.

Coming in close behind is Organifi, which offers the second-fewest ingredients in its formulation and also ties with Vital Reds for the highest price per serving.

Furthermore, the manufacturer only gives you 60 days to try Organifi out, whereas RealDose ’s one-year satisfaction guarantee awards them with the lengthiest refund policy.

An important thing to keep in mind is that more polyphenols doesn’t always mean better absorption, Reed noted.

It’s difficult to say which supplements in the chart absorb better into your body than others, as information about their polyphenols is limited. In our opinion, the best course of action is to take all factors of a supplement into account rather than focusing on which one has the most polyphenols.

Bottom Line: Should You Order Vital Reds?

Here on HighYa, more than 1,346 readers have given the Vital Reds powdered supplement an average rating of 4.3 stars, with nearly 90% saying they would recommend it to a friend.

It’s also much the same on the Gundry MD website, as well as third-party sites like Amazon. As such, it seems that most customers who give the supplement a try are pleased with their experience.

With these positives in mind, Reed emphasizes that most of us can get all the polyphenols we need just by eating the recommended daily allowance of fruits and vegetables.

If you’re willing to invest minimal time into altering your eating habits, you might be able to forego supplementation altogether.

But, even if you’re willing to pay for the convenience of getting your daily fruit and veggie allotment via a powdered drink mix, it’s difficult to ignore the fact that Vital Reds costs meaningfully more than many other polyphenol-focused competitors.

We reached out to Vital Reds multiple times to inquire about which factors influence their higher-than-average pricing but were not able to get an answer. Therefore, we think it’s difficult to recommend Vital Reds to customers who are looking to achieve the most value for their money.

If you think your diet is lacking key nutrients, the first step should be seeking the opinion of a medical professional. They can help you determine what may be missing, and identify all of the possible treatment options.

Customer Reviews

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  • 1351 Customer Reviews
  • 89% Recommend This Company
4.3 out of 5
5 star: 62% 4 star: 23% 3 star: 3% 2 star: 1% 1 star: 7%

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  • Vital Reds is excellent

    • By Roberto Garza,
    • Fort Worth, Texas,
    • Jan 26, 2017
    • Verified Reviewer

    Thank you, Doctor Gundry, for an excellent product. Vital Reds has helped me to feel more energetic and healthy. The reoccurring monthly order option is very convenient.

    Bottom Line: Yes, I would recommend this to a friend

  • Radiation Therapy

    Although I have been undergoing radiation therapy, which makes me tired and lethargic, the Vital Reds seem to be making me more energetic.

    Bottom Line: Yes, I would recommend this to a friend

    • Aug 2, 2016

      Company Response from Gundry MD

      Hi Colby,

      We are thrilled to hear about the energy Vital Reds has helped you with. Thank you so much for sharing your positive experience with us, we look forward to serving you for many years to come!

      -Aria, Customer Advocate Gundry MD

  • Energy has returned

    • By Rick,
    • Corona, CA,
    • Aug 1, 2016
    • Verified Reviewer

    I've been taking Vital Red mixed in water every afternoon when I normally get really tired. My energy level has without a doubt went way up. I also wake up feeling more rested, then I take an hour walk which in turn also makes me feel better throughout the day. I had lost a lot of my energy due to hypothyroidism, I had cancer of the thyroid. Once it was removed my energy didn't seem to come back even with the medication. This product definitely is a part of me getting my energy back and weight under control. I recommend this product.

    Bottom Line: Yes, I would recommend this to a friend

    • Aug 2, 2016

      Company Response from Gundry MD

      Hi Rick,

      My name is Aria, customer advocate at Gundry MD. I wanted to personally reach out and thank you for sharing your feedback and wonderful experience you have had with Vital Reds.

      If you ever have any questions, please do not hesitate to contact me at I am excited to hear more about your experience with our products!

  • Very pleased

    • By Joe,
    • Virginia,
    • Aug 6, 2016
    • Verified Reviewer

    I have never wrote a review for anything but felt compelled to write this one. I have had a few health issues lately and have felt very rundown and tired for over a year. My vitamin D levels have been low and it's been hard to work. I've had to force myself to get going in the mornings and by lunchtime I'm whipped. My wife wanted me to give this product a try so she purchased it for me. Everyone is different but for me it has been amazing.

    After three weeks I feel better than I have in a long time. I get an immediate boost that seems to last all day with no crash. It even seems to calm me down. I was very skeptical of this product but for me it works great. Taste terrible but works great!

    Bottom Line: Yes, I would recommend this to a friend

  • Highly recommended

    • By Sarah Bull,
    • California,
    • Aug 6, 2016
    • Verified Reviewer

    I started using Dr Grundy's Vital Reds 5 weeks ago along with a low carb diet. In the past this diet has been effective for my weight loss goals but always left me feeling extremely low on energy.

    Since taking Vital Reds I continue to feel alert and energized through out my whole day. It somehow even seems to have helped with my sleep cycle. I used to sleep 8-10 hours and wakeup feeling not fully rested. Since 4 weeks I have been sleeping 7 hours a night. I have been waking up without an alarm and feeling fully rested.

    The price seemed high to me at the beginning, $100 for 3 jars. But at week 5, I still haven't gotten through my first jar, which means for less then $30 a month I get to feel so much more natural energy that makes life so much more enjoyable. That is crazy.

    Bottom line: I love Vital Reds and would highly recommend it.

    Bottom Line: Yes, I would recommend this to a friend

  • Five Stars

    • By Deborah Hale,
    • Pineville, WV,
    • Aug 7, 2016
    • Verified Reviewer

    Just had blood work taken and my cholesterol went from 168 to 151 and I give Vital Reds the credit. But I must admit the taste is something you have to acquire, I mix it in the morning and put it in the freezer until ice cold, not frozen, so it is so much better.

    Bottom Line: Yes, I would recommend this to a friend

  • Vital Reds

    Vital Reds supplies delivers the health-promoting benefit of fruits without the load of sugar that would come along with them if eaten separately. It's an efficient and cost-effective way to get what your body really needs! I've been using it for a few weeks and feel great!

    Bottom Line: Yes, I would recommend this to a friend

  • Vital Reds are amazing!

    • By Deb,
    • New York,
    • Aug 7, 2016
    • Verified Reviewer

    I must admit I was skeptical, however, in one month I feel amazing! I am energetic and sleeping much better too. My skin, hair, nails are healthy and have a glow. I get compliments all the time on how healthy I look for my age (60) and asked what's my secret. Of course I tell them Vital Reds. Thank you so very much Dr, Gundry for this amazing product. New lifetime fan.

    Bottom Line: Yes, I would recommend this to a friend

  • Surprising side effects?

    I've been very diligent with taking Vital Reds for the past month, reducing lectins in my diet, and starting each day with a recommended Dr. Gundry smoothie. So, is it the vital reds, or the whole new program I've been encouraged to adopt. I've experienced renewed energy, my skin is looking better than it has in years, and because of that, I am feeling more optimistic and even have a renewed interest in our love life.

    Bottom Line: Yes, I would recommend this to a friend

  • Excellent way to get what your body needs!

    • By Richard,
    • California,
    • Aug 8, 2016
    • Verified Reviewer

    I was a bit skeptical at first but once I started in on the vital reds for awhile I realized that this was different from the multitude of other health products. Now there is a way to get what your body needs without all the hassles or fuss!

    I mix mine into a small drink in the morning and off I go knowing that I am nourishing my body with the best that it can get!

    Bottom Line: Yes, I would recommend this to a friend

  • Better than expected

    • By Jodi Spade,
    • New York,
    • Aug 8, 2016
    • Verified Reviewer

    I first have to say that I hate the commercials that are all talk like the one for this product. However, I have to say it sucked me in because I agreed and kept agreeing with everything said and purchased the product at the end with hope that it was what it promised to be.

    When I got the Vital Reds I tried it immediately and loved it! The energy was a clean feeling that never let you down, the taste is so good you could drink it all day. I now have to hide it from my family or it will be gone. It makes me feel great and is good for me. I mix it with seltzer water for a fruity soda, since I don't drink soda. I also try to not have sugar, so this is like a perfect replacement.

    Thank you for making such a high quality product, we love it!

    Bottom Line: Yes, I would recommend this to a friend

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