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Hempvana Pain Relief Cream Reviews

Hempvana Pain Relief Cream

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29 Customer Reviews

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Hempvana pain relief cream is a topical analgesic that claims to provide relief from joint and muscle pain. A review of studies suggests that topical pharmaceutics' application may provide more short-term relief of minor aches and pain.


  • Active ingredient dosage formulated to offer deeper penetration to tissues
  • Easy to use and affordable


  • Studies are lacking showing long-term effectiveness of a topical application
  • Relief of pain is short term

Hempvana Pain Relief Review: Is It Safe and Effective?

By Rocklend Davis, Ph. D.

Updated on: Jul 20, 2020

Pain management options vary as the underlying cause can significantly differ from person to person.

There are many treatment options available to manage symptoms of pain include, including heat and cold packs, herbal supplements, over the counter medications, Physical Therapy, prescription medications, or surgery.

Topical pharmaceutical products such as Hempvana pain relief cream, when applied, seek to target the local area below the skin.

The active ingredients found in these pharmaceutical products are alleged to help facilitate deeper penetration into tissues at a rapid rate.

According to Hempvana, daily application will provide you with the following benefits:

  • Relieves pain and inflammation
  • Great for arthritis and muscle soreness
  • Treats pain, not your whole body

The method regarding the topical analgesics is to reduce the need to take pain treatments orally that may contribute to gastrointestinal issues. It may be a formidable alternative to address conditions related to OA when compared to oral ingestion.

In this review, we’ll describe intended use, as well as the scientific backing of Hempvana Pain Relief Cream active ingredient.


Topical analgesics can be applied directly onto your skin at a site(s) in which you are experiencing pain.

According to the product description, Hempvana pain relief cream is intended for adult use only and can be applied up to four times daily.

The application begins by massaging a generous amount of the pain relief cream to the painful area (shoulders, elbows, wrists, knees, calves, and back) until it is thoroughly absorbed into the skin.

Is There Any Science Supporting Trolamine Salicylate 10%?

Trolamine Salicylate is used to treat minor aches and pains in the muscle and joints, such as arthritis, backaches, and sprains.

Trolamine salicylate is offered as a topical analgesic that is suspected to be a more effective and alternative means to minimize the adverse drug effects and complications of systemic analgesic use.

Salicylates specifically (provides the analgesic effect) are found in aspirins, which provide interference with inflammatory pathways.

Two studies show that a topical analgesic with salicylates compared to taken orally was associated with improved pain relief.

Based on blood samples and muscle salicylate levels, at least 82% of topically applied trolamine salicylate was absorbed during a period of 2 hours in pigs.

Since trolamine salicylate is applied directly onto the skin, the initial thought process was to increase blood flow to the area and vasodilate the blood vessels to increase the absorption of the salicylate.

However, an earlier study provides evidence of salicylate’s ability to directly affect local tissue penetration without the need to provide systemic circulation to increase clinical effectiveness.

Data from a review of studies of osteoarthritis treatment suggests that topical analgesics may only be beneficial for the first two weeks.

A study to evaluate the efficacy of decreasing pain and stiffness of muscles when applying a 10% trolamine salicylate cream was done in patients suffering from osteoarthritis in their hands.

A one-time application of the cream was found to be safe and effective for temporary relief of minor pain and stiffness affected by osteoarthritis in the hands.

Osteoarthritis (OA) affects 240 million people globally and is the standard form of arthritis. OA primarily affects the elderly and can significantly limit independence, with pain being the most predominant symptom.

OA affects joints in your body, such as your shoulder, knee, ankle, elbow, wrist, hands, and back.

Changes seen in OA joints gradually degrade and destroy cartilage, the formation of bone spurs, inflammation, degeneration of ligaments, and menisci of the knee that may lead to chronic pain, joint instability, and stiffness.

While this condition occurs more frequently in the elderly, participation in sports-related activities while experiencing traumatic injuries can lead to OA.

Is It Safe?

Topical creams are generally safe. However, the lack of research, especially long term use, means that fully identifying the safety profile for this ingredient is not possible.

The efficacy and safety of acute topical non-steroidal anti-inflammatory drugs, including salicylate, are well studied. 43 studies confirmed that topical NSAIDs were effective and safe for osteoarthritis.

Trolamine Salicylate has no listed interactions with other drugs.

Side effects: Blistering, peeling, redness, irritation at the application site, nausea/vomiting, and ringing in the ears.

Contraindications: hypersensitivity from application to skin or site of pain.

Suggested use is for the treatment of minor muscle and/or joint pain, typically applied for adults.

If you are experiencing levels of increased pain that is not normal and new, you should notify a medical professional.

Available Alternatives

Topical pain relief creams are widely available from vendors that sell health and wellness products.

Product comparison will lead to finding a varying degree of pricing and formulation of ingredients.

Australian Dream Cream and Penetrex for Pain Relief are products that we have previously reviewed.

Both supplements contain similar ingredients that help to provide relief for joint, muscle, and back pain.

Australian Dream offers a 2 oz jar for ranging from $15-$18 (one 4 oz jar of Hempvana costs $19.99 including free shipping) and a pretty favorable safety profile.

One large 4 oz jar of Penetrex will cost you $34.95.

The Cost

Hempvana pain relief cream is available through many retailers, but purchasing a second 4 oz jar through their website can provide savings.

According to Hempvana’s website:

  • One 4 oz jar: $19.99 with free shipping
  • Two 4 oz jars: $29.98 with free shipping

A 30-Day Guarantee backs Hempvana Pain Relief Cream. To claim a full refund or replacement, you must send the item back. You will be expected to have to pay for your shipping and handling, however.

The Bottom Line

Topical creams are generally safe but more long-term studies are required. Survey results indicate that more guidance is needed to effectively prescribe topical agents to manage pain in the long term, however.

While topical analgesics may provide good levels of pain relief, it may only be limited to acute conditions of sprains, strains, and overuse injuries.

Further, topical treatments may lead to better compliance of pain when compared to oral ingestion of NSAIDs.

Hempvana Pain Relief cream is a more affordable and reasonably priced option when compared to other topical analgesic creams used for the treatment of localized pain.

Always identify the source of your symptoms before use, and the inclusion of your physician can help determine the underlying cause and provide you the best possible care.

Customer Reviews

2.7 Stars out of 29 Reviews
5 Star:31% 4 Star:10% 3 Star:3% 2 Star:3% 1 Star:51%
41% Recommend This Product
Start your review of Hempvana Pain Relief Cream:
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Posted on Dec 4, 2022

More pain after using

By Jay J. , Parker, CO

I wasn't supposed to be able to walk when I was born, my bones are greatly deformed and they all creak and run together and give me great pain. I started using it on my right knee. I blew it out when I was 15 and cannot put weight on it if it's bent. I started using this product and went from my manageable, just don't put weight on it while it's bent tatic, but the day of using it, started to get more pain than normal to within two days having the full-blown inability to move my leg on its own, have to manually move it. Wondering if anyone else has experienced this?

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

No “pros” were specified in this review

Gave me extreme pain

Worsened my condition

Did not help

Helpful Review? 1 Person Has Voted

Posted on Sep 9, 2022

Beware, doesn’t do anything!

By Suzanne S., Mississippi, Verified Reviewer

I was looking forward to receiving Hempvana as a rub for my back and hip, but sadly it did nothing at all! Was like rubbing just any lotion on. Tried it 4 times a day for the past 4 days and still nothing; so I’m sorry to say as I said in my header - BEWARE. Personally I’d recommend any of those OTC rubs for muscle pain - at least you feel something. This was very disappointing and for the price - like throwing money away. Return policy sucks - unless you have the box it came in, you can’t return it. Didn’t work for me - maybe it will for others, but final word is - beware.

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

No “pros” were specified in this review

Doesn’t do anything

Expensive since it doesn’t do anything

Lousy return policy

Helpful Review? 2 People Have Voted

Posted on Sep 6, 2022

Does not work at all!

By Thomas S., Daytona Beach, FL, Verified Reviewer

I purchased two bottles of this product off of TV and purchased their upgraded Hempvana. They were not cheap.

This product does nothing. I’ve had some very good products from different places and I was hoping this would be something good but turned out to be nothing.

And I got rid of it.

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

No “pros” were specified in this review

They said how good it was and it did nothing.

Did not like the creamy consistency, was not worth the money.

Just shows you that you could buy an item for almost $40 a bottle of their upgraded hemp Florida and get nothing for your money.

Helpful Review? 2 People Have Voted

Posted on Aug 19, 2020

Good product!

By Sandra F., Asheville, NC, Verified Reviewer

I have had scoliosis 6" rod back surgery since 16 years old and now at 57 years old have been told on disability that I needed for the past 8 years I will have to get 2 major surgeries to redo my surgery. I’ve been avoiding this so I tried Hempvana cream and WOW!

I won’t use any other creams to dull my pain on the skin with sciatica and osteoarthritis added with osteoporosis and other complications, so I know it works!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons


No odors

No pain

Feels cooler


No roll on

No rollers

Helpful Review? 1 Person Has Voted

Posted on Aug 11, 2020

The best relief cream!

By William C., Hubbard, OH, Verified Reviewer

Hello, I just had to write this review to say I have had many surgeries on my hands and on my back. I'm in pain everyday and have tried everything, but for me, this product is the best I have found. And I'm on my third jar and am going to order more. I really love this product. And I'm not getting paid to say this. It really works for me at a good price that helps me since I'm on a fixed income. Thank you, Hempvana, keep on!

Length of Use: Less than 3 months

Bottom Line: Yes, I would recommend this to a friend

Pros and Cons

It really work for me

It's a great price

Not greasy and smells nice, not menthol

No “cons” were specified in this review

Helpful Review? 5 People Have Voted

Posted on Aug 10, 2020

This stuff is junk. Does not work. Smells good and that's it. Does not relieve pain.

By Marty S., Chambersburg, PA, Verified Reviewer

Horrible. Does not work. Horrible, horrible, horrible. A total waste of $20. Bio freeze worked better than this product. I do not recommend buying this product.

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons


Does not work

Helpful Review? 2 People Have Voted

Posted on Jul 26, 2020

Not happy - does not work

By Charlie T., Hesperia, MI, Verified Reviewer

I purchased your Hempvana Cream to relieve the pain in my knee and shoulder. I have been using it like it says and I am not happy. It does not work. With the price being just about $20 you would think it would help a little bit but, I knew I should have not wasted my money. Do you offer a money-back guarantee?

Please let me know what to do with this product that you BRAG up on TV but did not do the job.

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

No “pros” were specified in this review

Your company does not answer a customer's email

Does not work

Helpful Review? 2 People Have Voted

Posted on Jul 20, 2020


By Beatriz M., El Paso, TX, Verified Reviewer

I ordered this product online on June 12th and also upgraded it to Hempvana Gold. Since then, I never received my order nor a shipping notification from them. After trying to contact them by email, I got no response from them and so I ordered it from Walgreens, which shipped it two days later!

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

I tried the product for my arthritis and it helped ease the pain

I'm disappointed that my original order was never received from the website and I obtained it from Walgreens instead

Helpful Review? 3 People Have Voted

Posted on Jun 23, 2020

I bought two jars of this for my sciatic nerve

By Daniel I., Florida, Verified Reviewer

This did not work on my sciatic nerve nor on my shoulder muscle. I guess that works for some people depending on how severe the pain is. Because everybody's pain is different than the other. I know we have to get the best relief so you need more marijuana and you just haven't got it inside.

Length of Use: Less than 3 months

Bottom Line: No, I would not recommend this to a friend

Pros and Cons

No “pros” were specified in this review

Does not work as claimed

Helpful Review? 1 Person Has Voted

Posted on May 14, 2020


By Ruby R., Texas, Verified Reviewer

I have degenerative joint disease, I have tried so many different things, including major pain killers from pain management doctors. Nothing, and I mean absolutely nothing, has ever worked for me...until now. This is a true miracle for me. It relieved my pain instantly. Being that I have tried everything under the sun I never would have bought it on my own but I tried my mom's and I couldn't believe how quickly and well it worked. I was definitely not expecting that! I am so happy to be pain-free again! I have to apply it 2 or 3 times a day but that's ok, this has given results that even oxycodone and oxycontin couldn't. I will be stocking up!

Bottom Line: Yes, I would recommend this to a friend

Helpful Review? 4 People Have Voted

Posted on May 14, 2020

No response

By Ed D., Illinois, Verified Reviewer

Ordered 3 weeks ago and they haven't shipped. Can't get any response from telephone calls or numerous e-mails. I'm beginning to think it's a scam. Can't get them to refund either as no response.

Bottom Line: No, I would not recommend this to a friend

Helpful Review? 4 People Have Voted
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