About Telogenesis by LCR Health
By supporting your body’s natural production of telomerase, Telogenesis by LCR Health is a dietary supplement that promises to deliver boosted strength and energy, a more youthful appearance, and reduced muscle and joint soreness.
In fact, the promotional video indicates it could even help support weight management, improve overall health, and potentially slow or reverse the physical and mental symptoms of aging. And all of this without the use of caffeine or synthetic additives.
To experience these benefits, the LCR Health website advertises you’ll need to take one capsule of Telogenesis per day with an 8 oz glass of water, ideally in the morning. Make sure you continue taking a dose about the same time each day for at least 30 days in order to sufficiently increase your telomerase threshold.
As a company, LCR Health manufactures a complete line of supplements (Midogen, Active-PK, and Cerastim, to name just a few) and held an A rating with the Better Business Bureau as of 7/9/18. But, does this necessarily mean that Telogenesis will ‘hack' your body into rewinding the clock and help you live a healthier, longer life, as advertised in the promo video?
This is the central question we’ll help you answer in this article. First, though, Let’s cover some quick basics we can use as a solid foundation.
The details: As outlined briefly in the Telogenesis promo video, telomeres act like the plastic caps at the end of shoelaces to help protect the DNA contained inside a chromosome. Writing for Scientific American, Jalees Rehman, adds some important details by explaining it this way:
“Telomeres are repetitive DNA sequences at the ends of chromosomes which act as protective caps. Every time a cell divides, its chromosomes undergo a doubling process so that the two daughter cells receive equal amounts of DNA. During the DNA replication and the separation of the newly formed chromosomes, small chunks of DNA are trimmed off at the end of the chromosomes. By having protective telomere caps, the shortening process only affects the telomeres and not the essential gene-encoding parts of the chromosome.”
As these telomeres increasingly shorten with every cell division, Jalees goes on to explain there’s evidence this can have a negative impact on the aging process and lead to commonly associated diseases.
But, the body has a damage-control protocol in place in the form of telomerase, an enzyme found in high levels inside stem cells that helps minimize telomere shortening during cell division. Therefore, it might make sense that—as Dr. Rand McClain proposes in the Telogenesis video—increasing telomerase levels in our body could positively affect aging.
The problem is that even though telomerase has been studied extensively since the 1980s, and earned Elizabeth Blackburn, Carol Greider, and Jack Szostak, the 2009 Nobel Prize in Physiology or Medicine, it’s still not completely understood. In fact, Jalees writes:
“Dr. Blackburn was quick to point out that these correlations do not necessarily mean that there is a direct cause and effect relationship. In fact, increasing telomerase levels ought to lengthen telomeres but in the case of cancer, too much telomerase can be just as bad as too little telomeres.”
TL;DR: In tightly controlled clinical settings, increasing telomerase enzyme levels in mice has been shown to increase telomere length, although it’s unclear if doing so will have lasting health benefits or consequences.
Now, the next logical question is: Have Telogenesis’ ingredients been clinically shown to boost telomerase levels and provide real-world aging benefits in humans?
Taking a Closer Look at Telogenesis’ Ingredients
According to the supplement facts label listed on the LCR Health website, Telogenesis contains:
- AC-11 extract 350 mg
- Astragalus membranaceus extract 150 mg
- KSM-66 Ashwagandha extract 125 mg
Manufactured by Healthycell, AC-11 is a dietary supplement in its own right made from the Uncaria tomentosa plant (more commonly known as cat’s claw), which they claim is “proven to enhance cell health by supporting your body’s natural ability to repair DNA, limit inflammation, clear out damaged cells, and enhance immune function.” However, the company doesn’t provide clinical support for these claims.
Sites like WebMD, the Natural Medicines Database, and Examine.com indicate there’s enough clinical evidence to list cat’s claw as ‘possibly effective’ for reducing osteoarthritis and rheumatoid arthritis pain, but nothing related to LCR Health’s claims for Telogenesis.
These same sites report much of the same lack of clinical evidence for astragalus and ashwagandha.
Could Telogenesis’ Ingredients Cause Side Effects?
WebMD and the Natural Medicines Database report that although cat’s claw is possibly safe for most people, it can cause headache, dizziness, and vomiting (no dosages or other specifics listed). It can also have a moderate interaction with high blood pressure and immunosuppressive medications.
They note the side effects of astragalus are not known, as well as the long-term safety of ashwagandha.
To help minimize potential side effects and interactions with any supplement, Telogenesis or otherwise, make sure you have an in-depth conversation with your doctor before placing an order.
How Much Does Telogenesis by LCR Health Cost?
You’ll pay different amounts for Telogenesis, depending on the LCR Health website you purchase from. On TheLongevityProtocol.com, you’ll pay:
- 1 Bottle: $49.95
- 3 Bottles: $134.85 ($44.95 each)
- 6 Bottles: $254.70 ($42.45 each)
On the other hand, purchasing from the main LCRHealtth.com will increase your prices to:
- 1 Bottle: $69
- 3 Bottles: $134.85 ($44.95 each)
- 6 Bottles: $254.70 ($42.45 each)
LCR Health offers a 90-day money back guarantee on all Telogenesis purchases, less return S&H, which you can request by calling 800-384-8308 or sending an email to support@LCRhealth.com.
Telogenesis vs. Other Telomere Dietary Supplements
Although the study of telomeres is a relatively new field, there are perhaps dozens of dietary supplements on the market competing with Telogenesis, many of which promote the same general claims. Here were some of the more popular options on Amazon and Google Shopping at the time of our research:
|Telogenesis by LCR Health||$49.95||AC-11 extract 350 mg, Astragalus membranaceus extract 150 mg, KSM-66 Ashwagandha extract 125 mg|
|TeloMax||$69.95||Chromium 240 mcg, Withania somnifera, Angelica sinensis, Crataegus oxyacantha, Silybum marianum, Terminalia chebula, Genistein, Cistanche, Polygonum cuspidatum|
|TA-65||$100+||Bioenhanced astragalus extract 8 mg|
|IsaGenesis from IsaGenix||$105.33 retail||Vitamins A, C, E, B12; a 1,280 mg proprietary blend of 30 ingredients|
|Enzymedica Telomere Plus||$30||Vitamin D3; a proprietary mixture of astragalus, SGS Broccoli Seed Extract, Rhodiola extract|
|Source Naturals Telomeron||$26||Vitamins D3 and B12, Astragalus, N-Acetyl Cysteine, L-Carnosine, Turmeric Rhizome Extract, Green Tea Leaf Extract, Purslane Aerial Parts Extract, Natural trans-Resveratrol, Grape Seed Extract, Tocotrienol Complex (Tocomax™)|
Given these vastly different price points and formulations, how can you make the most empowered decision?
As emphasized above, it's vital that you start by speaking with your doctor. They'll listen to your concerns, order the appropriate tests (if necessary), and provide a science-backed approach to helping you meet your health goals.
If they recommend that you pursue dietary supplements like Telogenesis, after writing about thousands of related products over the years, we've learned that you'll want only to do business with companies who:
- Support their claims with clinical evidence
- Price their products competitively
- Stand behind their products with at least a 30-day refund policy, and no restocking fees
- Come with mostly positive online customer feedback
Let’s apply these criteria to Telogenesis as we wrap everything up.
Can You Expect Longer Telomeres with Telogenesis by LCR Health?
We learned earlier there’s high-quality clinical indicating that boosting telomerase in mice can potentially increase telomere length, leading to improved overall health. In fact, much of this evidence earned Elizabeth Blackburn, Carol Greider, and Jack Szostak the 2009 Nobel Prize in Physiology or Medicine.
However, even Dr. McClain admits in the Telogenesis promotional video that the procedures used in these labs to boost telomerase levels were complicated, expensive, and not generally attainable by most of the population. But according to sites like WebMD and Examine.com, there isn’t enough clinical evidence that the ingredients found in this formulation will increase telomerase or deliver on any of the company’s advertising claims.
It’s important to balance these details by pointing out that LCR Health seems to come with a mostly positive online customer reputation, prices their supplement relatively competitively, and offers a 3-month return policy on all purchases if it doesn’t meet your needs and preferences.
We just might recommend purchasing through their TheLongevityProtocol.com website, which would save you $20 each at the time of our research.